Cases reported "Breast Neoplasms, Male"

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1/6. A case report of advanced male breast cancer with an objective response to tamoxifen treatment.

    A 70-year-old man presented with a firm tumor in his right breast first noticed eight years ago.The tumor had enlarged gradually and had produced an ulcer with bleeding. On physical examination, a huge tumor entirely occupied the right breast and extensively had infiltrated the chest wall.Chest X-ray and CT showed massive pleural effusion and multiple small nodular lesions in the lung. Invasive ductal carcinoma of the breast was diagnosed by incisional biopsy,confirming advanced breast cancer with lung metastases and bilateral pleural effusion(T4cN2M1, Stage IV). Because ER and PgR levels were 110 fmol/mg and 190 fmol/mg, respectively, and because his general condition was poor, we selected medical treatment with tamoxifen(TAM). Thirty-two weeks later, the tumor had showed pronounced reduction with scarring. The patient underwent local excision of the scar tissue. The quality of life of the patient was favorably improved and no severe adverse events were observed. The tumor in the chest wall recurred two months after the end of TAM treatment, possibly because the patient did not accept continuous TAM therapy. The patient died from complications of brain metastasis 32 months after the start of TAM treatment. We report a rare case of advanced male breast cancer and on the effectiveness of continuous TAM treatment.
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2/6. Intracystic breast carcinoma in a male: Unusual case presentation and literature review.

    breast carcinoma in males is rare and accounts for 0.5-1.5% of all breast carcinomas. Intracystic breast carcinoma is distinctly uncommon and represents approximately 5-7.5% of all breast cancers in males. On physical examination and radiologic imaging, these lesions often appear benign; however, the presence of an intracystic solid component is typical and should raise the suspicion of carcinoma. We report an unusual case of intracystic breast carcinoma presenting in a male and review the literature.
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3/6. male inflammatory breast cancer.

    A case of a 48-year-old male with an inflammatory breast cancer is used to illustrate this uncommon malignancy. The physical examination of thickening and erythema made the clinical diagnosis. Mammographic findings of increased density in the right breast with coarsened stroma and an underlying mass confirmed the clinical findings. The sonographic evaluation revealed a 2-cm ill-defined hypoechoic mass. The pathologic examination of the mastectomy specimen showed an infiltrating duct cell carcinoma with lobular features. male breast cancer afflicts 1500 men each year. Clinically it must be differentiated from gynecomastia, a much more common and benign condition.
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4/6. Fine-needle aspiration diagnosis of plasmacytoma presenting as breast masses in a patient on estrogen therapy for prostate cancer.

    We describe a 79-yr-old man with a history of androgen-independent metastatic prostate cancer treated with exogenous estrogens presenting with bilateral breast masses associated with bilateral axillary lymphadenopathy. Although the findings on physical examination with the concomitant history of estrogen therapy for metastatic prostate cancer raised the clinical suspicion of breast cancer, fine-needle aspiration (FNA) cytology identified the lesions as multiple myeloma.
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5/6. A large benign vascular neoplasm of the male breast. A case report and review of the literature.

    breast hemangiomas are extremely rare neoplasms in the male population. We report a case of a 77-year old man with a breast hemangioma which was detected in physical examination as a small nodule ten years after a chest injury. The final histological diagnosis was hemangioma of the breast, 6 cm in the largest diameter. To our knowledge, this is the largest benign vascular breast neoplasm in a male patient reported up to date. The mammographic and pathologic findings in this case are presented. The rarity of the lesion and its differential diagnosis from angiosarcoma are discussed while the problems encountered in the correct diagnosis and classification of this tumor are also presented. The need for extreme caution in the interpretation of the histological characteristics of all palpable vascular tumors of the breast is emphasized.
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6/6. Intraduct papillomatosis of the breast in a peripubertal male.

    A 13-year-old boy presented with right-sided gynecomastia. Histological examination of the excised specimen revealed distention of ducts by papillary configurations of proliferating epithelium. The boy had no known family history of breast disease and physical examination revealed minor dysmorphic features, but a karyotype was normal. The possible relationship of this lesion to other proliferative lesions described in the pubertal male breast is discussed.
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