Ryanodine Receptor Calcium Release Channel; Calcium-Ryanodine Receptor Complex; Ryanodine Receptors; RyR1; Ryanodine Receptor 1; Ryanodine Receptor 2; Ryanodine Receptor 3

A tetrameric calcium release channel in the SARCOPLASMIC RETICULUM membrane of SMOOTH muscle cells, acting oppositely to sarcoplasmic reticulum calcium-transporting atpases. It is important in skeletal and cardiac excitation-contraction coupling and studied by using ryanodine. Abnormalities are implicated in CARDIAC ARRHYTHMIAS and muscular diseases.

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Ryanodine Receptor Calcium Release Channel (Calcium-Ryanodine Receptor Complex; Ryanodine Receptors; RyR1; Ryanodine Receptor 1; Ryanodine Receptor 2; Ryanodine Receptor 3)