Hyperbilirubinemia Does Not Influence Persistence with Atazanavir Treatment
PHILADELPHIA, PA—Hyperbilirubinemia does not appear to influence persistence with atazanavir (ATV) in a “real-world setting,” results of a retrospective analysis reported at IDWeek 2014 have found. To determine whether patients with HIV have poor ...
Monthly Prescribing Reference - Sat, 11 Oct 2014 08:56



Bucks County firm raises $750K to advance jaundice treatment for infants
The Trevose, Pa., company's lead product, called Stanate, is being developed as a potential treatment for infants with jaundice, also known as hyperbilirubinemia. The condition, the result of increased serum bilirubin levels, causes a yellowing of the ...
Philadelphia Business Journal (blog) - Thu, 23 Oct 2014 05:56

Sustained inhibition of hepatitis B virus replication in vivo using RNAi ...
Lifelong elimination of hyperbilirubinemia in the Gunn rat with a single injection of helper-dependent adenoviral vector. Proc Natl Acad Sci USA 2005; 102: 3930–3935. | Article | PubMed | CAS |; Mingozzi F, High KA. Therapeutic in vivo gene transfer ...
Nature.com - Thu, 23 Oct 2014 03:16

Long-term Treatment Success Using Gene Therapy to Correct a Lethal ...
In “Life-Long Correction of Hyperbilirubinemia with a Neonatal Liver-Specific AAV-Mediated Gene Transfer in a Lethal Mouse Model of Crigler–Najjar Syndrome,” Giulia Bortolussi and coauthors from the International Centre for Genetic Engineering and ...
HealthCanal.com - Thu, 09 Oct 2014 07:26

HIV: Non-Efavirenz Regimens Effective in Initial Treatment
"Among [protease inhibitor (PI)]-containing regimens, ritonavir-boosted darunavir was better tolerated than ritonavir-boosted atazanavir, primarily because of differences in hyperbilirubinemia." Guidelines from both the World Health Organization and ...
Medscape - Fri, 10 Oct 2014 14:56



The Changing HCV Landscape:
Adverse events associated with simeprevir included hyperbilirubinemia related to interactions with transporters but no actual hepatotoxicity; a slight increase in photosensitivity; and in one study, mild pruritus. No additional hemoglobin decline was ...
Gastroenterology & Endoscopy News - Fri, 17 Oct 2014 12:52

Overdiagnosis in Pediatric Care? Defining, Gauging the Problem
They also list examples of overdiagnosis in attention deficit/hyperactivity disorder, bacteremia, hyperbilirubinemia, and other disorders. Overdiagnosis can be harmful in terms of physical effects, psychological effects, financial strain, and ...
Medscape - Wed, 08 Oct 2014 23:21

Long-term success using gene therapy to fix lethal metabolic disorder
... University of Trieste (Trieste, Italy) and Charles University (Prague, Czech Republic), present details of the adeno-associated virus (AAV)-mediated gene therapy approach they used to correct the metabolic disorder that causes hyperbilirubinemia in ...
Science Codex - Mon, 13 Oct 2014 11:22


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Last update: September 2014