From arterial hypertension complications to von Hippel-Lindau syndrome diagnosis
Von Hippel-Lindau syndrome is a rare, genetically based, autosomal dominant disorder. Its course is accompanied by the development of multiple neoplasms with the following tumours diagnosed most commonly in the central nervous system ...
7thSpace Interactive (press release) - Wed, 12 Aug 2015 17:11

Blindness can't stop entrepreneur
Von Hippel-Lindau syndrome (VHL) is a hereditary condition associated with blood vessel tumors of the brain, spinal cord and eye, according to People with VHL also have an increased risk of developing clear cell renal cell carcinoma, which ...
Dailyleader - Fri, 28 Aug 2015 08:45

The alluring idea that we can cure cancer has become a trap
"You win the Nobel Prize, you get to be director of the Cancer Institute, not by taking care of patients and discovering how to cure cancer but by cloning genes and discovering how Von Hippel-Lindau's disease is organized, and discovering how an ...
Washington Post (blog) - Thu, 06 Aug 2015 10:03

FDA Grants Breakthrough Therapy Designation to Exelixis' Cabozantinib for the ...
Cabozantinib received Breakthrough Therapy Designation based on the results of METEOR, the phase 3 pivotal trial comparing cabozantinib to everolimus in patients with RCC who experienced disease progression following treatment with a VEGF receptor ...
Yahoo Finance UK - Mon, 24 Aug 2015 05:33

Exelixis' cabozantinib gets US FDA breakthrough therapy designation to treat ... - Wed, 26 Aug 2015 04:37

The Big Hoot: First family to complete the Owl trail
Both were born with the gene that can cause VHL (Von Hippel-Lindau syndrome, a hereditary condition associated with Hemangioblastomas, which are blood vessel tumours of the brain, spinal cord, and eye). This a prime example of how The Big Hoot ...
Birmingham Mail - Tue, 11 Aug 2015 07:16

Renal Cell Carcinoma Histologies
The clear cell histology is generally characterized as an angiogenic tumor with Von Hippel-Lindau mutations. ... The non-clear cell histology represents approximately 20% of individuals with the disease and effective therapies are needed, notes McDermott.
OncLive - Mon, 17 Aug 2015 08:56

Von Hippel-Lindau Disease - A Case Report and Review of Literature
The familial form of the common clear-cell variant of RCC is von Hippel-Lindau disease. Major manifestations include the development of RCC, pheochromocytoma, retinal angiomas, and hemangioblastomas of the brain stem, cerebellum, or spinal cord [1].
UroToday - Thu, 14 Feb 2013 03:48

Grey's Anatomy features patient with von Hippel-Lindau disease
The second episode in a three-part series on Grey's Anatomy features a patient with von Hippel-Lindau disease (VHL). The next new episode in the show is expected to air on January 6. The first episode, "Adrift and at Peace," aired Dec. - Tue, 14 Dec 2010 20:53

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