FAQ - Supranuclear Palsy, Progressive
(Powered by Yahoo! Answers)

Can anyone help with information on proper diagnosis and treatment for Progressive Supranuclear palsy?


mother recently diagnosed w/PSP - i have reason to suspect a hasty misdiagnosis and would like the best possible recommendations for proper course to follow.
----------

The diagnosis of PSP is based on the physical examination (the eye movement problems are quite characteristic, but are not always present early in the disease course) and on ruling out other, similar movement disorders such as Parkinson's disease, Creuzfeld-Jacob disease etc. If I had any concerns about the diagnosis of one of my relatives, I would definitely seek second opinion from a trusted neurologist who is specializing in movement disorders.

There is currently no effective treatment for PSP. Antiparkinsonian medications and antidepressant medications have been tried, with a little improvement in some patients. Supportive therapies can include walking aids, physical therapy, feeding tube placement.
There are some research trials going on, you can check the National Institutes of Health website (clinicaltrials.gov) for the latest.

Good luck to you and your mom. I added some links below.  (+ info)

Is progressive supranuclear palsy (PSP) a demyelinating disease?


I know the symptoms and the conditions of people with the disease, but I don't know if the degeneration has to do with the myelin of the nerves or if it is from some other factor.
----------

i cant be sure... its related to parkinsons and alzheimers so i think it might be but the damage is so specific that i think damage to the myelin would cause more widespread damage... but dont take my word for it.  (+ info)

can long term poisioning by a person cause supranuclear progressive palsy?


just wondering, i have a strong feeling that this persons disease could be caused by another
----------

  (+ info)

I need to know some natural medicines to help with PSP (Progressive Supranuclear Palsy)?


Is there any kind of treatment people have found useful? vitamins? minerals? even ancetodal answers would be appreciated. thanks
----------

PSP very similar to Parkinson's. While I do not know of any specific recommendations for PSP, I imagine that many of the same things which may help manage Parkinson's might also help with PSP. For more infomation on what I have that may help with Parkinson's, see:

http://www.tbyil.com/Parkinsons_Disease.htm

Note that while Parkinson's Disease has been linked to heavy metals and other toxins as has PSP, PSP has not been specifically linked to aluminum as has Parkinsons.

I would simply repeat the information on my website here, as I usually do, but in this instance it is much too lengthy to include in a single message here. Also, I will tell you in advance that, while I am not trying to sell you anything and while my website is intended primarily as an informational site, it does contain sales links and adverstising (the same as does this site). Anyone who objects to that is advised to simply not go there.

All the best!  (+ info)

A disease similar to progressive supranuclear palsy?


My grandfather died three years from a disease that was similar to progressive supranuclear palsy. He was a construction worker for close to 50 years and retired finally when we was about 69. (sorry for adding that I just have a very intense feeling of pride for him) His symptoms started about a year after his retirement and was first diagnosed as Alzheimer's. Then about a year after that they told us it was PSP, finally about a year before he died the neurologist told us it was a different disease because it only affected the one side of his body I believe was the reasoning behind the new diagnosis. The doctor told us that although it was similar to PSP it was a totally different disease none the less. I believe it also had to do with his nerves dying as well as parts of his brain. By the end he could barely move at all and was bedridden, his vocal skills were gone although he still was totally aware of his surrounding and the people he loved and knew, thank you for your time. ran out
Thank you for you time my grandmother woke up finally and told me it was cortical basal ganglionic degeneration, if anyone knows of a site that explains what it is in plain terms please let me know so far everything I have found are basically medical journals. Thanks again for your time.
Thank you for you time my grandmother woke up finally and told me it was cortical basal ganglionic degeneration, if anyone knows of a site that explains what it is in plain terms please let me know so far everything I have found are basically medical journals. Thanks again for your time.
----------

have you tried sites like mayo clinic or searching medical journals? google does good journal searches you might have better luck searching your Grandfathers symptoms that way especially since you cannot fully fit it in here. I wish I had more information for you. If you have 'health team' at your doctors office they some times have a phone nurse you could call them and ask though I am not sure how much neurology background your average family practice nurse might have. Best of luck finding answers.  (+ info)

Does anyone in this world know of any case of Progressive Supranuclear Palsy getting cured/ better?


Progressive Supranuclear Palsy (PSP) info
www.psp.org
Has any of the traditional or alternate therapy proved worthwile in PSP patients?
----------

Homeopathic Remedies prescribed according to the patients symptoms not of the disease will help treat and cure it. Homeopathy will not treat Progressive Supranuclear Palsy (PSP) it will treat and cure the person who is affected by it by treating the patients symptoms.
The symptoms of the patient and details about him not the name of the disease. Please post your details exactly the way you feel them from head to toes.
Take Care and God Bless you !  (+ info)

Treatment for PROGRESSIVE SUPRANUCLEAR PALSY ( PSP)?


I am from Kerala in India. My beloved father aged 81 years was diagnosed to be having PROGRESSIVE SUPRANUCLEAR PALSY (PSP) about one and half years back.This is a Parkinson Plus movement disorder in Pakinsonism (variant of Parkinson disease) group of diseases.His body balance is lost and cannot stand on his foot,his speech is not legible,he has swallowing difficulty which might result in choking or aspiration of food into lungs, his eye ball movement is restrained etc. etc....Allopathy says this is due to progressive degeneration of brain cells (nuerons) controlling movements in the body and there is practically no treatment for this disease. They have been giving him Syndopa Plus(100+25) 11/2 Tabs 3 times daily. Is there any treatment in any system of medicine? Please help!This is an appeal from a son to save his very very affectionate father.
----------

Sorry to hear your dad is ill, I guess this isn't really what you want to hear but this is what I came up with.

There is currently no effective treatment for PSP, although scientists are searching for better ways to manage the disease. In some patients the slowness, stiffness, and balance problems of PSP may respond to antiparkinsonian agents such as levodopa, or levodopa combined with anticholinergic agents, but the effect is usually temporary. The speech, vision, and swallowing difficulties usually do not respond to any drug treatment.. Another group of drugs that has been of some modest success in PSP are antidepressant medications. The most commonly used of these drugs are Prozac, Elavil, and Tofranil. The anti-PSP benefit of these drugs seems not to be related to their ability to relieve depression. Non-drug treatment for PSP can take many forms. Patients frequently use weighted walking aids because of their tendency to fall backward. Bifocals or special glasses called prisms are sometimes prescribed for PSP patients to remedy the difficulty of looking down. Formal physical therapy is of no proven benefit in PSP, but certain exercises can be done to keep the joints limber. A surgical procedure, a gastrostomy, may be necessary when there are swallowing disturbances. This surgery involves the placement of a tube through the skin of the abdomen into the stomach (intestine) for feeding purposes.

Good wishes to you and your family  (+ info)

Anyone had a patient with Progressive Supranuclear Palsy?


If so what guided your DDX?
----------

at this level of suspiscion you should be in contact with a neurologist to ensure correct diagnosis, good luck  (+ info)

Progressive Supranuclear Palsy?


Does anyone know how this disease is transmitted/concieved? Is it genetic, or does someone have to be exposed to a substance of some sort (chemicals/radiation/etc)?

Can it be passed down to family members?
----------

PSP is a rare degenerative neurological disorder. The cause is unknown. It is unknown whether PSP is caused by hereditary factors, environmental factors, or a combination of both.. It is not "transmitted or conceived"...it just happens. It is often misdiagnosed as Parkinson's disease.  (+ info)

Progressive Supranuclear Palsy (PSP) advice?


Can it be brought on rapidly due to an operation ? My father was diagnosed three years ago with Parkinson's Plus (possibly MSA) but had a fall about 2 months ago, he broke his hip on the friday and was taken into hospital whereby he had a partial hip replacement the following day. Apart from the pain on the friday and saturday before the op he was ok. After the operation he was pretty much semi comatosed for a fortnight then slowly came around to being about 5% mentally of his former self. Starred fixed glaze eyes, hallucinations and problems moving his hands prompted him to be re-diagnosed as having PSP which I believe if this is the case he has little hope of recovery (to his former parkinsons self). Can anyone shed any light onto why the operation would accelerate the condition so rapidly and is there anything we can do for him.

Many thanks
----------

You asked a tough one and I don't know enough to provide the answer you deserve and I'm not sure who does.

I question the re-diagnosis although it could be correct. But because a major symptom of MSA is orthostatic hypotension, it is possible that the condition left him open to stroke. Although at first I thought he might have had a reaction to anesthesia, I know think it is possible that your father actually had some kind of stroke or TIA.
http://www.newswise.com/articles/view/545127/
http://findarticles.com/p/articles/mi_m0FSL/is_6_71/ai_64424153/

Although the risk is greater for a cardiac patient, there is a significant risk for someone with any form of hypotension.

Oddly enough sometimes beta blockers are prescribed after surgery. These would cause blood pressure to drop which could have increased his risk had this occurred. I doubt if it did because the doctors would have been aware of the MSA but it is a thought.

While it is true that the symptoms you describe can indeed by ascribed to PSP, there is certainly overlap with MSA, another parkinsonian-family disease. On the other hand it is quite possible that he was misdiagnosed from the onset.

An early symptom of PSP is difficulties with balance. Since that is also a major symptom of MSA there is a differential diagnosis issue. It also leads to falls in both conditions. And falls as you have already experienced can be life threatening.

The stare, however, while not always typical of early PSP where the visual symptoms are lack of focus, as the disease progresses the eyes dry and there is a lack of blinking.

One of the best descriptions of PSP is found at the National Institutes of Health. You would best know how to relate his prior condition to the descriptions found here:
http://www.ninds.nih.gov/disorders/psp/detail_psp.htm

Another possibility could be drug interaction but I have no idea what he was taking before the fall nor after.

You might be able to get more information from his medical-surgical team...maybe. Perhaps you should consult a different neurosurgeon who might think that you want to sue so probably won't talk to you but who knows. You are just looking for answers. This really isn't about fault - it is about understanding what happened and why and if anything can be done.

I also think there are better places than Y!A to ask this kind of question. You might try WeMove.org. Register so that you can join a discussion board. If you do that you will need more specific information. His symptoms before the fall, his medications. And after the fall: anesthesia, medications. What pain killer(s) is he being given?
http://www.wemove.org/psp/

There are also some online sites where you can ask a doctor a question. Please organize all of the information first. The problem is that this is big question so do not expect it to be answered but you may get some more clues.
http://www.doctorslounge.com/ask.htm
http://www.askthedoctor.com/index.php/topics-a-z.html

Some other questions which come to mind are does he have any other medical conditions? Does he have, for example, a prostate problem? Was he beginning to dehydrate before the fall? Sometimes it is difficult to tell but do your best to recall the signs of lower fluid intake which could have been going on for some time prior to the fall. Some of the symptoms you describe are also dehydration symptoms.

I am so sorry to hear about what happened. It must be heartbreaking for you and your family.  (+ info)

1  2  3  4  5  

Leave a message or picture about "Supranuclear Palsy, Progressive" or enter the forum: