Alexion Pharma's Soliris gets orphan drug status in Japan to treat patients ...
In patients with MG, uncontrolled complement activation due to antibodies directed at the neuromuscular junction can ultimately lead to profound and debilitating weakness of various muscle groups throughout the body. This significant muscle ... The ...
pharmabiz.com - Fri, 12 Dec 2014 21:26

Alexion Pharma (ALXN) Reports Soliris Award Orphan Drug Designation in Japan
In patients with MG, uncontrolled complement activation due to antibodies directed at the neuromuscular junction can ultimately lead to profound and debilitating weakness of various muscle groups throughout the body.1,2 This significant muscle weakness ...
StreetInsider.com (subscription) - Wed, 10 Dec 2014 14:11



What is ALS? The Real Challenge
Studies have linked 10 identifiable genes to ALS and other motor neuron diseases (including a mutation of the enzyme superoxide dismutase 1, found by Rozen and colleagues in 1993). Typical symptoms of upper motor neuron (UMNs) degeneration include ...
Brain Blogger (blog) - Fri, 05 Dec 2014 04:00



Researchers Identify New Rare Neuromuscular Disease
There are a number of disorders – both acquired and inherited – that interfere with the communication that occurs at the neuromuscular junction. For example, in Lambert-Eaton myasthenic syndrome, which is most commonly triggered by certain cancers, the ...
University of Rochester Newsroom - Thu, 04 Sep 2014 08:56

Rare Neuromuscular Disease Identified In American And British Family; Genetic ...
Medical Daily - Thu, 04 Sep 2014 09:08



Diagnosis and Management of Neuromuscular Disorders in Children
He then described several case histories, including two cases of familial neuromyotonia, autoimmune neuromuscular junction abnormality, toxic neuromuscular junction abnormality due to botulism, and the motor neuron diseases poliomyelitis and infantile ...
HCPLive - Mon, 13 Oct 2014 09:07



Gene therapy helps weak mice grow strong
Many of these diseases involve defective neuromuscular junctions—the interface between neurons and muscle cells where brain signals tell muscles to contract. In one such disease, a form of familial limb-girdle myasthenia, people carry two defective ...
Science AAAS - Thu, 18 Sep 2014 11:11

Local leaders raise money for muscular dystrophy
... friends and business contacts to make donations to your 'bail,' which are funds that will help the Muscular Dystrophy Association in its mission of curing muscular dystrophy, ALS (Lou Gehrig's disease) and related diseases by funding worldwide ...
Aiken Standard - Sun, 19 Oct 2014 18:15

Myasthenia gravis caused by muscle receptor antibodies
Answer • Myasthenia gravis is a disease of the neuromuscular junction, the point at which nerve cells communicate information to muscle cells. It is caused by antibodies to proteins in and around the muscle receptor for the chemical acetylcholine ...
STLtoday.com - Mon, 10 Nov 2014 21:03


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Last update: September 2014