Heat is on for desert explorers
Although his condition had baffled doctors, staff at Southampton General identified it as the rare immune system defect called Chronic Granulomatous Disease, and he is now making a recovery. Jonathan, 38, from Basingstoke, said: “My family has been ...
Daily Echo - Thu, 30 Oct 2014 04:43

Anti-TNF Treatment: Cancer and Infections
A link between malignancy and chronic inflammation, such as is seen in uncontrolled RA, is well recognized. "We assumed that patients taking biologics had more severe disease and ... "Use of the monoclonal antibodies infliximab or adalimumab, when ...
MedPage Today - Wed, 29 Oct 2014 08:11

Travel-Imported Mycobacterium Linked to Rare Skin Disease
When the treatment was unsuccessful and the toe lesion worsened, the patient was referred to the Veterans Affairs Medical Center in St. Louis, where pathologic evaluation of biopsy specimens showed extensive necrosis without granulomas and numerous AFB ...
Medscape - Tue, 28 Oct 2014 11:28

Araim Pharmaceuticals Given FDA Fast Track Designation to ARA 290 for the ...
Sarcoidosis, an orphan disease, is diagnosed by the presence of granulomas, typically in the lung, in adults between 20 and 40. Most patients resolve spontaneously or with available treatment options, but 30 percent go on to develop a chronic condition ...
PR Newswire (press release) - Tue, 28 Oct 2014 06:07

Teen Saved by Transplant, Killed by Superbug at NIH Hospital
Troy was born with chronic granulomatous disease or CGD, an inherited immunodeficiency, which made him more vulnerable to infections. At 5 months old, the boy had bladder surgery, but the incision kept opening up. Genetic tests revealed Troy had CGD.
NBCNews.com - Tue, 14 Oct 2014 09:49

Is your pet on pins and needles?
Lexie Hanna is a veterinarian and acupuncturist in Wilmington, Delaware, says pets can get relief from conditions like arthritis, chronic pain from disc disease, seizure disorders, lick granulomas, nerve injuries and dry eye. It also is sometimes ...
ConsumerAffairs - Wed, 22 Oct 2014 09:52

Test could confirm sepsis within an hour
Nursing home residents might benefit from a new way of diagnosing and treating sepsis made possible by a recent discovery out of the University of British Columbia. The test, which would look for a gene signature identified by the UBC researchers ...
McKnight's Long Term Care News - Fri, 24 Oct 2014 03:37

Time to cast a larger net
Neutrophils from patients with chronic granulomatous disease, who have mutations in the gene encoding phagocyte oxidase, are unable to produce ROS and fail to release NETs. However, when the investigators examine ROS production, they find that ...
Nature.com - Mon, 20 Oct 2014 06:57

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Last update: September 2014