SAPPHIRE-I, II: Treatment sustained despite hyperbilirubinemia in some HCV ...
WASHINGTON, D.C. — Elevated bilirubin levels were detected in some patients with hepatitis C virus assigned three direct-acting antivirals plus ribavirin, but none discontinued treatment, according to data presented at ICAAC 2014.
Healio - Wed, 10 Sep 2014 12:26

Still Jaundiced After All These Weeks: The Breastfed Neonate
To learn more about the natural history of jaundice in the healthy breastfed infant and determine the prevalence of prolonged hyperbilirubinemia in a US population of infants, Maisels and colleagues measured transcutaneous bilirubin (TcB) levels in a ...
Medscape - Tue, 19 Aug 2014 11:11

Rivaroxaban and Liver Injury: Case Studies Add to Safety Questions
Observations: We report 2 patients with predominantly hepatocellular liver injury that had onset during treatment with rivaroxaban. Both were symptomatic, had massively elevated transaminase activity levels and hyperbilirubinemia, and fulfilled the ...
Monthly Prescribing Reference - Fri, 29 Aug 2014 10:26

Exelixis Announces Results from the COMET-1 Phase 3 Pivotal Trial of ...
SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Sep. 1, 2014-- Exelixis, Inc. (NASDAQ:EXEL) today announced top-line results from the final analysis of COMET-1, the phase 3 pivotal trial of cabozantinib in men with metastatic castration-resistant ...
FiercePharma - Mon, 01 Sep 2014 14:56

Top Liver Abstracts From 2014 DDW and EASL
The safety data from PEARL-II and -IV demonstrate incremental incidences of fatigue, nausea, hemoglobin reduction and hyperbilirubinemia with RBV, with very low rates of discontinuation for AEs, and are entirely consistent with historical experience.
Gastroenterology & Endoscopy News - Thu, 21 Aug 2014 21:07


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Last update: September 2014