Ribonucleoprotein, u5 small nuclear (Small Nuclear Ribonucleoproteins, U5; U5 snRNP; U5 Small Nuclear Ribonucleoproteins)
A nuclear rna-protein complex that plays a role in rna processing. In the nucleoplasm, the U5 snRNP along with U4-U6 snRNP preassemble into a single 25S particle that binds to the U1 and U2 snRNPs and the substrate to form spliceosomes.