A condition characterized by persistent spasms (
spasm) involving multiple
muscles, primarily in the lower limbs and trunk. The illness tends to occur in the fourth to sixth decade of
life, presenting with intermittent spasms that become continuous. Minor sensory stimuli, such as
noise and
light touch, precipitate severe spasms. Spasms do not occur during
sleep and only rarely involve cranial
muscles.
respiration may become impaired in advanced cases. (Adams et al., Principles of
neurology, 6th ed, p1492;
neurology 1998 Jul;51(1):85-93)
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