A tumor necrosis factor receptor subtype found in a variety of tissues and on activated lymphocytes. It has specificity for FAS LIGAND and plays a role in regulation of peripheral immune responses and apoptosis. Multiple isoforms of the protein exist due to multiple alternative splicing. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the cytoplasm.


Symptoms and diagnosis

Symptoms:

    


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