(agents antihelminthiques; anthelminthiques; anti-helminthiques; medicaments antihelminthiques; vermifuges)

Agents destructive to parasitic worms. They are used therapeutically in the treatment of HELMINTHIASIS in man and animal.


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Les <b>Antihelminthiques</b>
Les Antihelminthiques


b) Les <b>antihelminthiques</b>
b) Les antihelminthiques





Diagnostic et thérapies



Rapide   Hiérarchique


  • Antihelminthiques: Agents destructive to parasitic worms. They are used therapeutically in the treatment of HELMINTHIASIS in man and animal.
  • Mebendazole: A benzimidazole that acts by interfering with CARBOHYDRATE METABOLISM and inhibiting polymerization of MICROTUBULES.
  • Albendazole: A benzimidazole broad-spectrum anthelmintic structurally related to MEBENDAZOLE that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)
  • Antihelminthiques Antinématodes: Substances used in the treatment or control of nematode infestations. They are used also in veterinary practice.
  • Humains: Membres de l'espèce Homo sapiens.
  • Animaux: Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain Eukarya.
  • Résidus Médicament: Drugs and their metabolites which are found in the edible tissues and milk of animals after their medication with specific drugs. This term can also apply to drugs found in adipose tissue of humans after drug treatment.
  • Trichuris: A genus of nematode worms comprising the whipworms.
  • Ivermectine: A mixture of mostly avermectin H2B1a (RN 71827-03-7) with some avermectin H2B1b (RN 70209-81-3), which are macrolides from STREPTOMYCES avermitilis. It binds glutamate-gated chloride channel to cause increased permeability and hyperpolarization of nerve and muscle cells. It also interacts with other CHLORIDE CHANNELS. It is a broad spectrum antiparasitic that is active against microfilariae of ONCHOCERCA VOLVULUS but not the adult form.
  • Praziquantel: An anthelmintic used in most schistosome and many cestode infestations.
  • Antiparasitaires: Drugs used to treat or prevent parasitic infections.
  • Ascaris Lombricoïdes: A species of parasitic nematode that is the largest found in the human intestine. Its distribution is worldwide, but it is more prevalent in areas of poor sanitation. Human infection with A. lumbricoides is acquired by swallowing fully embryonated eggs from contaminated soil.
  • Test De Sensibilité Parasitaire: Tests that demonstrate the relative effectiveness of chemotherapeutic agents against specific parasites.
  • Nematoda: A class of unsegmented helminths with fundamental bilateral symmetry and secondary triradiate symmetry of the oral and esophageal structures. Many species are parasites.
  • Ancylostomatoidea: A superfamily of nematode parasitic hookworms consisting of four genera: ANCYLOSTOMA, NECATOR, Bunostomum, and Uncinaria. ANCYLOSTOMA and NECATOR occur in humans and other mammals. Bunostomum is common in ruminants and Uncinaria in wolves, foxes, and dogs.
  • Numération Oeuf Parasite
  • Tiabendazole: 2-Substituted benzimidazole first introduced in 1962. It is active against a variety of nematodes and is the drug of choice for strongyloidiasis. It has CNS side effects and hepatototoxic potential. (From Smith and Reynard, Textbook of Pharmacology, 1992, p919)
  • Résistance Aux Médicaments: Diminished or failed response of an organism, disease or tissue to the intended effectiveness of a chemical or drug. It should be differentiated from DRUG TOLERANCE which is the progressive diminution of the susceptibility of a human or animal to the effects of a drug, as a result of continued administration.
  • Pyrvinium, Composés
  • Strongyloïdes Stercoralis: A species of parasitic nematode widely distributed in tropical and subtropical countries. The females and their larvae inhabit the mucosa of the intestinal tract, where they cause ulceration and diarrhea.
  • Ovis: Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS.
  • Female
  • Lévamisole: An antihelminthic drug that has been tried experimentally in rheumatic disorders where it apparently restores the immune response by increasing macrophage chemotaxis and T-lymphocyte function. Paradoxically, this immune enhancement appears to be beneficial in rheumatoid arthritis where dermatitis, leukopenia, and thrombocytopenia, and nausea and vomiting have been reported as side effects. (From Smith and Reynard, Textbook of Pharmacology, 1991, p435-6)
  • Livestock
  • Médecine Africaine Traditionnelle: A system of traditional medicine which is based on the beliefs and practices of the African peoples. It includes treatment by medicinal plants and other materia medica as well as by the ministrations of diviners, medicine men, witch doctors, and sorcerers.
  • Male
  • Angiospermes: Any member of the more than 250,000 species of flowering plants. Angiosperms are often differentiated from GYMNOSPERMS by their production of seeds within a closed chamber (OVARY, PLANT). The Angiosperms division is composed of two classes, the monocotyledons (Liliopsida) and dicotyledons (Magnoliopsida).
  • Enfant: Personne âgée de 6 à 12 ans. Une personne âgée de 2 à 5 ans est un enfant d'âge préscolaire.
  • Plantes Médicinales: Plants whose roots, leaves, seeds, bark, or other constituent possess therapeutic, tonic, purgative, or other pharmacologic activity when administered to higher animals.
  • Ethnobotanique: Science des plantes et des coutumes agricoles d'un peuple. Dans le domaine de la médecine, l'emphase est mise sur la médecine traditionnelle, et l'existence et l'utilisation de plantes médicinales et de leurs constituants, historiquement et à l'époque actuelle.
  • Feuilles Plante: Structures étendues, d
  • Chiens: The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
  • Tanzania
  • Phytothérapie: Utilisation de plantes ou d'herbes pour soigner des maladies ou pour atténuer la douleur.
  • Depsipeptides: Compounds consisting of chains of AMINO ACIDS alternating with CARBOXYLIC ACIDS via ester and amide linkages. They are commonly cyclized.
  • Extraits Plantes: Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard.
  • Fer: A metallic element found in certain minerals, in nearly all soils, and in mineral waters. It has the atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems. Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms. Depletion of iron stores may result in iron-deficiency anemia. Iron is used to build up the blood in anemia. (From Dorland, 27th ed)
  • Médecine Africaine Traditionnelle: A system of traditional medicine which is based on the beliefs and practices of the African peoples. It includes treatment by medicinal plants and other materia medica as well as by the ministrations of diviners, medicine men, witch doctors, and sorcerers.
  • Adolescent: Personne âgée de 13 à 18 ans.
  • Adulte: A person having attained full growth or maturity. Adults are of 19 through 44 years of age.
  • Benzimidazolés: Compounds with a BENZENE fused to IMIDAZOLES.
  • Enfant D': Enfant âgée de 2 à 5 ans.
  • Prevalence
  • Méthode Double Insu: Méthode utilisée pour étudier une drogue ou un procédé au sujet desquels les participants et les investigateurs ignorent qui reçoit réellement le traitement spécifique.
  • Nourrisson: Enfant âgé de 1 à 23 mois.

Plus d'information

  • CISMeF - Catalogue et Index des Sites Médicaux Francophones.
  • OMS - Organisation Mondiale de la Santé.

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Dernière mise à jour: Avril 2009