Breakthrough T-Cell Therapy Halts EBV-Associated Lymphoproliferative Disorders
Infusions of Epstein-Barr virus (EBV)–specific cytotoxic T lymphocytes (CTLs) from healthy donors led to high response rates and significant extensions in overall survival (OS) for patients with rituximab-refractory EBV–associated lymphoproliferative ...
OncLive - Sun, 19 Apr 2015 06:10



Treatment Strategies to Optimize Outcomes With Brentuximab Vedotin ...
Patients who are immunosuppressed or have concomitant hematologic malignancies are at risk of developing PML.21 PML is estimated to occur in 0.07% to 0.52% of patients with lymphoproliferative disorders who are treated with chemotherapy.21-23 PML ...
Targeted Oncology - Tue, 19 May 2015 09:30

Engineering haploidentical transplants
By depletion of CD45RA+ cells, there was also a significant depletion of B cells thereby minimizing the risk of post-transplant EBV lymphoproliferative disease. To further maximize the GVL potential of the graft, Triplett et al also infused donor NK ...
Nature.com - Mon, 11 May 2015 06:43



Likely trigger for autoimmune disease found in newly-discovered rogue cells
Mutated FAS has already been linked to autoimmune disease. Patients with FAS mutations develop autoimmune lymphoproliferative syndrome (ALPS) where the body cannot control the number of immune cells (lymphocytes). This leads to enlarged lymph ...
Medical News Today - Thu, 14 May 2015 02:56



Riedel's thyroiditis and F18-FDG-PET scan
These results are consistent with an inflammatory/reactive process and not a lymphoproliferative disorder or an infiltrating carcinoma. An F-18 fluorodeoxyglucose (FDG) PET scan showed intense FDG avidity in the right thyroid mass without increased ...
Healio - Tue, 21 Apr 2015 12:20

New guidelines address primary cutaneous T-cell lymphoproliferative disorders
HOLLYWOOD, FLA. – The treatment of patients with lymphomatoid papulosis depends on the presentation, according to new National Comprehensive Cancer Network guidelines for managing primary cutaneous CD30+ T-cell lymphoproliferative disorders.
The Oncology Report - Wed, 16 Apr 2014 13:19

Higher Rates of Lymphoproliferative Disorders in Patients with Celiac Disease
A team of researchers recently investigated rates of various lymphoproliferative disorders in patients with celiac disease. The research team included L.A. Leslie, B. Lebwohl, A.I. Neugut, J. Gregory Mears, G. Bhagat, and P.H. Green. They are ...
Celiac.com - Mon, 30 Jul 2012 00:18

Celiac disease linked to lymphoproliferative disorders
(HealthDay) -- Patients with celiac disease, particularly those presenting with malabsorption symptoms later in life, have a higher incidence of lymphoproliferative disorders (LPDs), according to research published in the August issue of the American ...
Medical Xpress - Thu, 26 Jul 2012 09:41


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Last update: September 2014