can retinoblastoma be treated with the cancer drug gleevec?
Using gleevec for retinoblastoma would not be considered a standardized approach as there are other first and second line treatments available. Gleevec has only been proven beneficial/effective in chronic myelogenous leukemia (CML) and gastointestinal stromal tumors (GIST). In cllinical trials for other types of cancer gleevec has not been as effective as a single agent. What gleevec has done is open up the door of possibility for other tyrosine kinase inhibitor drugs to be developed that will target different cancer types (includes Sunitinib, Dasatinib, Erlotinib, Sorafenib, etc)
So the answer is . . probably not . . you might try researching clinical trial information about the drug, but retinoblastoma probably doesn't have the 'targets' needed in the tumor for the drug to be effective against it. (
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red eye or retinoblastoma or what?
in all of my babys pictures he has red eye in both eyes or sometimes just in one eye.sometimes its a really bright like laser beam red in both eyes. and occasionally just a darker red in one eye but not the other. is that normal? or could he have retinoblastoma or some other eye problem?
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Who are some celebrities that have, or had, retinoblastoma (eye cancer)?
Retinoblastoma is a childhood cancer that predominately affects children between infancy and five years old.
A few celebrities that have been touched by this disease include actress Hunter Tylo (The Bold and the Beautiful) whose young daughter (Katya) lost an eye to this cancer.
http://en.wikipedia.org/wiki/Hunter_Tylo
Actor, Matthew Ashford's (Days of our lives) young daughter, Emma, was diagnosed with the disease and she also lost an eye.
http://en.wikipedia.org/wiki/Matthew_Ashford
Derek Fisher, NBA player, has a young daughter (Tatum) with retinoblastoma.
http://www.theinsider.com/news/295444_Derek_Fisher_talkes_about_daughter_s_cancer
When Peter Falk (actor) was three years old he lost his eye to cancer.
http://en.wikipedia.org/wiki/Peter_Falk (
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my daughter was thought to have retinoblastoma she had mri now they do not know what she has anyone can help?
You need to see someone who knows what they are looking for, alot of doctors have never seen an rb, only in books. You need to see a pediatric opthamologist. If you let us know the area you are in, I'm sure with a quick search I could let you know the type of place you need.
I'm in Australia, and travel 100 miles to see our specialist.
We needed a referral from our GP, but fortunately when he saw our 2 y.o. son he recognised something wasn't right, and put us in touch with the right person.
Things to try, take a picture using a flash in a darkish room and see if you get "redeye" in both eyes. If one is white, it could be a sign of rb.
Put a book or something in between the 2 eyes to isolate each eyes vision and move something in front of each eye & see if she follows with each eye. With the tuma the vision will be so blurry she might not be able to identify the object to follow it.
Under fluro lights and some other lighting conditions, when you look at the black part of the eye, you will get the sensation that you can look right into the eye to the back of it, it seems really wierd.
I could go on, but that's enough for now. I hope she is all clear. (
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11. How is retinoblastoma usually detected? ?
Heidi,
Ninety percent of all retinoblastoma cases are diagnosed within the first three years of the child's life. On average, children with familial retinoblastoma typically are diagnosed at four months of age. When there is no family connection, the cancer is usually diagnosed when the child is approximately one to two years of age. There are two types of retinoblastoma. Familial retinoblastoma is hereditary, and is bilateral (affects both eyes). Familial retinoblastoma represents 10% of cases. It is associated with a long-term predisposition to other types of cancer. The second type of retinoblastoma, responsible for 70% of all new cases, is unilateral (only one eye is affected). It represents the non-heritable form of the disease, and carries no increased risk of a second tumour. Pediatricians can screen for vision and/or life threatening eye diseases. The minimal "well baby" screening for newborns is done during the first three months of life should include the following exams - The Red Reflex -checks for a normal red reflection in the eye that occurs when light travels inside the eye, hits the retina and the blood tissue, and is reflected back. The Corneal Light Reflex - when a light is shined into each cornea a symmetrical beam of light is reflected back in the same spot on each eye. This helps to determine whether the eyes are crossed. An Eye Examination - to check for any structural abnormalities. From six to twelve months of age, the eyes' ability to fix and follow objects both individually and together is evaluated. Between the ages of three and five, the examination of the eyes is coupled with testing for visual acuity, colour vision and depth perception. Parents also may want to look for eye abnormalities by directly examining each of the child's eyes under good lighting conditions. Both eyes should appear equal in size, be aligned, and should be able to move together and focus forward. Parents can observe the red reflex can be seen by dimming the room lights and using a flashlight to shine light directly into the child's eyes.
ALL ANSWERS SHOULD BE THOROUGHLY RESEARCHED, IN ANY FORUM AND ESPECIALLY IN THIS ONE. - MANY ANSWERS ARE FLAWED.
The information provided here should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions.
I add a link with details of this subject
http://www.answers.com/
topic/retinoblastoma-diagnosis
Hope this helps
matador 89
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My grandson is 9.He may have Coats disease or retinoblastoma,Is there any treatment for coat's?
He is her only child.He is a sweet child.and has beautiful blue eyes.His C.T. scan shows a 3mm calcified density indicative of infection,inflammation or neoplasm.Why is this happening to this sweet,loving child.He has hardly any vision in his left eye.
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The main symptom of Coats’ disease is the deterioration in either central or peripheral vision. Peripheral vision is sometimes called doughnut or side vision.
Coats’ disease causes retinal capillary dilation, malformation and leakage. Some subretinal bleeding may be experienced and there is a threat of retinal detachment. Although it is recorded that changes in the blood vessels accompany the later stages of the condition, this is not always seen and it is widely believed that the earliest changes in the small vessels of the retina tend to increase in size. This can lead to superficial haemorrhages and leakage. Coats’ may cause strabismus (squint).
The condition is diagnosed by the appearance of the back of the eye and by Fluorescein Angiography. Angiography clarifies the eye by injecting dye and then taking photos of the circulation of the back of the eye.
Certain rare complications that might involve the macular regions (responsible for central vision) are increasingly treated successfully with the Argon laser.
Surgery, usually by light (photocoagulation) or extreme cold (cryotherapy), can be used in some people.
If applied early, treatment may be successful in preventing progression and in some cases can improve vision but this is less effective if the retina has detached.
Although it is not uncommon for the condition to lead to retinal detachment, in many cases progress of Coats’ disease halts of its own accord and without treatment.
RNIB is not aware of a specialist group offering information on Coats’ disease although a range of services exist for people with sight difficulties and related problems.
1. LOOK is an organisation which seeks to identify sight related support groups and put parents in contact. They have regional representatives. Look's national office address is
LOOK UK
Queen Alexandra College
Court Oak Rd
Harbourne
Birmingham B17 9TG
Telephone 0121 428 5038
2. RNIB Education Service is happy to discuss the ways in which children with severe sight problems can achieve their potential and to identify local support for families with visually impaired children. (
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Has anyone had retinoblastoma?
I was diagnosed with it at 4 years old. I've had a prosthetic left eye for 14 years now. I'm just looking for people to exchange stories with. I've never really talked to anyone who suffered from the same thing or has a prosthetic eye either. So, if you have and you're interested in sharing stories, good and bad, let me know.
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You might like to join an online email group of Retinoblastoma survivors . . . perhaps you can exchange stories and information with others:
ACOR: Retinoblastoma Survivors Support Group
http://listserv.acor.org/archives/rb-survivors.html (
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anyone know what a CT scan would show with retinoblastoma?
Computed tomography (CT) scan is a valuable tool in the differential diagnosis and management of retinoblastoma. Most retinoblastoma patients studied with high resolution computed tomography have intraocular calcification demonstrable in at least one eye. Over 80% of tumors shows evidence of calcification on CT scan. The degree of calcification appears to depend upon tumor size; only small tumors are devoid of calcification. In patients under three years of age in whom a retinoblastoma is suspected, the presence of calcification on CT scan is virtually diagnostic of retinoblastoma. Ct scan also helps the doctor ascertain the size of the tumor, involvement of the optic nerve and surrounding structures and a CT scan is also useful in ruling out retinoblastoma. (
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Could this be Retinoblastoma?
I took this picture and noticed the yellow/golden pupil. Ive heard of Retinoblastoma in kids before, but not in adults, though i know it can be in rare cases that adults become diagnosed with the disease.
Can anyone proffesional tell me wether there is a risk of Retinoblastoma through looking at the photo?
follow the link. http://www.flickr.com/photos/38730415@N03/3560351288/
Many Thanks.
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Retinoblastoma is a very aggressive ocular tumor. It nearly always occurs in children and requires immediate attention. The chances of it being retinoblastoma at your age are very very small. There are many other things that can also cause this appearance in photos. Things like having a difference in prescription between the two eyes and a large uncorrected prescription can also cause this appearance. The best thing to do, is go to see an optician to know for sure. Retinoblastoma can easily be detected in a routine eye examination (
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Have you heard of retinoblastoma?
I want to know how many people actually know about this type of cancer. I'm looking forward to the responses.
If it's possible, I would like responses from everyday people, not doctors, as I'm sure you have learned abou this disease. :))
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If you want to know the number of people who knows about this condition you should consult a statistics page. If you want to know about the disease here goes: RB is a malignant tumor of the retina, due to cellular mutation, presenting itself mostly in kids younger than 6 years. It is mostly diagnosed in kids between 1 and 2 years. Depending on the size and the dissemination of the tumor, the condition can be treated by laser surgery or chemotherapy. Prognosis depends on the same two factors. (
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