MRI accurate in diagnosing primary biliary cirrhosis, liver fibrosis
Twenty-five patients showed signs of periportal hyperintensity, eight patients showed stage I and stage II homogeneous liver signal intensity, and 25 patients had non-homogeneous liver signal changes, based on MRI. A positive correlation was observed ...
Healio - Tue, 24 Mar 2015 10:48

Finding the Patient With Primary Biliary Cirrhosis
The presentation of PBC can range from an abnormal serum alkaline phosphatase level in an asymptomatic person to unexplained pruritus, overt jaundice, or an initial presentation with advanced liver disease. Pruritus and fatigue are early symptoms that ...
Medscape - Fri, 27 Feb 2015 07:26



Obeticholic acid decreased ALP, ALT levels in patients with primary biliary ...
Obeticholic acid effectively decreased alanine aminotransferase, gamma-glutamyl transpeptidase and alkaline phosphatase levels compared with placebo, in patients with primary biliary cirrhosis who failed previous therapy with ursodeoxycholic acid ...
Healio - Fri, 13 Mar 2015 08:54



Intercept Pharmaceuticals Inc. (NASDAQ:ICPT) announced new subgroup ...
Obeticholic acid (OCA) is a first-in-class farnesoid X receptor (FXR) agonist being developed for primary biliary cirrhosis (PBC), NASH and other chronic liver indications. Intercept has initiated a rolling New Drug Application with the FDA for PBC ...
Inside Trade - Fri, 27 Mar 2015 05:56

Biotech Beat: 3/26/15 - Intercept Pharmaceuticals (ICPT)
Seeking Alpha (registration) - Fri, 27 Mar 2015 02:56

Inside Scoop on Intercept Pharmaceuticals Inc (NASDAQ:ICPT)
Investor Newswire - Fri, 27 Mar 2015 08:45



Asklepion : FDA Okays Cholbam To Treat Rare Bile Acid Synthesis Disorders
The Warnings and Precautions for Cholbam include worsening liver disease and biliary obstruction. Adverse reactions include a 2 percent incidence of diarrhea, and 1 percent incidence of abdominal pain, nausea, intestinal polyp, reflux esophagitis ...
RTT News - Tue, 17 Mar 2015 18:31

CHOLBAM (cholic acid) Now Approved In The U.S. For Patients With Bile Acid ...
SYS-CON Media (press release) - Tue, 17 Mar 2015 17:33



Georgetown student uses personal struggle to empower others
Born with biliary atresia, a rare liver disease, Ciesemier hasn't always been able to live so freely. After undergoing two liver transplants, Ciesemier watched a segment about African AIDS orphans on the Oprah Winfrey Show and decided to use her ...
USA TODAY College - Thu, 26 Mar 2015 06:31

Potential NAFLD drug safely reduces ALT, cCK18 levels
In a phase 2 clinical trial, emricasan successfully reduced alanine aminotransferase and other serum levels in patients with nonalcoholic fatty liver disease, as well as a subgroup of patients with nonalcoholic fatty liver disease who also had ...
Healio - Thu, 26 Mar 2015 11:45

You're never too old to be an organ donor
She had the liver disease biliary atresia and had only months to live when she received a transplant just before her first birthday. "The liver she received was from an adult, and as we understand it, she received a part and another adult received a ...
NEWS.com.au - Wed, 25 Mar 2015 19:15


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Last update: September 2014