Donor-Specific HLA Alloantibodies in Liver Transplantation
Even though the detrimental effects of DSA on outcomes following renal transplantation have been recognized since 1969, our understanding of their pathologic impact continues to evolve. It is clearly demonstrated that other solid organ allografts are ...
Medscape - Thu, 08 May 2014 21:15

Treatment of mCRCP
The major biologic processes under therapeutic investigation in prostate cancer involve growth and survival, chemotherapy and hormone therapy resistance, extragonadal androgen production, modulation of the androgen receptor, angiogenesis, the bone ...
UroToday - Fri, 17 Oct 2014 00:30

Fetal Cells Function in Parkinson's Brains Years Later
Rarely, transplanted cells develop Lewy body–like inclusions, presumably from toxic proteins secreted by neighboring neurons that remain in the grip of continuing pathology. The researchers cite studies that indicate downregulation of DATs in ...
Medscape - Fri, 06 Jun 2014 07:12

First fMRI images of individual neurons
A research team from CEA NeuroSpin and the Institut de neurosciences cognitives et intégratives d'Aquitaine (CNRS/Université de Bordeaux) demonstrated the possibility to obtain functional magnetic resonance images (fMRI) with single cell resolution.
Medical Xpress - Wed, 04 Jun 2014 03:52

Advanced Computational Network Modeling Offers Clues To Pulmonary ...
... volume overload, and death. However, the molecular processes by which diverse upstream stimuli result in PH remain enigmatic. Research in the ... The disease is marked by a pathologic imbalance of complex molecular pathways that in turn promote a ...
Pulmonary Hypertension News - Thu, 26 Jun 2014 12:18

Does Pay-for-Performance Improve Surgical Outcomes?
Evaluations of this first phase of the program showed limited improvement in processes of care and no significant improvements in patient outcomes, including surgery. Because the program initially only rewarded hospitals in the top-2 deciles of ...
Medscape - Tue, 20 May 2014 21:18

Blood Test Predicts Breast Cancer Relapse
The fifth patient who relapsed had an isolated relapse in the brain on trastuzumab after achieving a pathologic complete response in the primary breast tumor, and did not have detectable cfDNA mutations at relapse. "That coincides with recent data ...
Medscape - Mon, 09 Jun 2014 13:15

Data from Bayer Oncology Portfolio and Pipeline to be Presented at ASCO 2014
In in vitro studies, Nexavar has been shown to inhibit multiple kinases thought to be involved in both cell proliferation (growth) and angiogenesis (blood supply) – two important processes that enable cancer growth. These kinases include Raf kinase ...
PR Newswire (press release) - Wed, 14 May 2014 14:00

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Last update: September 2014