Genetics of adrenal diseases in 2014: Genetics improves understanding of ...
Namely, adenomas and hyperaldosteronism in Conn syndrome, tumours associated with adrenal Cushing syndrome, adrenocortical carcinomas and familial phaeochromocytoma and/or paraganglioma syndromes. Specific and different signalling pathways ... - Mon, 15 Dec 2014 23:09

Cambridge dominates GSK medical discovery challenge
The Cambridge winners of the GSK Discovery Fast Track Challenge are Professor Steve Jackson and Dr Delphine Larrieu, for their work in the treatment of inherited laminopathies; Professor Morris Brown, in the field of primary hyperaldosteronism; and ...
Business Weekly - Wed, 03 Dec 2014 01:45

GSK Names Winners of 2014 Discovery Fast Track Challenge (press release) - Mon, 01 Dec 2014 01:56

Higher Aldosterone Linked to Increased Parathyroid Hormone Levels
Data linked higher aldosterone with higher PTH (P<.0001) — a finding that was most pronounced in participants with primary hyperaldosteronism-like phenotype. The researchers noted a stepwise increment in PTH when comparing untreated participants ...
Endocrinology Advisor - Fri, 05 Dec 2014 13:00

Expert examines contribution of aldosterone in obesity-related hypertension
Majewski also stressed that obesity-related hyperaldosteronism is different than true primary hyperaldosteronism. Guidelines from The Endocrine Society recommend that screening for primary hyperaldosteronism occur in patients with hypertension and ...
Healio - Fri, 24 Oct 2014 13:09

Estrogen May Protect Heart by Inhibiting Mineralocorticoid
Several anti-mineralocorticoid diuretics have been approved and are used to treat chronic heart failure, hypertension and a condition known as hyperaldosteronism. "These drugs act on the mineralocorticoid receptor in the kidneys to lower blood pressure ...
MedPage Today - Sun, 09 Nov 2014 12:05

Severe Sleep Apnea Linked to Resistant Hypertension
Severe obstructive sleep apnea may interfere with blood pressure (BP)–lowering treatment in patients at high cardiovascular disease risk or with established cardiovascular disease, results of a multicenter clinical trial suggest. Doctors should ...
Medscape - Thu, 02 Oct 2014 13:56

Aldosteronism Screening for Hypertension Is Cost-effective
This study "is important and timely because of the recognized increased incidence of primary hyperaldosteronism as a cause for difficult-to-manage hypertension," said Douglas L. Fraker, MD, chief of the division of endocrine and oncologic surgery at ...
Medscape - Thu, 08 May 2014 09:46

Blood-Pressure Control Continues 3 Years' Postadrenalectomy
BOSTON — Blood-pressure control with or without medications was maintained for an average of 3 years in most patients who underwent adrenalectomy for primary hyperaldosteronism (PA) at 2 US endocrine surgery centers. These are the first long-term ...
Medscape - Mon, 05 May 2014 08:11

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Last update: September 2014