Cases reported "Brucellosis"

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1/11. brucellosis in a mother and her young infant: probable transmission by breast milk.

    brucellosis, although primarily a zoonotic infection, is also a threat for human health. infection can be transmitted to humans through direct contact with infected animals, products of conception, or animal discharges, and through consumption of potentially infected milk, milk products, or meat. Human-to-human transmission is rare. There have been case reports of transmission via blood transfusion and bone marrow transplantation from infected donors. Sexual intercourse is a possible means of transmission. Neonatal infection can be acquired transplacentally or during delivery. This report describes a mother with brucellosis who probably transmitted the infection to her 3-month-old baby by breast milk.
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2/11. Prevention of laboratory-acquired brucellosis.

    brucellosis is one of the most common laboratory-acquired infections, mostly because aerosolization is a mechanism of transmission in this setting. We report an exposure to brucella melitensis that occurred in a large microbiology laboratory and describe the strategy chosen for antibiotic prophylaxis and serological follow-up of exposed workers.
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3/11. Congenital brucellosis in a preterm neonate.

    brucellosis is primarily a zoonotic infection. Transmission to humans occurs through direct contact with infected animals or consumption of infected animal products. Human to human transmission is rare, but has been reported in association with blood transfusion, bone marrow transplantation, transplacental or perinatal exposure, during sexual intercourse and postnatally through breast milk. This report presents a case of transplacentally transmitted neonatal brucellosis.
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4/11. Isolated Brucella peritonitis in a CAPD patient.

    peritonitis is the most common complication in patients undergoing continuous ambulatory peritoneal dialysis (CAPD). brucellosis is a rare cause of bacterial peritonitis. Only 1 case was reported of a patient with brucella peritonitis during CAPD therapy. In that case, CAPD peritonitis was accompanied by acute brucellosis. We present the case of a patient with isolated brucella peritonitis receiving CAPD therapy without systemic manifestations of brucellosis who works as a farmer. Results of a serum agglutination test and blood cultures were negative; however, the patient's peritoneal fluid agglutination titer was 1:160 and samples inoculated into BACTEC (Becton Dickinson, NJ) bottles yielded brucella melitensis. Because we were unable to isolate the organism in blood samples, transmission seems to be the result of direct inoculation, rather than hematogenous spreading. Therefore, our patient represents the first case of isolated brucella peritonitis during CAPD therapy. Successful treatment was obtained by using a treatment regimen of rifampin and doxycycline.
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5/11. Person-to-person transmission of brucella melitensis.

    Human brucellosis is primarily an occupational hazard in the USA; in the middle east and africa ingestion of contaminated dairy products is an important route of infection. Whether human beings can become infected via person-to-person spread is uncertain. During an investigation of a commonsource, laboratory-associated outbreak due to brucella melitensis, biotype 3, the wife of a microbiologist with serologically proven brucellosis became infected. Her blood isolate was indistinguishable from the epidemic strain. In the absence of other risk factors, we suggest that sexual intercourse is a possible means of transmission.
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6/11. Probable breast-milk borne brucellosis in a young infant.

    A young infant with acute brucellosis is reported. He presented with a septicaemia-like picture. diagnosis was based on a fourfold rise of Brucella agglutination titres and a positive blood culture. He had been exclusively breast-fed when his mother developed brucellosis 4 weeks after delivery. It is strongly suspected that the transmission of brucella melitensis to this infant was through the maternal breast-milk.
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7/11. Recurrent enterocolitis-like symptoms as the possible presenting manifestations of neonatal brucella melitensis infection.

    A premature infant had three episodes of enterocolitis-like symptoms during the first three months of life. brucella melitensis was isolated in a prolonged blood culture on day 85. The clinical manifestations disappeared under treatment and did not recur. A maternofetal transmission is suggested in this case. The importance of prolonged blood cultures when brucellosis is epidemiologically suspected is emphasized.
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8/11. brucellosis of the central nervous system. A case report of an infected infant.

    brucellosis in early infancy is unusual and reports of congenitally acquired infection are extremely rare. The patient presented at the age of 8 months with high fever and signs of meningitis. He had a previous history of hydrocephalus undergoing shunt alleviation at 1 month of age. A diagnosis of central nervous system (CNS) brucellosis was subsequently made. Transplacental transmission is offered as a possible explanation for the acquisition of this child's brucellosis infection.
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9/11. Probable transmission of brucellosis from breast milk to a newborn.

    The first case of neonatal brucellosis is described. The baby was fed breast milk only when the mother became acutely ill with fever, arthralgia and malaise. At the same time the baby was febrile. Blood cultures grew brucella melitensis in both mother and child. The brucella agglutination titre in the breast milk was 1:2560. Both mother and child recovered during treatment with streptomycin.
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10/11. Neonatal brucellosis.

    Three Arab children with neonatal brucellosis are described. The first presented with late neonatal hyperbilirubinaemia, the second with a septicoemia-like picture and the third was born prematurely and presented with respiratory distress. The diagnosis of brucellosis was based on a positive blood culture and on a high or rising titre of antibodies to the Brucella organism. All the three neonates responded well to antibiotic therapy as monitored by a Brucella titre of less than 1:40 and a negative blood culture 10 weeks after the onset of therapy. The three mothers had Brucella infections during pregnancy and the Brucella agglutination titre of the breast milk was high. No Brucella microorganism was isolated from the breast milk. The mode of transmission of brucellosis in neonates is discussed.
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