Low Sleep Quality Linked to Dementia Pathology
"Our findings suggest that hypoxia during sleep and reductions in [slow wave sleep] may contribute to the major pathologic processes underlying cognitive decline in the elderly," the researchers conclude. They add, "How [slow wave sleep] may have a ...
Medscape - Thu, 11 Dec 2014 16:22



Does Poor Sleep Lead to Dementia?
While the prospective findings cannot show a causative link between sleep issues, such as sleep apnea and emphysema, in old age and age-related cognitive decline, the findings suggest these factors may contribute to the major pathologic processes ...
MedPage Today - Thu, 11 Dec 2014 11:52

The Gut and Arthritis: The Evidence Grows
It has been hypothesized that HLA-B27 induces AS by effects on the gut microbiome, in turn driving spondyloarthritis-inducing immunological processes such as IL-23 production. "Our data here showing intestinal dysbiosis in AS cases is ... Furthermore ...
MedPage Today - Thu, 11 Dec 2014 17:05

Genetics of Amyotrophic Lateral Sclerosis
There currently is no stated role for neuroimaging to support the diagnosis of ALS; however, diagnosis requires absence of neuroimaging evidence of other disease processes that may explain the observed clinical and electrophysiological signs.4,5 ...
AJNR (subscription) - Mon, 15 Dec 2014 08:07

Air quality and its impact on transplants
Beyond these processes that directly link particulate matter to an autoimmune response, Mezrich says it's possible that pollution could have more subtle and indirect effects on transplant tolerance. If a person spends years inhaling foreign particles ...
Medical Xpress - Thu, 11 Dec 2014 06:03

Exelixis Announces Results from the COMET-2 Pivotal Phase 3 Trial of ...
These receptor tyrosine kinases are involved in both normal cellular function and in pathologic processes such as oncogenesis, metastasis, tumor angiogenesis, and maintenance of the tumor microenvironment. COMETRIQ® (cabozantinib) is currently ...
PipelineReview.com (press release) - Mon, 01 Dec 2014 04:56

What is an 'adverse event,' more from California Department of Public Health
Death during or up to 24 hours after induction of anesthesia after surgery of a normal, healthy patient who has no organic, physiologic, biochemical, or psychiatric disturbance and for whom the pathologic processes for which the operation is to be ...
News10.net - Thu, 20 Nov 2014 21:15



Epidemic spreading and neurodegenerative progression
The authors' model relies on the striking similarity between intra-brain pathology propagation processes and the spread of human infectious diseases. They demonstrate that the brain's connections between cells play a similar role in misfolded protein ...
EurekAlert (press release) - Thu, 20 Nov 2014 11:07


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Last update: September 2014