Identification of microRNA expression profile related to lymph node status in ...
They have been linked to a variety of physiologic and pathologic processes, including carcinogenesis and can act as metastatic activators or suppressors. Recently, miRNA signatures have been related to the pathologic characteristics and prognosis of EC.
Nature.com - Fri, 05 Feb 2016 04:33



Nifuroxazide exerts potent anti-tumor and anti-metastasis activity in melanoma
Stat3 plays a critical role in the regulation of fundamental biological processes, such as cell proliferation, apoptosis, angiogenesis, invasion and metastasis. Besides, Stat3 can also lead to suppression of the innate and adaptive immune response by ...
Nature.com - Tue, 02 Feb 2016 02:49

POINT-COUNTERPOINT: Sequential Therapy for mCRC
... approved regorafenib, an orally active inhibitor of angiogenic tyrosine kinases (including the VEGF receptors 1, 2, and 3), as well as several other membrane-bound and intracellular kinases involved in normal cellular function and in pathologic ...
LWW Journals - Mon, 01 Feb 2016 15:48

Exelixis Announces European Medicines Agency Acceptance of Marketing ...
These receptor tyrosine kinases are involved in both normal cellular function and in pathologic processes such as oncogenesis, metastasis, tumor angiogenesis and maintenance of the tumor microenvironment. Cabozantinib, marketed under the brand name ...
Business Wire (press release) - Thu, 28 Jan 2016 13:00

Zafgen's Pivotal Phase 3 Trial of Beloranib in Prader-Willi Syndrome Achieves ...
Pathologic hunger-related behaviors, known as hyperphagia, dominate the lives of individuals with PWS, and drive patients to engage in problematic behaviors which can lead to excessive overeating, choking, and stomach rupture. Compounding the morbid ...
CNNMoney - Wed, 20 Jan 2016 02:52

Exelixis Announces Positive Overall Survival Results from METEOR, the Phase 3 ...
These receptor tyrosine kinases are involved in both normal cellular function and in pathologic processes such as oncogenesis, metastasis, tumor angiogenesis and maintenance of the tumor microenvironment. Cabozantinib, marketed under the brand name ...
Business Wire (press release) - Mon, 01 Feb 2016 04:56



Examining Synthetic Biologics' Distruptive Approach To Obesity
Given those countries such as Japan use a BMI of 25, the numbers could be far worse as the U.S. seems to be in a process of normalizing deviancy. If current trends continue, it is estimated that by 2030, 51% of the population will be obese. Current ...
Seeking Alpha - Mon, 25 Jan 2016 05:05



Human DNA methylomes of neurodegenerative diseases show common epigenomic patterns
The classification of patients into different neurodegenerative disease categories according to the preponderance of symptoms has been important for gaining insight into their pathological hallmarks but it is striking that often no clear distinctions ...
Nature.com - Tue, 19 Jan 2016 06:41


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