A hemostatic disorder characterized by a poor anticoagulant response to activated protein c (APC). The activated form of Factor V (factor va) is more slowly degraded by activated protein c. Factor V Leiden mutation (R506Q) is the most common cause of APC resistance.


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File:<b>Protein C</b> anticoagulant.

File:Protein C anticoagulant.
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<b>APC Resistance</b>

APC Resistance
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<b>Activation</b> of <b>protein C</b> by

Activation of protein C by
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of the <b>APC resistance</b> test

of the APC resistance test
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of the <b>protein C</b> system.

of the protein C system.
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<b>Resistance</b> to <b>activated</b>

Resistance to activated
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<b>APC</b>-catalyzed inactivation of

APC-catalyzed inactivation of
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<b>protein C</b> (<b>APC</b>) <b>resistance</b>

protein C (APC) resistance
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Last update: September 2014