Pulse wave velocity correlates with aortic atherosclerosis assessed with ...
However, many different biological processes have been proposed to be involved in increased aortic stiffness. In fact, the link between aortic .... Atheromatous disease of the thoracic aorta: pathologic and clinical implications. Ann Intern Med 1997 ...
Nature.com - Thu, 23 Apr 2015 02:11



Amyloid Imaging: What Is Its Role?
Amyloid is one of the hallmark "pathologic processes" of Alzheimer disease and may be the earliest biomarker, perhaps predating clinical disease onset by as long as a decade. In fact, some clinical trials of therapeutic compounds have used amyloid ...
Medscape - Tue, 14 Apr 2015 09:07

Gephyrin: a central GABAergic synapse organizer
Synapses form via a coordinated process that orchestrates (sequentially or in parallel) a variety of dynamically regulated cellular events. Various molecular and cellular mechanisms underlying synapse formation have been elucidated. For example ...
Nature.com - Thu, 16 Apr 2015 23:56



Exelixis (EXEL) Stock Rises Today Following FDA Fast Track Designation
The fast track designation is designed to expedite the review process for treatments of fatal diseases that do not already have viable alternatives for treatment. With the designation, cabozantinib is now also eligible for a Priority Review of a New ...
TheStreet.com - Thu, 09 Apr 2015 11:33

Exelixis' Cabozantinib Granted Fast Track Designation by FDA For Advanced ...
MarketWatch - Thu, 09 Apr 2015 05:33

FDA grants fast track status to Cometriq for advanced renal cell carcinoma
Healio - Thu, 09 Apr 2015 09:41

Exelixis' cabozantinib granted Fast Track designation by FDA for advanced ...
European Pharmaceutical Review - Thu, 09 Apr 2015 07:37

US FDA grants Fast Track designation to Exelixis' cabozantinib for RCC treatment
pharmabiz.com - Sat, 11 Apr 2015 00:18



In-Depth Overview of Mechanical Ventilation
When ventilation and perfusion are adequate enough to maintain homeostasis, we refer to this as “ventilation/perfusion matching” or “V/Q match” for short. When this isn't occurring because of some pathologic process such as respiratory failure or ...
JEMS.com - Mon, 30 Mar 2015 18:07



Heart attack: Minute-by-minute look at life and death battle
Here, we follow Wilson's heart attack minute by minute, recounting the pathologic processes in his body that led to a serious blockage in his right coronary artery - as well as the minute-by minute response. April 17, 2014, 10 p.m.: Wilson kisses his ...
MassLive.com - Mon, 06 Apr 2015 12:30

Bilirubin production and hour-specific bilirubin levels
This phenomenon is the result of a pathologic imbalance between bilirubin production and elimination. Increased production and/or decreased elimination of bilirubin have been considered as the contributing causes for neonatal jaundice and the ...
Nature.com - Thu, 16 Apr 2015 07:03



Interpreting Toxicity's Portents
NPOT enables the formation and label-free identification of macromolecular complexes involved in physiological or pathological processes, and is particularly effective for identifying the on- and off-target actions of therapeutic molecules. Protein ...
Genetic Engineering & Biotechnology News - Tue, 31 Mar 2015 13:02


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