1/27. diabetes insipidus in neurobrucellosis.brucellosis is an infection due to Brucella species and is characterized by acute febrile illness, chilly sensations, sweats, weakness, generalized malaise, body aches and headache. The involvement of the nervous system is rare. A few cases have been reported with symptoms and sign of optic neuritis, meningoencephalitis, meningomyelitis and cranial nerve palsy. We report a case with culture proven neurobrucellosis who presented with diabetes insipidus along with systemic signs. neuroimaging revealed multiple lesions in brain parenchyma, including the suprasellar region. Both diabetes and suprasellar lesions improved markedly with specific antibiotic therapy.- - - - - - - - - - ranking = 1keywords = nervous system, brain (Clic here for more details about this article) |
2/27. Thrombocytopenic purpura associated with brucellosis: report of 2 cases and literature review.Mild hematologic abnormalities are common in the course of human brucellosis; however, they generally resolve promptly with treatment of the disease. Occasionally, thrombocytopenia is severe and can be associated with bleeding into the skin (purpura) and from mucosal sites. We describe 2 patients infected with brucella melitensis who presented with thrombocytopenic purpura, and we review 41 additional cases from the literature. patients ranged in age from 2 to 77 years, and both sexes were affected equally. In the majority of cases, examination of the bone marrow revealed abundant megakaryocytes. Possible mechanisms involved in thrombocytopenia include hypersplenism, reactive hemophagocytosis, and immune destruction of platelets. Recognition of this complication is essential, since hemorrhage into the central nervous system is associated with a high mortality rate.- - - - - - - - - - ranking = 2.5892736149587keywords = central nervous system, nervous system (Clic here for more details about this article) |
3/27. Neurobrucellosis.brucellosis, which is endemic in saudi arabia, can present as a disease with multisystem involvement. Occasionally the organisms invade the central nervous system producing varied neurological manifestations. Often the clinical diagnosis of neurobrucellosis is not straight forward and is obscure. Certain criteria have to be fulfilled for the definitive diagnosis of neurobrucellosis. We report 2 cases of neurobrucellosis which were encountered for the first time during the past 10 years at this hospital.- - - - - - - - - - ranking = 2.5892736149587keywords = central nervous system, nervous system (Clic here for more details about this article) |
4/27. Brucellar spondylitis and meningoencephalitis: a case report.brucellosis, a zoonosis with a worldwide distribution, is a systemic infection that can present with involvement of both nervous and musculoskeletal systems. We report a case of spondylitis and meningoencephalitis and describe the clinical features, and difficulties in treatment. Osteoarticular complications of brucellosis are common but involvement of the nervous system is rare and it should be included in the differential diagnosis of any obscure neurologic disorder.- - - - - - - - - - ranking = 0.91486679545keywords = nervous system (Clic here for more details about this article) |
5/27. Focal cerebral involvement by neurobrucellosis: pathological and MRI findings.Central nervous system involvement by brucellosis is infrequent and usually presents as acute meningoencephalitis. Neurobrucellosis presenting as a focal brain mass has rarely been demonstrated on imaging studies. We describe the imaging and pathologic findings in a child affected by neurobrucellosis with focal cortico-subcortical involvement.- - - - - - - - - - ranking = 1keywords = nervous system, brain (Clic here for more details about this article) |
6/27. Epileptic seizure: an atypical presentation in an adolescent boy with neurobrucellosis.brucellosis is an infectious disease with multisystemic involvement caused by the genus Brucella. Neurological complications, including meningitis, meningoencephalitis, myelitis-radiculoneuritis, brain abscess, epidural abscess and meningovascular syndromes, are rarely encountered. We present a patient with epileptic seizures and aggressive mood due to chronic neurobrucellosis of 2.5 y duration, which was misdiagnosed as bacterial meningitis and epilepsy. This form of presentation has not previously been reported in the English language literature. We conclude that the diagnosis of neurobrucellosis should be considered in patients presenting with recurrent or chronic meningitis syndromes with or without seizure from endemic areas for brucellosis.- - - - - - - - - - ranking = 0.085133204549996keywords = brain (Clic here for more details about this article) |
7/27. A child with neurobrucellosis.An 11-year-old boy presented with chronic meningitis followed by acute flaccid paralysis. The aetiology remained uncertain until the brucellar serology test became positive and there was a good response to specific antimicrobial therapy. Nerve conduction studies confirmed a proximal radiculopathy. awareness of the condition and performance of the appropriate tests will differentiate neurobrucellosis from other chronic central nervous system infections.- - - - - - - - - - ranking = 2.5892736149587keywords = central nervous system, nervous system (Clic here for more details about this article) |
8/27. Neurobrucellosis.A six years old female had high-grade fever and two episodes of focal convulsions. Systemic examination was normal. Widal test was repeatedly positive. MRI-brain showed bilateral cerebritis. blood antibody titers against brucella were positive. She responded to 6 months therapy with doxycycline, rifampicin and gentamicin replaced with streptomycin after 21 days.- - - - - - - - - - ranking = 0.085133204549996keywords = brain (Clic here for more details about this article) |
9/27. Abducent nerve palsy during treatment of brucellosis.brucellosis is an infectious disease with multisystem involvement caused by the genus Brucella. Neurological complications including meningitis, meningoencephalitis, myelitis-radiculoneuritis, brain abscess, epidural abscess, and meningovascular syndromes are rarely encountered. We present here a patient with sixth cranial nerve palsy that occurred during treatment for brucellosis, a form of presentation rarely been reported in English-language literature. We conclude that neurobrucellosis, pseudotumor cerebri, and side effects of tetracyclines which are frequently used in brucellosis should be kept in mind when considering intractable headaches and cranial nerve palsies in patients with brucellosis.- - - - - - - - - - ranking = 0.085133204549996keywords = brain (Clic here for more details about this article) |
10/27. Immune thrombocytopenic purpura associated with Brucella and toxoplasma infections.Bacterial and protozoal infections can cause thrombocytopenia and may mimic idiopathic thrombocytopenic purpura (ITP). Brucella species and toxoplasma are among the infectious agents with protean clinical manifestations which may induce immune thrombocytopenia. In rare cases, thrombocytopenia can be severe and may result bleeding into the skin and from mucosal sites. Prompt recognition of this complication and aggressive therapy are essential, since the mortality associated with bleeding into the central nervous system is high. We report two patients with complaints of severe epistaxis and thrombocytopenia associated with brucellosis and toxoplasmosis. Thrombocytopenic purpura in these cases responded well to the high-dose corticosteroid treatment with platelet recovery within 2-3 days. For cases with infection-induced immune thrombocytopenic purpura, short-term high-dose corticosteroids may be applied as an urgent therapy without worsening of the clinical condition.- - - - - - - - - - ranking = 2.5892736149587keywords = central nervous system, nervous system (Clic here for more details about this article) |
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