Mild adrenal steroidogenic defects common in patients with high BP
“Is ACTH the driving stimulus regarding primary hyperaldosteronism? Is it possible to establish a continuum between hyperplasia and adenoma in primary hyperaldosteronism? Is stress-related high BP associated with ACTH-dependent aldosterone secretion ...
Healio - Fri, 26 Dec 2014 13:20

Aldosterone-Renin Ratio in the Assessment of Primary Aldosteronism
A middle-aged patient with diabetes and hypertension presented to his primary care physician for regular health assessment. His blood pressure was 183/116 mm Hg despite taking lisinopril (40 mg/d) and verapamil (180 mg/d). He had previously taken ...
JAMA_ The Journal of the American Medical Association - Tue, 08 Jul 2014 13:09

Expert examines contribution of aldosterone in obesity-related hypertension
Majewski also stressed that obesity-related hyperaldosteronism is different than true primary hyperaldosteronism. Guidelines from The Endocrine Society recommend that screening for primary hyperaldosteronism occur in patients with hypertension and ...
Healio - Fri, 24 Oct 2014 13:09

GSK announces 14 winners of Discovery Fast Track Challenge
Morris Brown, University of Cambridge (UK): Primary hyperaldosteronism; Dr. Federica Briani, Università degli Studi di Milano (Italy): Targeting bacterial infections; Dr. Christos Chatziantoniou, National Institute of Health and Medical Research ...
MedCity News - Mon, 01 Dec 2014 03:51

GSK names drug hunter challenge winners
PMLiVE - Tue, 02 Dec 2014 03:35

Winners of GSK Discovery Fast Track Challenge Announced
Genetic Engineering & Biotechnology News - Mon, 01 Dec 2014 11:07

Estrogen May Protect Heart by Inhibiting Mineralocorticoid
Several anti-mineralocorticoid diuretics have been approved and are used to treat chronic heart failure, hypertension and a condition known as hyperaldosteronism. "These drugs act on the mineralocorticoid receptor in the kidneys to lower blood pressure ...
MedPage Today - Sun, 09 Nov 2014 12:05

Severe Sleep Apnea Linked to Resistant Hypertension
Severe obstructive sleep apnea may interfere with blood pressure (BP)–lowering treatment in patients at high cardiovascular disease risk or with established cardiovascular disease, results of a multicenter clinical trial suggest. Doctors should ...
Medscape - Thu, 02 Oct 2014 13:56

Blood-Pressure Control Continues 3 Years' Postadrenalectomy
BOSTON — Blood-pressure control with or without medications was maintained for an average of 3 years in most patients who underwent adrenalectomy for primary hyperaldosteronism (PA) at 2 US endocrine surgery centers. These are the first long-term ...
Medscape - Mon, 05 May 2014 08:11

Higher Aldosterone Linked to Increased Parathyroid Hormone Levels
Data linked higher aldosterone with higher PTH (P<.0001) — a finding that was most pronounced in participants with primary hyperaldosteronism-like phenotype. The researchers noted a stepwise increment in PTH when comparing untreated participants ...
Endocrinology Advisor - Fri, 05 Dec 2014 13:00

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Last update: September 2014