what are the odds of a child in the year 2008 in America being born with Transposition of the Great Vessels?

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I have a son with this and was just wondering how many children were born with this anomoly in 2008 in the US.
  (+ info)

Transposition of the great vessels- who is the musard procedure named after?

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Dr. Michael Gatzoulis of the Royal Brompton Hospital, London, England, working with Dr. Liu, examined 51 patients who 25 years ago had received the Mustard procedure in Toronto. They found that nearly a quarter of the sample were beginning to develop heart rhythm problems which, left untreated could lead to heart failure.

The Mustard procedure – developed by Dr. William Mustard with support from the Heart and Stroke Foundation of Canada– was the first operation to correct the congenital abnormality that produced “blue babies.

Blue babies are born with a defect called transposition of the great vessels, in which blood from the lungs flows back to the lungs and blood from the body flows back to the body. The two major arteries coming out of the heart, the aorta and the pulmonary artery are connected to the wrong chambers. Such babies look blue because insufficient oxygen is circulating in their bodies.

The Mustard procedure restores the circulation but reverses the direction of the blood flow in the heart. In a normal heart, de-oxygenated, blue, blood is pumped into the lungs via the right ventricle. Then it is distributed throughout the body via the left ventricle. In the Mustard procedure, blood is pumped to the lungs via the left ventricle and disseminated throughout the body via the right ventricle.  (+ info)

What is the chance of a child being born with Transposition of the great Arteries? a heart defect?

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I have a son who was born with a congenital heart defect, Transposition of the Great Arteries (or Vessels). Heart defects are the number 1 defects for live births, occurring in 1 out of every 100 births. Now, what are the odds for a child to be born with Transposition (i.e. 1 in ___ births), as it is pretty common?
Actually congenital heart defects occur in 1 of every
125-150 children, so they are quite common.
Of all heart defects, 5% will be transposition of
the great arteries, occurring overall at a rate of
2-3 per 10,000 births. Transposition is more
common in boys than girls.  (+ info)

Clinically how to differentiate between anomalous pulmonary venous return & transposition of great vessels?

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On seeing snowman or figure-of-eight heart sign of chest X-ray, clinically how to differentiate between anomalous pulmonary venous return & transposition of great vessels as the underlying disease? (by location of murmur maybe??)
Thanks ganga. Clinically if I give you a snowman CXR, how would you tell me from history and/or physical examination what the most likely cause is (tetralogy of fallot, vs anomalous pulmonary venous return, vs transposition of great vessels)?
Total anomalous pulmonary venous connection (TAPVC), also known as total anomalous pulmonary venous drainage (TAPVD) and total anomalous pulmonary venous return (TAPVR), is a rare cyanotic congenital heart defect (CHD) in which all four pulmonary veins are malpositioned and make anomalous connections to the systemic venous circulation.(Normally, pulmonary venous return carries oxygenated blood to the left atrium and to the rest of the body). A patent foramen ovale or an atrial septal defect must be present, or else the condition is fatal due to a lack of systemic blood flow.
A Partial anomalous pulmonary venous connection is a congenital defect where right atrium is the point of return for the blood from some (but not all) of the pulmonary veins.
It is less severe than total anomalous pulmonary venous connection.
It can be diagnosed with angiography or echocardiography.
Total anomalous pulmonary venous return (TAPVR) correction

* TAPVR occurs when the pulmonary veins bring oxygen-rich blood from the lungs back to the right side of the heart, instead of to the left side of the heart, where it should be.
* This condition requires surgery to correct it. When the surgery is done will depend on how sick the baby is. The surgery may be done in the newborn period if the infant has severe symptoms. If it is not done right after birth, it is done in the first 6 months of the baby’s life.
* TAPVR repair requires an open-heart surgery. The pulmonary veins are attached to the left side of the heart, where they belong, and any abnormal connections are closed.
* If a PDA is present, it is tied off and divided.


Transposition of the great vessels (TGV) is a group of congenital heart defects (CHDs) involving an abnormal spatial arrangement of any of the primary blood vessels: superior and/or inferior vena cavae (SVC, IVC), pulmonary artery, pulmonary veins, and aorta. CHDs involving only the primary arteries (pulmonary artery and aorta) belong to a sub-group called transposition of the great arteries (TGA).
Transposition of the great vessels repair
* In a normal heart, the aorta comes from the left side of the heart, and the pulmonary artery comes from the right side. Transposition of the great vessels is when these arteries come from the opposite sides of the heart.
* Correcting transposition of the great vessels requires open-heart surgery. If possible, this surgery is done shortly after birth.
* The most common repair is an arterial switch. The aorta and pulmonary artery are divided. The pulmonary artery is connected to the right ventricle, where it belongs. Then, the aorta and coronary arteries are connected to the left ventricle, where they belong.  (+ info)

I have some concerns about transposition of the Great Arteries?

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I am almost 5 months pregnant and i just found out that my baby girl might have a heart defect. The doctor calls it transposition of the Great Arteries. I just want to know if surgery would be able to fix her heart and what the chances are of her recovering well from it. This will be my first child. I am very concerned. I also want to know if she would be able to have a normal life or if she would have to live with health problems throughout her whole life.
http://emedicine.medscape.com/article/900574-overview pls visit  (+ info)

Does anyone here have Transposition of the Great Arteries?

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Just looking for people with the same Heart Condition
I have. If so did you have the Mustard Procedure done?
lls1757 - If you had a Mustard procedure, then you most likely have what we call d-transposition of the great arteries. It is actually the most common heart defect causing babies being blue in the newborn period, so there are plenty of you out there! The Mustard is one of the "atrial switch" procedures first pioneered by Dr. Senning in 1959. However, because the Senning procedure was so difficult, the Mustard procedure (developed by Dr. Mustard in Toronto in 1963) quickly became the preferred atrial switch procedure. Nowadays, if possible, we prefer to perform an arterial switch (Jatene switch) because it allows the left ventricle to pump blood to the body as it would in a person with a normal heart.

The Mustard and Senning procedures saved a LOT of lives. However, we have learned that people who have had a Mustard/Senning do have things that we need to monitor for long term. Firstly, there is a tendency to develop heart rhythm problems that require a pacemaker. Also, since the right ventricle, which is designed to pump blood to the lungs, now pumps blood to the body in a person with a Mustard/Senning, it can start to wear out over decades leading to heart failure. In addition, the tricuspid valve which, in a transposed patient, is on the left side instead of the right, has a tendency to become leaky. I'm glad that you have done well, but for these reasons it is VERY IMPORTANT that you have regular follow-up with a cardiologist familiar with congenital heart lesions!

This is a growing field, and the most experienced centers for ACHD in the United States right now are at Harvard, the Mayo Clinic, and UCLA, but there are many other centers that have experts on adults with congenital heart disease. If you want to get in touch with others who are still alive today thanks to the procedure that Mustard developed, I suggest you visit the Adult Congenital Heart Association, the largest patient-run organization for adults with congenital heart diseases in the world. Their website is http://www.ACHAHeart.org and includes a message board where I guarantee there are plenty of people who know exactly what you live with! The oldest patients who had the Mustard are now into their 40s! Good luck to you! Hope that helps!  (+ info)

why do babies with transposition of great arteries have increased birth weight ?

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every one of my professors know that TGA babies are large at birth but no body knows why ... it is not even given in perloff ... anbody??
these babies are not edematous , they do not have water clogged in them , they are just well built and large ... but why ??
I wonder if it is fluids backing up because the heart can't handle the increased blood volume. Just a thought...do these baby patients have to take large amounts of diuretics?  (+ info)

What great blood vessels of the heart have semilunar valves?

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Describe a typical semilunar valve and tell how it works
Semilunar valves
These are located at the base of both the pulmonary trunk (pulmonary artery) and the aorta, the two arteries taking blood out of the ventricles. These valves permit blood to be forced into the arteries, but prevent backflow of blood from the arteries into the ventricles. [1] These valves do not have chordae tendineae, and are more similar to valves in veins than atrioventricular valves
http://biology.about.com/od/anatomy/a/aa062207a.htm  (+ info)

Left Transposition Of The Great Arteries?

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I was just wondering if there are others out there who have it as well, and would like to share some information about it.

I'm 21 years old, and have LTGA. I had open heart surgery at 3 years old (I'm not sure whether it was a Sennings operation, Arterial switch, or something else). During my teenage years I developed Arrhythmia in the upper chambers. I've had to undergo a cardiac catherization and am on heart medication.

Anybody else out there with the same problems, or at least know of a online group or something?
http://achaheart.org/

I was born with TGA, not sure what form of it, but they performed a Mustard procedure when I was 2, thru open heart surgery. I'm 21 now. Instead of switching the places of the valves, they created baffles (traffic tunnels for my blood), and I hadn't had any problems until about 4 months ago when I got a headache and it never went away.

I went in for a cardic cath in Oct. and I go back in open heart in Feb. Apparently there's a hole in a wall between my valves.

The http://achaheart.org/ is Adult Congenital Heart Association. There are tons of people on there with pretty much everything you can imagine in the way of heart conditions and procedures done. They helped me out a lot, I'm pretty sure you can find at least one person on the site that has exactly what you have.

Good luck!  (+ info)

Transposition of the great Arteries?

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My sister in Law is pregnant with twins, one of which has transposition of the great arteries. I have read about it, researched it, and I understand the condition what I am looking for is people who have it, doctors who treated it, Parents/ Family menbers of children with it. I want to know what comes after the sugery. We are going with the arterial switch procedure. Thank You all for information
Colleen - I'm sorry to hear that one of your sister's babies has transposition. As you probably know by now, transposition of the great arteries means that the baby's pulmonary artery and aorta are switched and, therefore, come off the wrong side of the heart. That means instead of the blood going from the body to the lungs and back again, there are two separate loops of blood, one of which keeps circulating through the lungs and one of which keeps circulating through the heart.

Since the 1950's, we have had the technology to operate on babies with this condition to restore the normal flow of blood. Initially, a pair of tunnels was created within the top chambers of the heart (the atria) to redirect the blood so that red blood returning from the lungs would go out to the body and blue blood returning from the body would go to the lungs for reoxygenation. The two methods of doing this are called the Mustard and Senning procedures. The problem is that over time, we have learned that as these patients grow up, they tend to have heart rhythm abnormalities, heart failure and problems with a leaky valve.

The arterial switch is the closest that we can come to restoring completely normal anatomy. Unfortunately, since it was first performed in the mid 1970s, the oldest patients who have gone through this procedure are only in their late 20s or early 30s. That means we don't yet have the experience to know how these patients do as they reach their 30s, 40s, 50s or beyond.

Assuming there are no additional heart defects, once these babies have recovered from the surgery, most have very normal childhoods and (except for the scars on their chests) don't look or act any differently from their peers. HOWEVER, they still need to be seen regularly by their heart doctors because there is still a risk of developing problems with obstruction of blood flow (in 10% of patients or more), heart rhythm abnormalities (in up to 10% of patients), leaky valves (in up to 5% of patients), heart failure (in up to 5% of patients), and other problems.

I would suggest asking the pediatric cardiologist if there are any families in your area who have gone through the same surgery and if any of them would be willing to talk to you. Hope that helps. All the best!  (+ info)

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