Hyperbilirubinemia Does Not Influence Persistence with Atazanavir Treatment
PHILADELPHIA, PA—Hyperbilirubinemia does not appear to influence persistence with atazanavir (ATV) in a “real-world setting,” results of a retrospective analysis reported at IDWeek 2014 have found. To determine whether patients with HIV have poor ...
Monthly Prescribing Reference - Sat, 11 Oct 2014 08:56



The Changing HCV Landscape:
Adverse events associated with simeprevir included hyperbilirubinemia related to interactions with transporters but no actual hepatotoxicity; a slight increase in photosensitivity; and in one study, mild pruritus. No additional hemoglobin decline was ...
Gastroenterology & Endoscopy News - Fri, 17 Oct 2014 12:52

HIV: Non-Efavirenz Regimens Effective in Initial Treatment
"Among [protease inhibitor (PI)]-containing regimens, ritonavir-boosted darunavir was better tolerated than ritonavir-boosted atazanavir, primarily because of differences in hyperbilirubinemia." Guidelines from both the World Health Organization and ...
Medscape - Fri, 10 Oct 2014 14:56

Long-term Treatment Success Using Gene Therapy to Correct a Lethal ...
In “Life-Long Correction of Hyperbilirubinemia with a Neonatal Liver-Specific AAV-Mediated Gene Transfer in a Lethal Mouse Model of Crigler–Najjar Syndrome,” Giulia Bortolussi and coauthors from the International Centre for Genetic Engineering and ...
HealthCanal.com - Thu, 09 Oct 2014 07:26

Long-term success using gene therapy to fix lethal metabolic disorder
... University of Trieste (Trieste, Italy) and Charles University (Prague, Czech Republic), present details of the adeno-associated virus (AAV)-mediated gene therapy approach they used to correct the metabolic disorder that causes hyperbilirubinemia in ...
Science Codex - Mon, 13 Oct 2014 11:22

Overdiagnosis in Pediatric Care? Defining, Gauging the Problem
They also list examples of overdiagnosis in attention deficit/hyperactivity disorder, bacteremia, hyperbilirubinemia, and other disorders. Overdiagnosis can be harmful in terms of physical effects, psychological effects, financial strain, and ...
Medscape - Wed, 08 Oct 2014 23:21

Detecting jaundice in babies? There could be an app for that
Bilirubin passes through the liver on its way out of the body. When levels of bilirubin in the blood are high (a condition known as hyperbilirubinemia), it might mean there's a problem with the liver. When levels become extremely high, patients develop ...
WNAX - Mon, 22 Sep 2014 21:18

Chimerix's (CMRX) CEO Michelle Berrey Hosts R&D Update (Transcript) (CMRX)
He had half the Brincidofovir held due to some hyperbilirubinemia due to more conazole, which resulted in worsening of his viral load. And at the same time he also was felt to have some diarrhea related to Brincidofovir and after negotiation with the ...
Seeking Alpha (registration) - Wed, 15 Oct 2014 22:03


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Last update: September 2014