1/8. encephalitis and chorioretinitis associated with neurotropic African horsesickness virus infection in laboratory workers. Part II. Ophthalmological findings.Four laboratory workers developed uveitis-chorioretinitis, associated with encephalitis in 3 cases. The retinitis was characterised by haemorrhages and areas of retinal oedema, most marked over the posterior polar regions, and was associated with exudative retinal detachments. The lesions progressed over weeks and showed a severe retinal arterial vasculopathy with arteriolar narrowing, ghost vessel formation and the development of optic atrophy. The picture in 2 of the patients resembled that of the acute retinal necrosis syndrome (ARN). antibodies to African horsesickness (AHS) virus were detected. The serology for AHS virus was positive in all 4 patients as well as in 5 of 15 laboratory workers from the same facility who were clinically and ophthalmologically normal. This is to our knowledge the first description of subclinical and probable clinical neurotropic AHS virus infection in man. AHS is a hitherto-unrecognised possible cause of viral retinitis and the ARN syndrome.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
2/8. Ocular features of west nile virus infection in north america: a study of 14 eyes.PURPOSE: To present a case series of ocular findings of west nile virus infection (WNVI) in north america. DESIGN: Retrospective, noncomparative, observational case series. PARTICIPANTS: All patients were referred to the authors for WNVI with ocular involvement between the years 2002 and 2005. methods: Chart review was performed on all participants. All participants underwent complete ophthalmic evaluation during each examination, including best-corrected Snellen visual acuity measurement, tonometry, slit-lamp biomicroscopy of the anterior and posterior segments, and dilated fundus examination with indirect ophthalmoscopy. Fundus photography and fluorescein angiography were also performed on all eyes. Relevant ocular findings associated with WNVI were recorded and tabulated. MAIN OUTCOME MEASURES: The authors studied the characteristics, frequency, and locations of ocular lesions found in participants' eyes. RESULTS: There were 14 eyes (7 patients) with ocular west nile virus lesions from 2002 to 2005. Average patient age was 58.4 years (range, 32-85 years). Ocular findings in descending order of frequency included multifocal chorioretinal target lesions in 12 eyes (85.7%), retinal hemorrhages in 7 eyes (50.0%), vitritis in 6 eyes (42.9%), chorioretinal linear streaks in 4 eyes (28.6%), perivascular sheathing and vasculitis in 4 eyes (28.6%), narrowed retinal vessels in 4 eyes (28.6%), disc edema in 4 eyes (28.6%), optic atrophy in 2 eyes (14.3%), vascular occlusion in 2 eyes (14.3%), and VIth nerve palsy in 1 eye (7.1%). Peripheral fundus lesions were found in all 14 eyes (100%), whereas posterior fundus lesions were found in 8 eyes (57.1%). Five patients (71.4%) were diabetic. diabetic retinopathy was present in 7 eyes (70%). CONCLUSIONS: Multifocal choroiditis is the most common ocular manifestation associated with WNVI, with a typically benign clinical course. Less frequent ocular lesions, including optic neuritis and occlusive vasculitis, frequently induce persistent and likely permanent visual deficit. Diabetic patients and those older than 50 years of age are more vulnerable to the more severe features of WNVI, including more serious ocular lesions.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
3/8. basal ganglia mass lesions in juvenile rheumatoid arthritis.A 2-year-old boy suffered aphasia, hypotonia, dystonia, and loss of activity and spontaneous speech during an active stage of juvenile rheumatoid arthritis with pericarditis, fever, anemia, and a high antinuclear antibody titer. These neurologic signs slowly improved with corticosteroid treatment but fluctuated over 1 year. The neuroimaging studies revealed irregular mass lesions in the basal ganglia bilaterally mainly involving the globus pallidus. They gradually decreased in size and almost disappeared after 1 year. A stereotactic brain biopsy revealed a slight proliferation of astrocytes. chorioretinitis was also observed during the clinical course. A chronic inflammatory process involving cerebral vessels was suspected, although angiography did not demonstrate cerebral vasculitis. The possibility of central nervous system lymphoma could not be eliminated. The type of aphasia and the relation to the lesion sites are discussed.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
4/8. Shiny multifocal chorioretinitis with papillitis.We report a case of unilateral inflammation involving the retinal pigment epithelium-choriocapillaris complex and the optic disc, characterized by multiple, small, shiny, yellowish-white subretinal lesions involving the midperiphery of the retina and associated with optic disc edema. These lesions showed hypofluorescence in the early transit phase of the fluorescein angiogram and leakage in the late phase. Perivascular staining of the retinal vessels and diffuse optic disc leakage were also present. A benign course associated with marked visual improvement and resolution of the inflammatory lesions occurred.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
5/8. Unusual central chorioretinitis as the first manifestation of early secondary syphilis.Three young, otherwise healthy patients had a similar picture of unilateral central chorioretinitis associated with severe visual loss. fluorescein angiography disclosed diffuse leakage under the neurosensory retina in the posterior pole, associated with multifocal areas of staining along the retinal vessels. Systemic examination showed a positive fluorescent treponemal antibody absorption test and a sharp increase in VDRL titers, indicative of active secondary syphilis. The patients responded dramatically to penicillin treatment, with visual recovery and resolution of the fundus lesions.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
6/8. Septic retinitis.A case of septic occlusion of the retinal vessels causing severe endophthalmitis is presented. The documentation of the retinal involvement before development of the abscess with photography and fluorescein angiography is rather exceptional. Although pars plana vitrectomy saved the eye, the vision was lost because vascular occlusion caused a retinal tear with retinal detachment.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
7/8. Birdshot retinochoroidopathy and subretinal new vessels.Decrease of visual acuity in birdshot retinochoroidopathy is due either to optic atrophy or to 3 types of macular involvement: cystoid macular oedema, geographic atrophy, or macular serous detachment. We describe 3 cases of juxtapapillary subretinal neovascularisation occurring in long-standing birdshot retinochoroidopathy. The mechanism of the formation of the new vessels is discussed.- - - - - - - - - - ranking = 5keywords = vessel (Clic here for more details about this article) |
8/8. chorioretinitis sclopetaria caused by fishing line sinker.A case of chorioretinitis sclopetaria caused by a grazing injury from a fishing line sinker was reported. A man was struck in his left orbit by the sinker, and immediately lost visual acuity. The sinker was removed, but funduscopy showed the typical appearance of chorioretinitis sclopetaria six months later. On fluorescein angiography, mottled background fluorescence appeared in a star-shaped scar. fluorescein angiography, computed tomography, and roentgenography indicated that direct damage to the ciliary vessels was present.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |