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Pharmacyclics Reports Second Quarter 2014 Results
On July 28, 2014, the U.S. FDA granted IMBRUVICA full approval for the treatment of CLL patients who have received at least one prior therapy, and for the treatment of CLL patients with deletion of the short arm of chromosome 17 (del 17p CLL ...
Wall Street Journal - Thu, 31 Jul 2014 13:03



FDA expands approved use of Imbruvica for chronic lymphocytic leukemia
The U.S. Food and Drug Administration today expanded the approved use of Imbruvica (ibrutinib) to treat patients with chronic lymphocytic leukemia (CLL) who carry a deletion in chromosome 17 (17p deletion), which is associated with poor responses to ...
FDA.gov - Mon, 28 Jul 2014 09:07

Ibrutinib in CLL: Indication Expanded, Benefit Confirmed
Medscape - Mon, 28 Jul 2014 11:00

FDA Expands Approval of Rx for Rare Blood and Bone Disease
dailyRx - Mon, 28 Jul 2014 14:11

FDA OKs Imbruvica in Tough-to-Treat Form of CLL
MedPage Today - Mon, 28 Jul 2014 13:15

Imbruvica Approved for Expanded Use and New Labeling
Pharmacy Times - Wed, 30 Jul 2014 05:45

US FDA grants full approval for Imbruvica for two indications
pharmabiz.com - Wed, 30 Jul 2014 03:30

FDA gives full approval to ibrutinib for CLL
The Oncology Report - Mon, 28 Jul 2014 14:45



22Q11 awareness is on the right track now
For parents of children with 22Q11 Deletion Syndrome – which is the second most common chromosome disorder after Downs Syndrome – this is daily life. Now, thanks to the efforts of Biggleswade train driver Mark Tripp, whose eight year old son Adam has ...
Biggleswade Today - Thu, 31 Jul 2014 03:52

Beeton girl's playground wish comes true
Shannon was born with a rare chromosome deletion and suffers from seizures, kidney issues, severe scoliosis, growth and motor function issues, and also has moderate autism, according to her mom Michelle. “Unfortunately she has a host of medical issues, ...
Simcoe.com - Wed, 30 Jul 2014 07:03

Pharmacyclics: U.S. FDA Grants Regular Approval for Imbruvica
In CLL/SLL, the genetic mutation del 17p occurs when part of chromosome 17 has been lost or deleted. CLL/SLL patients with del 17p have poor treatment outcomes. Del 17p is reported in approximately 7 percent of treatment-naive CLL/SLL cases, and ...
Insurance News Net - Wed, 30 Jul 2014 22:37

Families from across the globe meet in Montpelier
MONTPELIER, Vt. - Karen Zecchinelli's son has a rare genetic disorder called "9P Minus." She says only a few hundred people in the world are living with the disorder, so she's invited families from across the globe to Montpelier for a get together.
WCAX - Sat, 26 Jul 2014 17:00

Genomic aberrations of the CACNA2D1 gene in three patients with epilepsy and ...
(79,314,673_79,337,679)_(86,790,392_86,817,601)del dn (ISCN: arr[hg19] 7q21.11q21.12(79,337,679-86,790,392)x1 dn) on chromosome band 7q21.11q21.12 harboring 14 genes (Figure 2) and a maternally inherited 150 kb deletion on chromosome band ...
Nature.com - Wed, 30 Jul 2014 03:18

Bowling benefit set for Baby Violet
Baby Violet, 2, was born with a rare chromosome deletion — so rare that only 13 other children in the world are known to have it. To help her parents pay for medical expenses, a bowling benefit has been scheduled for July 26 at Diamond Lanes in Beloit.
Beloit Daily News - Thu, 24 Jul 2014 14:02


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