Subcutaneous nodules seen in 20-30% of rheumatoid arthritis patients. They may arise anywhere on the body, but are most frequently found over the bony prominences. The nodules are characterized histologically by dense areas of fibrinoid necrosis with basophilic streaks and granules, surrounded by a palisade of cells, mainly fibroblasts and histiocytes.
Diagnosis and therapies
Rheumatoid nodule, Rheumatoid nodulosis, Nodulosis–arthropathy–osteolysis syndrome, Heberden's node, Progressive nodular histiocytosis, Cutaneous myelofibrosis, Synovial membrane, Milker's nodule, Nodule (medicine), PRG4
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