Isavuconazole noninferior for invasive mold disease in hematologic malignancies
This substudy included 433 patients with underlying hematologic malignancies and possible, probable or proven invasive mold disease. The modified intent-to-treat analysis included only patients with probable or proven disease. Among the 217 patients ...
Healio - Mon, 15 Sep 2014 14:37

Adaptive Biotechnologies Announces the Formation of a Hematologic ...
Adaptive plans to work closely with the SAB to generate additional clinical evidence for the utility of clonoSEQ to measure relapse in patients with diseases such as Multiple Myeloma and Lymphoma, where MRD has traditionally been more difficult to ...
SYS-CON Media (press release) - Mon, 29 Sep 2014 08:47

Portola Pharmaceuticals Announces Proposed Offering of Common Stock
Portola Pharmaceuticals is a biopharmaceutical company developing product candidates that could significantly advance the fields of thrombosis and other hematologic diseases. The Company is advancing its three wholly-owned programs using novel ...
NASDAQ - Wed, 01 Oct 2014 13:26

Mesoblast Partner JCR Pharmaceuticals Files for Marketing Approval of the ...
According to the Center for International Blood and Marrow Transplant Research, there are approximately 30,000 allogeneic hematopoietic stem cell transplants (HSCT) globally per year for diseases including hematological cancers. Nearly 50% of these ...
NASDAQ - Tue, 30 Sep 2014 17:11

Five children with deletions of 1p34.3 encompassing AGO1 and AGO3
The effects of germline AGO variants or dosage alterations in humans are not known, however, prior studies have implicated dysregulation of the RNAi mechanism in the pathogenesis of several neurodevelopmental disorders. We describe five patients with ...
Nature.com - Wed, 01 Oct 2014 03:17



Crossing Therapeutic Boundaries: Molecular Profiling May Help Move ...
... essentially identical genetic mutation that characterizes the progression of the hematologic malignancy chronic myeloid leukemia (CML) and the solid tumor gastrointestinal stromal sarcoma (GIST). In these two vastly different malignant conditions ...
OncLive - Wed, 01 Oct 2014 06:41



A parent's worst nightmare: When a fever turns out to be cancer
But in some types of leukemia patients are asymptomatic said Michael Deininger, M.D., Ph.D., division of hematology and hematologic malignancies at Huntsman Cancer Institute at the University of Utah. Often a red flag isn't raised until blood counts ...
KSL.com - Tue, 30 Sep 2014 14:01

Impact of CD34 + cell dose in children who receive unrelated PBSCT with in ...
Excluding two patients with malignant disease who did not receive antibody-based T-cell depletion during conditioning, the final cohort consisted of 81 patients treated for hematologic malignancy (Table 1). Risk status at transplant was based on ...
Nature.com - Mon, 29 Sep 2014 07:55


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Last update: September 2014