|Mild adrenal steroidogenic defects common in patients with high BP|
“Is ACTH the driving stimulus regarding primary hyperaldosteronism? Is it possible to establish a continuum between hyperplasia and adenoma in primary hyperaldosteronism? Is stress-related high BP associated with ACTH-dependent aldosterone secretion ...
Healio - Fri, 26 Dec 2014 13:20
|Aldosterone-Renin Ratio in the Assessment of Primary Aldosteronism|
A middle-aged patient with diabetes and hypertension presented to his primary care physician for regular health assessment. His blood pressure was 183/116 mm Hg despite taking lisinopril (40 mg/d) and verapamil (180 mg/d). He had previously taken ...
JAMA_ The Journal of the American Medical Association - Tue, 08 Jul 2014 13:09
|Expert examines contribution of aldosterone in obesity-related hypertension|
Majewski also stressed that obesity-related hyperaldosteronism is different than true primary hyperaldosteronism. Guidelines from The Endocrine Society recommend that screening for primary hyperaldosteronism occur in patients with hypertension and ...
Healio - Fri, 24 Oct 2014 13:09
|GSK announces 14 winners of Discovery Fast Track Challenge|
Morris Brown, University of Cambridge (UK): Primary hyperaldosteronism; Dr. Federica Briani, Università degli Studi di Milano (Italy): Targeting bacterial infections; Dr. Christos Chatziantoniou, National Institute of Health and Medical Research ...
MedCity News - Mon, 01 Dec 2014 03:51
|GSK names drug hunter challenge winners|
PMLiVE - Tue, 02 Dec 2014 03:35
|Winners of GSK Discovery Fast Track Challenge Announced|
Genetic Engineering & Biotechnology News - Mon, 01 Dec 2014 11:07
|Estrogen May Protect Heart by Inhibiting Mineralocorticoid|
Several anti-mineralocorticoid diuretics have been approved and are used to treat chronic heart failure, hypertension and a condition known as hyperaldosteronism. "These drugs act on the mineralocorticoid receptor in the kidneys to lower blood pressure ...
MedPage Today - Sun, 09 Nov 2014 12:05
|Severe Sleep Apnea Linked to Resistant Hypertension|
Severe obstructive sleep apnea may interfere with blood pressure (BP)–lowering treatment in patients at high cardiovascular disease risk or with established cardiovascular disease, results of a multicenter clinical trial suggest. Doctors should ...
Medscape - Thu, 02 Oct 2014 13:56
|Blood-Pressure Control Continues 3 Years' Postadrenalectomy|
BOSTON — Blood-pressure control with or without medications was maintained for an average of 3 years in most patients who underwent adrenalectomy for primary hyperaldosteronism (PA) at 2 US endocrine surgery centers. These are the first long-term ...
Medscape - Mon, 05 May 2014 08:11
|Higher Aldosterone Linked to Increased Parathyroid Hormone Levels|
Data linked higher aldosterone with higher PTH (P<.0001) — a finding that was most pronounced in participants with primary hyperaldosteronism-like phenotype. The researchers noted a stepwise increment in PTH when comparing untreated participants ...
Endocrinology Advisor - Fri, 05 Dec 2014 13:00