Hyperalgesia May Be Reversible After Spinal Pain Pathway Reactivation
Research using an animal model of pain suggests that mechanical hyperalgesia may be reversible in mice after spinal pain pathways are reactivated in a manner analogous to memory reconsolidation. This previously unobserved regulatory mechanism ...
HCPLive - Thu, 02 Oct 2014 17:56

Is Opioid-Induced Hyperalgesia a Real Phenomenon?
Gudin, Director of Pain Management, Englewood Hospital and Medical Center, Englewood, NJ, described opioid-induced hyperalgesia (OIH) as dramatically increased sensitivity to painful stimuli or pain elicited by nonpainful stimulus following treatment ...
HCPLive - Sat, 20 Sep 2014 09:30

Fibromyalgia Pain Type: Hyperalgesia
The most common kind of fibromyalgia pain, and the best researched, is hyperalgesia. "Hyper" means excess and "algesia" means pain. Hyperalgesia is the medical term for pain amplification in FMS. Our brains appear to take normal pain signals and "turn ...
About - News & Issues - Wed, 07 May 2014 04:04

Complex Regional Pain Syndrome: Pathophysiology, Diagnosis, and Treatment
Patients with either type may exhibit symptoms such as burning pain, hyperalgesia, and/or allodynia with an element of musculoskeletal pain. CRPS can be distinguished from other types of neuropathic pain by the presence of regional spread as opposed to ...
Pain Medicine News - Wed, 10 Dec 2014 06:26

Humboldt County's 'shocking' painkiller prescription rates reverse course
Hypersensitivity takes two forms: allodyinia, which is a painful response to something as innocuous as a shirt sleeve touching the arm, or hyperalgesia, an increased response to a painful stimulus such as a needle. Meengs said both problems are ...
Eureka Times Standard - Sun, 07 Dec 2014 16:00

Opioid Tolerance or Hyperalgesia? Key Symptoms Offer Clues
Concerns about hyperalgesia as opioid overuse in general faces intense public and regulatory scrutiny were evident from the overflowing crowd spilling out into a hallway at the meeting to hear Dr. Silverman address the issue here at PAINWeek 2013.
Medscape - Mon, 16 Sep 2013 06:47

Intrathecal injection of fluorocitric acid inhibits the activation of glial ...
Thermal hyperalgesia and mechanical hypersensitivity were measured for both groups to determine if the SNL model had Mirror image of Pain (MIP). Nav1.7 protein expression in DRG was analyzed using immunohistochemistry and western-blotting.
7thSpace Interactive (press release) - Mon, 15 Dec 2014 11:18

No association of polymorphisms in the serotonin transporter gene with thermal ...
There was also no difference in capsaicin-evoked ongoing pain and secondary hyperalgesia between the two genotype groups (p >0.4), also when subdivided by gender (p >0.17). In addition, there were no significant differences in the perception of the ...
7thSpace Interactive (press release) - Thu, 04 Dec 2014 01:45

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Last update: September 2014