Combined transcriptome studies identify AFF3 as a mediator of the oncogenic ...
A better understanding of the biological processes affected by Wnt/β-catenin pathway alterations in ACC may allow the identification of therapeutic targets and thereby contribute to the development of new therapeutic strategies. The aim of this study ...
Nature.com - Mon, 27 Jul 2015 06:18

New Clues to Schizophrenia Pathogenesis
... on the bacterial components of the microbiome, and focusing only on bacteria misses out on the possible contribution that viruses ― including viruses that infect bacteria ― fungi, and protozoa could make to different pathologic processes, said Dr ...
Medscape - Thu, 09 Jul 2015 05:18



Evaluating cell cycle gene expression for prostate cancer prognosis
Kaplan-Meier plot of time to prostate cancer recurrence (top) or death (bottom), according to the percentile distribution of the mean expression levels of 30 cell cycle-regulated genes. Hazard ratio (HR) and 95% confidence interval (95% CI) associated ...
Fred Hutch News Service - Mon, 20 Jul 2015 09:52

Exelixis Announces Positive Top-Line Results from METEOR, the Phase 3 Pivotal ...
These receptor tyrosine kinases are involved in both normal cellular function and in pathologic processes such as oncogenesis, metastasis, tumor angiogenesis, and maintenance of the tumor microenvironment. COMETRIQ® (cabozantinib) is currently ...
Business Wire (press release) - Mon, 20 Jul 2015 03:52

Exelixis Announces Start of Phase 1 Trial of Cabozantinib in Combination with ...
These receptor tyrosine kinases are involved in both normal cellular function and in pathologic processes such as oncogenesis, metastasis, tumor angiogenesis, and maintenance of the tumor microenvironment. COMETRIQ® (cabozantinib) is currently ...
MarketWatch - Mon, 13 Jul 2015 05:33

MR Imaging of Pericardial Diseases
The pericardium can be affected by infectious or inflammatory processes causing pericarditis; accumulation of excess fluid, causing tamponade, thickening and scarring of the layers leading to constriction; primary and metastatic neoplasms, and ...
Medscape - Thu, 09 Jul 2015 20:56

Biomarkers in Drug Discovery – Integration in Early Stage Promotes Use of ...
According to Food and Drug Administration (FDA), a biological marker or biomarker is defined as a characteristic that is objectively measured and evaluated as an indicator of normal biologic processes, pathogenic processes, or biological responses to a ...
Medgadget.com (blog) - Tue, 21 Jul 2015 10:37

Acute exposure to silica nanoparticles aggravate airway inflammation ...
In particular, the application of nanotechnology in the medical field has improved various biotechnological processes such as drug synthesis and their targeted delivery. Nanotechnology is expected to progress and expand in the future. The increasing ...
Nature.com - Thu, 16 Jul 2015 23:56


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