Hyperalgesia May Be Reversible After Spinal Pain Pathway Reactivation
Research using an animal model of pain suggests that mechanical hyperalgesia may be reversible in mice after spinal pain pathways are reactivated in a manner analogous to memory reconsolidation. This previously unobserved regulatory mechanism ...
HCPLive - Thu, 02 Oct 2014 17:56

TRPV1 antagonist attenuates postoperative hypersensitivity by central and ...
Results: Plantar incision induced mechanical allodynia and hyperalgesia and thermal hyperalgesia. A single intrathecal administration of SB366791 significantly reduced postincisional thermal hyperalgesia and also attenuated mechanical allodynia, while ...
7thSpace Interactive (press release) - Mon, 17 Nov 2014 15:48

Is Opioid-Induced Hyperalgesia a Real Phenomenon?
Gudin, Director of Pain Management, Englewood Hospital and Medical Center, Englewood, NJ, described opioid-induced hyperalgesia (OIH) as dramatically increased sensitivity to painful stimuli or pain elicited by nonpainful stimulus following treatment ...
HCPLive - Sat, 20 Sep 2014 09:30

Woman recovering from $100K/month addiction turns to "miracle" treatments
Dr. James Flowers, Pain Recovery Program Director at Memorial Hermann PaRC, said, "She was experiencing something called hyperalgesia, where we take so much pain medication, that our brain actually begins to believe that our body is in more pain ...
KTRK-TV - Wed, 12 Nov 2014 20:17

Gwyneth Paltrow is right: there is a "secret organ" you've been ignoring
"The fascia around those muscles gets hypersensitive so the nerves that serve that area create something called hyperalgesia, or increased pain sensitivity," said Fleming. Because the fascia fibers run in many directions, one review of the evidence ...
Vox - Sat, 08 Nov 2014 06:03

The New Heroin Epidemic
For those who live, one perverse side effect of long-term opioid abuse is hyperalgesia—an increased sensitivity to pain. Over the past couple of years, though, the prescription frenzy seems to have subsided slightly, partly thanks to a slow ...
The Atlantic - Thu, 30 Oct 2014 05:00

Pain in Osteoarthritis
Following the development of osteoarthritis, increased sensitivity to load bearing and to normal movement of the joint can be experienced (allodynia), as well as increased sensitivity to further noxious stimulation (hyperalgesia). Under these ...
Brain Blogger (blog) - Thu, 13 Nov 2014 16:56

Opioid Tolerance or Hyperalgesia? Key Symptoms Offer Clues
Concerns about hyperalgesia as opioid overuse in general faces intense public and regulatory scrutiny were evident from the overflowing crowd spilling out into a hallway at the meeting to hear Dr. Silverman address the issue here at PAINWeek 2013.
Medscape - Mon, 16 Sep 2013 06:47

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Last update: September 2014