1/6. brucella suis infection in philadelphia. A survey of hog fever and asymptomatic brucellosis.Examination of hospital and public health records revealed 19 cases of brucellosis diagnosed in philadelphia between 1968 and 1972. A serologic survey at philadelphia's largest hog-processing plant, however, indicated infection in 39% of workers. If extrapolated industry-wide, the total would be several hundred in philadelphia. The infection is usually unrecognized or asymptomatic, since men were active in physically demanding jobs with agglutinin titers in excess of 1:5000. Overt illness, usually first diagnosed after weeks of incapacity, responded readily to tetracycline therapy. Although clinical manifestations are nonspecific, attention to occupational history should quickly lead to the diagnosis. It is emphasized that any hog-processing plant, wherever located, is potentially a reservoir of brucellosis. Prolonged morbidity and loss of production time might be avoided if physicians were more alert to this infection. agglutinins in possibly significant titers were also found in a small fraction of persons without identifiable exposure.- - - - - - - - - - ranking = 1keywords = physical (Clic here for more details about this article) |
2/6. bone marrow hypoplasia during Brucella infection.pancytopenia, although mainly reported in adults, has also been described in children with brucellosis. However, bone marrow hypoplasia is a rare feature of the infection. An 11-year-old boy was admitted with fever, vomiting, and abdominal pain of 10 days' duration. On physical examination, pallor and high fever were detected in the absence of lymphadenopathy and hepatosplenomegaly. His hemoglobin was 8.6 g/dL, white blood cell count 1,100/mm(3), neutrophil count 500/mm(3), platelets 56,000/mm(3), and reticulocytes 0.1%. Hypocellular bone marrow was found by aspiration, and bone marrow biopsy revealed hypocellularity. The agglutination titer was greater than 1/640. trimethoprim/sulfamethoxazole was prescribed. His fever subsided and pancytopenia subsequently improved. pancytopenia associated with brucellosis is attributed to hypersplenism, hemophagocytosis, and granulomatous lesions of the bone marrow, which is usually hypercellular. bone marrow hypoplasia is rarely reported and should be kept in mind in the etiology of aplastic anemia in a country where brucellosis is frequently encountered.- - - - - - - - - - ranking = 13.104600694444keywords = physical examination, physical (Clic here for more details about this article) |
3/6. gaucher disease and brucella: just a mere coincidence?gaucher disease type I and brucellosis are chronic diseases with similar symptoms and physical signs though the former is the most common lysosomal storage disease and the latter is an infectious disease. The similarities between these diseases make differential diagnosis difficult. Immunodeficiency is a feature of gaucher disease type I and increases the susceptibility towards infections. A gaucher disease type I patient with brucellosis is presented with improvement after treatment of brucellosis.- - - - - - - - - - ranking = 1keywords = physical (Clic here for more details about this article) |
4/6. Spontaneous bacterial peritonitis due to Brucella infection.Brucella infection is a systemic disease, but the microorganism rarely causes infections in the gastrointestinal system such as hepatitis, cholecystitis, colitis and pancreatitis. Spontaneous bacterial peritonitis due to Brucella is extremely rare. Herein, we report a case of cirrhosis complicated with nongranulomatous hepatitis and peritonitis, both due to Brucella. A 63 year-old man with diabetes mellitus was admitted to hospital with complaints of weakness, backache, abdominal pain and abdominal swelling. On the basis of physical examination and laboratory findings, cryptogenic cirrhosis and spontaneous bacterial peritonitis were diagnosed. Due to persistent fever and backache, serum Brucella agglutination test was performed and found to be positive. brucella melitensis was isolated from ascitic fluid culture. liver biopsy findings revealed cirrhosis and a nongranulomatous hepatitis which was thought might be due to Brucella infection. doxycycline and rifampicin, in addition to diuretics were administered for spontaneous ascites infection due to Brucella. A week later, the patient's condition improved and he became afebrile. After two months of therapy, the ascites had almost disappeared.- - - - - - - - - - ranking = 13.104600694444keywords = physical examination, physical (Clic here for more details about this article) |
5/6. guillain-barre syndrome associated with acute neurobrucellosis.We report the case of a 14-year-old girl with guillain-barre syndrome associated with brucellosis due to brucella melitensis. The diagnosis was established by the isolation of B. melitensis from her blood and by the determination of high levels of Brucella aglutinins in her sera and cerebrospinal fluid. A combination of rifampin, co-trimoxazole and physical therapy resulted in complete healing within 30 days. Antibrucellar treatment continued for 12 weeks. This case report suggests that brucellosis should be kept in mind in the aetiology of guillain-barre syndrome in the endemic areas for brucellosis, and bacteriological and serological tests for brucellosis should be performed.- - - - - - - - - - ranking = 1keywords = physical (Clic here for more details about this article) |
6/6. Lumbar spinal root compression caused by Brucella granuloma.STUDY DESIGN: A case report of rarely seen extradural brucellosis granuloma causing spinal root compression in the lumbar region. OBJECTIVE: To point out the possibility of extradural compression caused by brucellosis. SUMMARY OF BACKGROUND DATA: Many investigators have indicated that myelopathy or radiculopathy caused by irritation or compression by tiny abscess, disc herniation, or extradural granuloma may occur in brucellosis. Failure to make the correct diagnosis is possible because of the absence of such symptoms of brucellosis as fever, sweating, or fatigue and because findings of physical examination, radiography, and myelography indicate intervertebral disc herniation. methods: review and discussion of the case history are presented. RESULTS: Brucella granuloma compressing the right L5 root and dural sac was diagnosed on computed tomographic scans and was excised subtotally after laminectomy and facetectomy. CONCLUSION: The possibility of extradural compression caused by brucellosis should be considered in endemic areas and must be differentiated from an intervertebral disc herniation by means of agglutination testing and bone scan.- - - - - - - - - - ranking = 13.104600694444keywords = physical examination, physical (Clic here for more details about this article) |