Some Angiotensin Receptor Blockers More Potent Than Others
Different angiotensin receptor blockers have distinct potencies for suppressing adrenal β-arrestin1-dependent post-myocardial infarction hyperaldosteronism, according to a letter published in the Dec. 30 issue of the Journal of the American College of ...
Doctors Lounge - Mon, 09 Feb 2015 09:37

Electrolytes in cardiology
Hypokalaemia can also be due to increased loss of potassium through renal excretion, which may be caused by diabetes insipidus, hypercalcaemia, hyperaldosteronism, excessive fluid replacement therapy and diarrhoea. A typical ECG for a patient with ...
The Pharmaceutical Journal - Tue, 03 Feb 2015 09:43

Expert examines contribution of aldosterone in obesity-related hypertension
Majewski also stressed that obesity-related hyperaldosteronism is different than true primary hyperaldosteronism. Guidelines from The Endocrine Society recommend that screening for primary hyperaldosteronism occur in patients with hypertension and ...
Healio - Fri, 24 Oct 2014 13:09

Public Release: 2-Feb-2015 NSU researcher discovers certain ARB drugs are ...
25, 2014) in an article titled "Different Potencies of Angiotensin Receptor Blockers at Suppressing Adrenal β-Arrestin1-Dependent Post-Myocardial Infarction Hyperaldosteronism." Results of the study are also published in Scientific Reports (Vol. 5, Jan.
EurekAlert (press release) - Mon, 02 Feb 2015 13:22

Aldosterone-Renin Ratio in the Assessment of Primary Aldosteronism
A middle-aged patient with diabetes and hypertension presented to his primary care physician for regular health assessment. His blood pressure was 183/116 mm Hg despite taking lisinopril (40 mg/d) and verapamil (180 mg/d). He had previously taken ...
JAMA_ The Journal of the American Medical Association - Tue, 08 Jul 2014 13:09

GSK announces 14 winners of Discovery Fast Track Challenge
Morris Brown, University of Cambridge (UK): Primary hyperaldosteronism; Dr. Federica Briani, Università degli Studi di Milano (Italy): Targeting bacterial infections; Dr. Christos Chatziantoniou, National Institute of Health and Medical Research ...
MedCity News - Mon, 01 Dec 2014 03:48

GSK names drug hunter challenge winners
PMLiVE - Tue, 02 Dec 2014 03:35

Winners of GSK Discovery Fast Track Challenge Announced
Genetic Engineering & Biotechnology News - Mon, 01 Dec 2014 11:07

Cambridge dominates GSK medical discovery challenge
Business Weekly - Wed, 03 Dec 2014 01:45

Estrogen May Protect Heart by Inhibiting Mineralocorticoid
Several anti-mineralocorticoid diuretics have been approved and are used to treat chronic heart failure, hypertension and a condition known as hyperaldosteronism. "These drugs act on the mineralocorticoid receptor in the kidneys to lower blood pressure ...
MedPage Today - Sun, 09 Nov 2014 12:05

Mild adrenal steroidogenic defects common in patients with high BP
“Is ACTH the driving stimulus regarding primary hyperaldosteronism? Is it possible to establish a continuum between hyperplasia and adenoma in primary hyperaldosteronism? Is stress-related high BP associated with ACTH-dependent aldosterone secretion ...
Healio - Fri, 26 Dec 2014 13:20

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Last update: September 2014