Differential miRNA expressions in peripheral blood mononuclear cells for ...
Early-stage solid tumors may have higher cell growth potential and lesser frequently undergo apoptosis and necrosis processes compared with advanced stage tumors, thus yielding limited amount of the circulating extracellular molecules. Therefore, the ...
Nature.com - Mon, 06 Jul 2015 05:33



New research probes key component of the immune system
Blattman and his colleagues are working on a new project to better understand the subtle biological dance that determines whether CD8 T cells will be ineffective, protective or pathologic in response to viral infection. The research may yield vital ...
Arizona State University - Thu, 25 Jun 2015 14:22

Evaluation of targeted therapies in advanced breast cancer: the need for large ...
... translated at the protein level. Last, (vii) accurate knowledge of the pharmacology of the targeted agents under assessment, as well as thorough target validations processes in place, before matching targeted compounds for patients bearing specific ...
Nature.com - Mon, 29 Jun 2015 02:56

mRNA expression of genes involved in inflammation and haemostasis in equine ...
Equine septic arthritis and rheumatoid arthritis (RA) in humans are both characterized as severe inflammatory conditions showing similar pathologic occurrences such as intra-articular cell recruitment and synoviocyte driven cytokine release [4], [6 ...
BMC Blogs Network - Fri, 26 Jun 2015 07:15

Genetic evidence in the mouse solidifies the calcium hypothesis of myofiber ...
Increased calpain activity can exacerbate pathology in MD by cleaving critical intracellular proteins, and not surprisingly, calpain activity is increased in muscle from mdx mice. To test the involvement of calpains in the MD disease process, Spencer ...
Nature.com - Fri, 19 Jun 2015 05:01

4th International Conference on Pediatrics
Researchers are engaged in a variety of laboratory and clinical research programs to extend their understanding of the developing nervous system and pathologic processes that underlie neurological disorders in children. The most common neurological ...
The Hudson Reporter - Tue, 02 Jun 2015 13:37



Amyloid Imaging: What Is Its Role?
Amyloid is one of the hallmark "pathologic processes" of Alzheimer disease and may be the earliest biomarker, perhaps predating clinical disease onset by as long as a decade. In fact, some clinical trials of therapeutic compounds have used amyloid ...
Medscape - Tue, 14 Apr 2015 09:15



Low Sleep Quality Linked to Dementia Pathology
"Our findings suggest that hypoxia during sleep and reductions in [slow wave sleep] may contribute to the major pathologic processes underlying cognitive decline in the elderly," the researchers conclude. They add, "How [slow wave sleep] may have a ...
Medscape - Thu, 11 Dec 2014 16:33

Does Poor Sleep Lead to Dementia?
MedPage Today - Thu, 11 Dec 2014 12:00


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Last update: September 2014