My view: Medical marijuana: Google vs. PubMed
“Lack of Analgesia by Oral Standardized Cannabis Extract on Acute Inflammatory Pain and Hyperalgesia in Volunteers,” published in the Journal of the American Society of Anesthesiologists in 2008, found that “high doses of cannabinoids may even cause ...
Deseret News - Thu, 11 Feb 2016 23:05

Endogenous inhibition of pain and spinal nociception in women with ...
Purpose: Premenstrual dysphoric disorder (PMDD) is characterized by severe affective and physical symptoms, such as increased pain, during the late-luteal phase of the menstrual cycle. The mechanisms underlying hyperalgesia in women with PMDD have ...
Dove Medical Press - Thu, 11 Feb 2016 17:07



Blocking a Stress-Related Gene Relieves Chronic Pain
“This study suggests that changes in the glucocorticoid system and FKBP51 in the neurons of the spinal cord contribute to the switch from analgesia to hyperalgesia—or hypersensitivity to pain—and to the development of chronic pain,” said Samuel ...
The Scientist - Wed, 10 Feb 2016 11:26

Efficacy of pain treatment may be seen on MRI
Wanigasekera and colleagues studied images collected from 24 healthy individuals who underwent capsaicin-induced mechanical punctate hyperalgesia. Three study visits 1 week apart were conducted during which participants were screened and received ...
Healio - Tue, 09 Feb 2016 09:43



New Technique Shows Promise as Adjunct In Chronic Pain Management
Stress and the release of stress hormones play a role in the development of CS because they generate hyperalgesia and chronic pain through both peripheral and central mechanisms. Peripherally, catecholamines secreted by the adrenal medulla cause ...
PracticalPainManagement.com - Tue, 09 Feb 2016 11:18

Hyperalgesia Pipeline and 2015 Hyperalgesia Market Global Clinical Trials ...
The Hyperalgesia - Pipeline Review, H2 2015 market research report provides an overview of the Hyperalgesia's therapeutic pipeline and comprehensive information on comparative analysis at various stages, therapeutics assessment by drug target, ...
PR Newswire (press release) - Fri, 02 Oct 2015 05:37



Functional Imaging Beneficial for Analgesic Drug Development
The researchers found that suppression of the secondary mechanical hyperalgesia-evoked neural response in right nucleus cuneiformis and left posterior insular cortex and secondary somatosensory cortex was seen with gabapentin only. During central ...
Doctors Lounge - Fri, 12 Feb 2016 10:00



Experimental arthritis A chilling link to joint pain and hypersensitivity
... cation channel subfamily A member 1), a cold-sensing, calcium-permeable channel expressed in neurons, fibroblasts and cells of the immune system, as a component of mechanonociception and cold-induced hyperalgesia in a mouse model of arthritis.
Nature.com - Thu, 28 Jan 2016 21:15


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Last update: September 2014