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Rheumatoid Nodule


Subcutaneous nodules seen in 20-30% of rheumatoid arthritis patients. They may arise anywhere on the body, but are most frequently found over the bony prominences. The nodules are characterized histologically by dense areas of fibrinoid necrosis with basophilic streaks and granules, surrounded by a palisade of cells, mainly fibroblasts and histiocytes.

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Rheumatoid noduleRheumatoid nodulosisNodulosis–arthropathy–osteolysis syndromeHeberden's nodeProgressive nodular histiocytosisCutaneous myelofibrosisSynovial membraneMilker's noduleNodule (medicine)PRG4

More information


  • Reported cases - Summary of cases reported on this disease.
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  • SearchMedica - Professional Medical Search.
  • WHO - World Health Organization.
  • PubMed - A service of the National Library of Medicine and National Institutes of Health.
  • MEDLINE - Literature from the National Library of Medicine.
  • MeSH - Medical Subject Headings.
  • DeCS - Health Sciences Descriptors.

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Last update: April 2009
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