Hyperalgesia May Be Reversible After Spinal Pain Pathway Reactivation
Research using an animal model of pain suggests that mechanical hyperalgesia may be reversible in mice after spinal pain pathways are reactivated in a manner analogous to memory reconsolidation. This previously unobserved regulatory mechanism ...
HCPLive - Thu, 02 Oct 2014 17:56

Mayor's summit on prescription drug abuse educates local leaders
When patients receive narcotics for long periods, they can even become more sensitive to pain, a condition called hyperalgesia. (J. David Haddox, the vice-president of health policy at Purdue Pharma—the manufacturer of OxyContin—acknowledged “opioid ...
Tulsa World - Fri, 17 Oct 2014 14:14



Diagnosis and Management of Pediatric Amplified Musculoskeletal Pain
The work up includes past medical history, social history, physical examination, autonomic signs, tests for allodynia and hyperalgesia and laboratory tests and imaging to exclude a physical cause. Hoffart stressed the importance of evaluating the ESR ...
HCPLive - Mon, 13 Oct 2014 13:25

Inflammatory and oxidative and nitrosative stress cascades as new drug targets ...
Patients with ME and CFS show higher scores on fatigue, neurocognitive disorders, hyperalgesia, autonomic symptoms, postexertional malaise and a subjective feeling of infection than patients with CF. ME is characterized by increased postexertional ...
ProHealth - Wed, 01 Oct 2014 00:07



ADA 2014: Pain management and addiction -- the dentist's role
Dr. Lindroth explained the two types of pain: albdynia, in which a light touch is painful, like sunburn; and hyperalgesia, in which pain is exaggerated, like slapping the back of a sunburned person or pulp testing a tooth, which causes patients to ...
DrBicuspid.com - Tue, 14 Oct 2014 00:01

Hypersensitivity to non-painful events may be part of pathology in fibromyalgia
New research shows that patients with fibromyalgia have hypersensitivity to non-painful events based on images of the patients' brains, which show reduced activation in primary sensory regions and increased activation in sensory integration areas ...
Medical Xpress - Sun, 14 Sep 2014 21:07

Are Flawed Dose Conversion Calculators to Blame for the Dramatic Increase in ...
For example, opioids may be switched when pain is not under control and doses cannot be escalated, when adverse events or toxicity occurs, when patients develop rapid tolerance, or when opioid-induced hyperalgesia is suspected. Specifically in chronic ...
HCPLive - Mon, 22 Sep 2014 09:18



Solving the painkiller crisis: It's in the hands of doctors
In fact, such therapy can also cause pain rather than relieve it – a condition known as opioid-induced hyperalgesia. For reasons scientists don't fully understand, the central nervous system becomes overly sensitive. When patients complain that their ...
The Globe and Mail - Fri, 03 Oct 2014 15:50


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Last update: September 2014