Comprehensive genomic profiling of orbital and ocular adnexal lymphomas ...
Orbital and ocular adnexal lymphomas are B-cell proliferations that include low-grade tumors such as extra-nodal marginal zone (also known as mucosa-associated lymphoid tissue lymphoma (MALT)) and follicular lymphoma, as well as high-grade tumors ...
Nature.com - Fri, 22 Apr 2016 04:37



Semaphorin 7a exerts pleiotropic effects to promote breast tumor progression
In mice, Sem7a expression is observed at high levels in the brain, spinal cord, lung, testis, bone and spleen as well as in immune cells; in human tissues, Sem7a expression has been observed in the nervous system, odontoblasts, fibroblasts ...
Nature.com - Mon, 11 Apr 2016 06:59

Glioblastoma Multiforme Treatment Market - GBM Is Boosting the Diagnostic Rate
Glioblastoma multiforme (GBM) is a high-grade gliomas and the most malignant astrocytic tumor, composed of complexly differentiated neoplastic astrocytes, a subtype of central nervous system (CNS). Glioblastoma is clinically classified as grade IV ...
Digital Journal - Fri, 15 Apr 2016 08:33



Vaccine Therapy, Oncolytic Viruses, and Gliomas
Given at sufficient doses, radiation therapy can eradicate almost all neoplastic cells, but unfortunately, the curative potential of this therapy is limited by a low therapeutic index in the nervous system. The damage to normal tissue within the ...
Cancer Network - Wed, 16 Mar 2016 14:43



Prolyl-isomerase Pin1 controls Notch3 protein expression and regulates T-ALL ...
Together, our findings demonstrate that Pin1–Notch3 axis may reinforce Notch signaling effect in T-ALL, by influencing tumor grade and aggressiveness, finally suggesting that their combined inhibition may be exploited in target therapy protocols ...
Nature.com - Mon, 15 Feb 2016 03:42



Blocking inflammation prevents cell death, improves memory in Alzheimer's disease
In healthy tissue, microglia act as the first and main form of immune defense in the central nervous system. But in a disease state, such as Alzheimer's, microglia appear to turn against the healthy tissue they were originally assigned to protect ...
Science Daily - Wed, 02 Mar 2016 10:03



Single sternal metastasis due to malignant melanoma with unexpected long-term ...
1Thoracic Surgery Department, 2Department of Pathology, Theagenio Cancer Hospital, Thessaloniki, 3Nuclear Medicine Department, University General Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupolis, 4Pulmonary Department ...
Dove Medical Press - Mon, 18 Jan 2016 13:56

Flu season begins, but experts say this year's vaccine should do the trick
Also, some patients who have autoimmune diseases or take certain medications for cancer cannot be vaccinated and are more vulnerable to influenza. The flu vaccine is available at no cost through most insurance plans, including Medicare Part B. Those ...
San Jose Mercury News - Wed, 30 Sep 2015 09:06


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