Hyperbilirubinemia Does Not Influence Persistence with Atazanavir Treatment
PHILADELPHIA, PA—Hyperbilirubinemia does not appear to influence persistence with atazanavir (ATV) in a “real-world setting,” results of a retrospective analysis reported at IDWeek 2014 have found. To determine whether patients with HIV have poor ...
Monthly Prescribing Reference - Sat, 11 Oct 2014 08:56



Bucks County firm raises $750K to advance jaundice treatment for infants
The Trevose, Pa., company's lead product, called Stanate, is being developed as a potential treatment for infants with jaundice, also known as hyperbilirubinemia. The condition, the result of increased serum bilirubin levels, causes a yellowing of the ...
Philadelphia Business Journal (blog) - Thu, 23 Oct 2014 05:56

Acute organ failure following the loss of anti-apoptotic cellular FLICE ...
Loss of cFLIP resulted in acute liver failure characterized hypoglycemia and hyperbilirubinemia, and was accompanied by depletion of intrahepatic leukocytes and the activation of inflammatory macrophages. All mice died within 96 h. Interestingly, this ...
Nature.com - Fri, 24 Oct 2014 04:58

Sustained inhibition of hepatitis B virus replication in vivo using RNAi ...
Lifelong elimination of hyperbilirubinemia in the Gunn rat with a single injection of helper-dependent adenoviral vector. Proc Natl Acad Sci USA 2005; 102: 3930–3935. | Article | PubMed | CAS |; Mingozzi F, High KA. Therapeutic in vivo gene transfer ...
Nature.com - Thu, 23 Oct 2014 03:16

Long-term Treatment Success Using Gene Therapy to Correct a Lethal ...
In “Life-Long Correction of Hyperbilirubinemia with a Neonatal Liver-Specific AAV-Mediated Gene Transfer in a Lethal Mouse Model of Crigler–Najjar Syndrome,” Giulia Bortolussi and coauthors from the International Centre for Genetic Engineering and ...
HealthCanal.com - Thu, 09 Oct 2014 07:26

HIV: Non-Efavirenz Regimens Effective in Initial Treatment
"Among [protease inhibitor (PI)]-containing regimens, ritonavir-boosted darunavir was better tolerated than ritonavir-boosted atazanavir, primarily because of differences in hyperbilirubinemia." Guidelines from both the World Health Organization and ...
Medscape - Fri, 10 Oct 2014 14:56



The Changing HCV Landscape:
Adverse events associated with simeprevir included hyperbilirubinemia related to interactions with transporters but no actual hepatotoxicity; a slight increase in photosensitivity; and in one study, mild pruritus. No additional hemoglobin decline was ...
Gastroenterology & Endoscopy News - Fri, 17 Oct 2014 12:52

Long-term success using gene therapy to fix lethal metabolic disorder
... University of Trieste (Trieste, Italy) and Charles University (Prague, Czech Republic), present details of the adeno-associated virus (AAV)-mediated gene therapy approach they used to correct the metabolic disorder that causes hyperbilirubinemia in ...
Science Codex - Mon, 13 Oct 2014 11:22


1  2  3  4  5  6  7  8    ->


We do not evaluate or guarantee the accuracy of any content in this site. Click here for the full disclaimer.

Last update: September 2014