Odanacatib Efficacy Stays Strong, Side Effects Give Pause
HOUSTON – Odanacatib (Merck), an investigational once-weekly oral highly selective cathepsin-K inhibitor, shows a robust effect in reducing fracture in postmenopausal women with osteoporosis in long-term phase 3 clinical-trial results. However, small ...
Medscape - Fri, 19 Sep 2014 12:26

Accused cop-shooter was confronted by deputies at his home over domestic ...
Police say Barthelemy and James Wilson, 26, shot a 28-year-old man in the neck as he left a house party around 1:35 a.m. in the 1300 block of Annette Street. The victim survived. Witnesses said the gunmen, who matched the descriptions of Barthelemy and ...
The Times-Picayune - NOLA.com - Thu, 18 Sep 2014 11:22

Suspects in shooting of NOPD officer accused of another shooting minutes earlier
Around 1:35 that same morning, a 28-year-old man was shot in the neck while leaving a party in the 1300 block of Annette Street, police said. According to police ... One bullet fractured his right femur and another lodged near his spine, police said ...
The Times-Picayune - NOLA.com - Wed, 17 Sep 2014 17:11

Bozeman man finishes marathon with fractured femur
Perhaps Jennifer Ford will just take her husband on a camping trip for Father's Day next year. “Whatever we do, it's going to have to be something really nice after this,” she joked Wednesday afternoon.
The Bozeman Daily Chronicle - Wed, 10 Sep 2014 22:48

Dual X-ray Absorptiometry for Diagnosis of Osteoporosis
A postmenopausal patient (white race; aged 69 years) was referred to the osteoporosis clinic after a screening dual-energy x-ray absorptiometry (DXA) scan showed low bone mineral density (BMD) of the spine (Table). She had no history of fractures or falls.
JAMA: The Journal of the American Medical Association - Tue, 16 Sep 2014 13:15



Leg-Stand Test Predicts Hip-Fracture Risk in Women
The women in the trial had a mean age of 59.1 years, and their measurements on functional capacity and femoral neck bone-mineral density (FN BMD) were available. At a mean follow-up of 13.1 years, 578 fractures were reported among the women, ...
Medscape - Sat, 13 Sep 2014 09:52

New Analyses Of Phase 2 Study Presented At ASBMR Show Romosozumab ...
THOUSAND OAKS, CA, USA and BRUSSELS, Belgium I September 15, 2014 I Amgen (NASDAQ: AMGN) and UCB (Euronext Brussels:UCB) today announced results from several exploratory analyses of the Phase 2 study evaluating romosozumab in ...
PipelineReview.com (press release) - Tue, 16 Sep 2014 00:56

Anti-inflammatory treatment could slow bone loss in early rheumatoid arthritis
Major finding: Average use of biologic disease-modifying antirheumatic drugs rose from 18.5% during the first 2 years to 62.6% during the next 8 years, while average bone loss slowed substantially (from –1.00% to –0.56% for the femoral neck, from –0.96 ...
Family Practice News Digital Network - Mon, 15 Sep 2014 08:11


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Last update: September 2014