Auction will help 2 families coping with illness
The other recipient of the auction proceeds is Amber Gibbs, a mother of three small children who has a rare hereditary disorder, von Hippel-Lindau disease. VHL leads to abnormal growth of tumors. Two of her children have also been diagnosed with the ...
Richmond - Fri, 26 Jun 2015 12:41

High-resolution profiling of histone h3 lysine 36 trimethylation in metastatic ...
Despite recent advances in systemic therapy, median survival drops to ~2 years after development of metastatic disease. The von Hippel–Lindau (VHL) tumor-suppressor protein is inactivated in about 90% of ccRCC cases. Loss of VHL function occurs early ... - Mon, 15 Jun 2015 03:02

Kremmling sportsman club hosts benefit archery tourney for local family
Shannon, the mother of the family, has a genetic disease known as Von Hippel-Lindau disease, or VHL, a deficiency in bodily proteins that prevents tumors. The nodule needs to be removed, as it might be cancerous. “It's an on-going battle with her VHL ...
Summit Daily News - Fri, 26 Jun 2015 12:07

McClellan: Surgery renders former teacher a quadriplegic
Tara was 5 years old when her mother died from kidney cancer. That same type of cancer claimed one of Tara's aunts and her grandmother. Another aunt died of brain cancer. They all suffered from Von Hippel-Lindau syndrome, which is characterized by the ... - Tue, 02 Jun 2015 21:53

La Jolla Institute researchers identify molecular pathway that maintains Treg ...
Regulatory T cells (Treg cells) are part of the system of checks and balances that prevents the immune response from going overboard and causing autoimmune disease. Although critically important for shaping the immune ... Hypoxia-inducible factor 1α ... - Wed, 17 Jun 2015 04:04

Keeping a Lid on Inflammation
Newswise (press release) - Tue, 16 Jun 2015 17:33

Top 10 căn bệnh hiếm gặp, đáng sợ nhất hành tinh
Bệnh von Hippel - Lindau (VHL) hay còn được gọi là hội chứng von Hippel - Lindau (von Hippel - Lindau syndrome) là một loại bệnh có tính chất di truyền theo nhiễm sắc thể trội. Bệnh ảnh hưởng đến nhiều cơ quan của cơ thể như não, tụy, gan, thận, mắt...
Người Đưa Tin - Tue, 30 Jun 2015 16:35

Von Hippel-Lindau Disease - A Case Report and Review of Literature
The familial form of the common clear-cell variant of RCC is von Hippel-Lindau disease. Major manifestations include the development of RCC, pheochromocytoma, retinal angiomas, and hemangioblastomas of the brain stem, cerebellum, or spinal cord [1].
UroToday - Thu, 14 Feb 2013 03:48

Postsurgical adjuvant or metastatic renal cell carcinoma therapy models reveal ...
Renal cell carcinoma (RCC), normally considered an intrinsically chemotherapy-resistant cancer, is currently treated with targeted biologic therapies, including antiangiogenic tyrosine kinase inhibitors (TKIs), such as pazopanib. The efficacy of these ...
Science Magazine - Wed, 08 Apr 2015 11:11

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Last update: September 2014