Zebrafish as a Model to Investigate Dynamin 2-Related Diseases
... correlates of motility defects, we used monoclonal antibodies znp-1 and zn-5, and α-bungarotoxin (α-btx) staining to detect primary motor axons, secondary motor axon projections, and acetylcholine receptors (AChRs) at neuromuscular junctions ...
Nature.com - Thu, 04 Feb 2016 03:42

Australia Day Honours 2016: the full list
For eminent service to medicine, particularly to the discipline of paediatric neurology, through pioneering efforts in neuromuscular research, to a range of medical professional organisations at the national and international level, and as an author ...
Sydney Morning Herald - Mon, 25 Jan 2016 05:07

C9ORF72 Mice Point to Gain of Toxic Function in ALS, FTD
Eggan's group used electromyography to detect denervation at the neuromuscular junction in their animals, but came up with baffling results. They found denervation and reduced motor neuron counts in the first group of animals they assessed, but not in ...
Alzforum - Thu, 29 Oct 2015 19:34

GRHealth Unveils Roosevelt Warm Springs Capital Project Plans
Georgia State Representative Robert Trammell, D-Luthersville, thanked colleague Representative Debbie Buckner, D-Junction City, and Governor Nathan Deal for their tireless work in encouraging the state legislature to approve the budget and the general ...
WJBF-TV - Thu, 01 Oct 2015 10:15

Loss of tiny genetic molecules could play role in neurodegenerative diseases
In the paper, scientists at the Salk Institute report that animals unable to produce just one of many genetic molecules called microRNAs develop symptoms of devastating neurodegenerative diseases like amyotrophic lateral sclerosis (ALS or Lou Gehrig's ...
Medical Xpress - Thu, 17 Dec 2015 11:02

Sachdev to lead new MSU Division of Neuromuscular Medicine
Neuromuscular diseases affect many body areas including the autonomic nervous system, spinal cord, nerve root, peripheral nerve, nerve-muscle junction and muscle. Diseases include ALS, radiculopathy, neuropathy and Guillain-Barré syndrome. Others ...
MSUToday - Thu, 27 Aug 2015 06:38

Catalyst Pharma finishes rolling Firdapse NDA submission for ultra-rare diseases
LEMS is an autoimmune disorder characterized by muscle weakness in the arms and legs caused by the buildup of antibodies at the connection between nerve and muscle (neuromuscular junction). It commonly strikes people over the age of 40 and is ...
Seeking Alpha - Thu, 17 Dec 2015 06:03

Neuroscientists reveal how the brain can enhance connections
To investigate how synapses are strengthened, Littleton and Cho studied a type of synapse known as neuromuscular junctions, in fruit flies. The researchers stimulated the presynaptic neurons with a rapid series of action potentials over a short period ...
Medical Xpress - Wed, 18 Nov 2015 09:01

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