FAQ - Proteinuria
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Proteinuria ....What does this really mean?


Proteinuria... this was what was on my lab reports I got though the mail.
My Doctor wants me to do a 24 hour ,pee in a jug test. Should I be worried about this. Does this mean there is something coming on. My doctor is out of town ,so I can't ask him.
I'm not a diabeteic. But my 16 year old son is a type 1.
I don't have high blood pressure. Or any swelling.No foamy pee. Thats why I;m so confused, But I do have a strong family history of kidney problem.
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Proteinuria-presence of protein in urine is an indication of some renal related diseases.but it could be due to pre-Eclampsia or toxemia in pregnancy.your doctor wants to be certain of his diagnosis that's why he ordered for 24 hour urine collection for creatinine clearance to determine the kidneys excreatory functioning.  (+ info)

Ever heard of proteinuria?


I am waiting to go to a kidney specialist to get the results.
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Yes, it means that protein is in the urine. Normally, protein molecules are too large to pass through the glomuleri filters in the kidneys to reach the urine. Some trace protein excretion is normal, but over a certain point it is considered proteinuria.

Good luck w/the kidney specialist. Unless you haven't done so already, you will probably have to repeat the test.  (+ info)

Is pulmonary stenosis and proteinuria related?Please answer! HELP ME?


i suffered from pulmonary stenosis since i was born. i had treatment when i was 2 years old. now i am 16, i did urine test yesterday at the hospital. as a result, the doctor said there's protein in my urine. my kidney "leaks" . the result is ALBUMIN : +1 . i did some research through the internet and i get to know that i suffer from proteinuria. so, what should i do? is pulmonary stenosis and proteinuria related?
Please help me to answer this question, my life is in danger :(
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Congenital pulmonary stenosis and proteinuria are not related at all to one another. A small amount of protein in the urine can be normal. A +1 reading on the urinary dipstick is actually not significantly elevated. A small amount of protein in the urine can occur temporarily in healthy individuals and this leads to no long term problems. Exercise and postural changes can lead to a small amount of proteinuria in some healthy individuals. Therefore you should have this rechecked in the future and if it resolves then it is nothing to worry about. Protein can also be present in the urine secondary to the presence of white or red cells. If you had > 5 WBC or RBC, then this is the likely cause and nothing to worry about.

Proteinuria can be a sign of kidney disease also, but kidney disease is associated with more significant proteinuria than you have. Further testing can be performed to further quantify your proteinuria. This is usually done by a urine protein/creatinine ratio or a 24 hour urine sample. Your life is certainly not in danger. Even if this was secondary to a kidney condition, it would be unlikely to lead to any immediate problems at this level. Continue following with your doctor regarding this. Also be careful about doing your own research on the internet. I am guessing most of what you will find regarding this would be irrelevant to your case.  (+ info)

Diabetes? Kidney Disease/failure? Proteinuria? Ovarian Cyst? Something else? Any information, symptoms? Thanks


I've had bad pains in my lower left side since Feb. 08 and was told it was most likely an ovarian cyst (they run in my family) I finally got an ultrasound and got the results back today: All clear! (although that doesn't help or solve the pain!) Recently my pain has moved farther up and into my lower back at times. My doctor then informed me that I had a lot of protein in my urine and I had a lot in my urine for my Feb. 08 visit as well. She suggested I may have diabetes, kidney disease, or proteinuria and ordered blood and urine tests to be done and ordered me to stay out from work for the next week. While we're waiting to be able to get the tests completed I'm trying to research how serious any or all of this is and what the symptoms or warnings are for each. Also, What should I be on the lookout for in an emergency situation? I read up on ovarian cyst and I'm at a loss now that it's something completely different. How serious are these diseases? Anything is appreciated! Thanks!!
Also, any information on what tests may be run and what to expect please let me know. I'm totally clueless on all of this and my doctor was not willing to answer many questions at all.
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Most likely, the proteinuria was an incidental finding -- it was picked up "by accident" when your doctor did a urine dipstick test as part of the workup for the back pain.

The kidneys (most of us are born with two) have no nerve endings, so they only cause pain when their outer covering (called the capsule) is stretched due to inflammation or swelling. That's why most kidney diseases are silent / asymptomatic until they become quite advanced.

The kidneys' main function is filtering blood and getting rid of waste products (and excessive fluids) in the form of urine. Since most proteins are useful, normal-functioning kidneys will not let proteins go to waste in the urine.

The presence of large amounts of protein in the urine (called proteinuria) is therefore a sign of kidney disease. Diabetes is the leading cause (by far) of kidney disease in North America, and can certainly cause proteinuria. However, just know that there are many other kinds of kidney diseases which also cause proteinuria.

Sometimes even people with normal kidneys can spill proteins into the urine for a short amount of time (for example, after vigorous exercise), that's why your doctor wanted to repeat the urine test for protein -- to see if it was a one-time thing.

More advanced tests can also be done on the urine to help determine the cause of kidney disease. For example, your doctor may want you to collect urine for 24 hours, or collect a sample after sleep while another after you've been up for a few hours.

The blood tests can achieve a few things:
1) Measure your kidney function: In moderate or severe kidney diseases, a test called "creatinine" becomes eleveated.
2) Measure your blood sugars: People with diabetes will have high blood sugars, even after fasting overnight.
3) Check consequences of kidney dysfunction: some minerals like potassium and phosphorus become out of balance with kidney failure
4) Check for some specific causes of kidney diseases (although there are many many diseases with many many different tests, and often only kidney specialists called nephrologists know what test to order for which disease)

Finally, how serious this is depends on how advanced the kidney disease is (if you have one at all). Since you haven't had much in the way of symptoms (again, your back pain is most likely NOT related to your kidney disease), chances are your kidney diseases are still mild, in stages 1 to 3. However, some kidney diseases can progress to End-Stage Renal Disease (ESRD), at which point dialysis becomes needed to sustain life.

The test results will become available in a few days. If necessary, your doctor will refer you to a kidney specialist for further management. But for now, just sit tight -- no need to freak yourself out until the test results return.

In case you are wondering, at least 10% of the population have some degree of chronic kidney disease (http://jama.ama-assn.org/cgi/content/abstract/298/17/2038), but many don't even know it. So you are not alone!  (+ info)

Does proteinuria cause muscle loss?


of prevent you from gaining muscle?

I'm quessing yes....
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i know that proteinuria can be a result of muscle loss and more importantly, of renal problems.  (+ info)

Severity of my proteinuria?


Dear Friends,
10 days back, I have gone for general medical checkup. I have undergone Ultrasound of abdomn also. My doctor telling i have protein in my urine. That to 3g in 24 hrs sample. He suggests me to proceed to buyopsy before further treatment.
Please clarify me, what is the severity now. Is it curable.
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Proteinuria,protein in urine.?


30 mg /dl . This is what came back in my urinalysis. Is this very high?
And what is the normal level of protein in urine?
Could not drinking enough water cause this?
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Does hypertension and/or kidney stone(3.3mm) cause proteinuria?


Two weeks ago, I was diagnosed to have 3.3mm stone/lithiasis in my lower left kidney calyces. Also my blood pressure varies from 120/90 to 140/90. I'm 23 y/o male. Protein in the urine varies from trace to 3+. I'm afraid that this leads to glomerulonephritis or end-stage renal failure other than just hypertension or kidney stone. In my case, is it treatable/curable? Please enlighten me. Thank you!!!
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what does proteinuria mean?


Introduction

Proteinuria describes a condition in which urine contains an abnormal amount of protein. Proteins are the building blocks for all body parts, including muscles, bones, hair, and nails. Proteins in your blood also perform a number of important functions: protecting you from infection, helping your blood coagulate, and keeping the right amount of fluid circulating through your body.

As blood passes through healthy kidneys, they filter the waste products out and leave in the things the body needs, like proteins. Most proteins are too big to pass through the kidneys' filters into the urine, unless the kidneys are damaged. The two proteins that are most likely to appear in urine are albumin and globulin. Albumin is smaller and therefore more likely to escape through the filters of the kidney, called glomeruli. Albumin's function in the body includes retention of fluid in the blood. It acts like a sponge, soaking up fluid from body tissues.

Inflammation in the glomeruli is called glomerulonephritis, or simply nephritis. Many diseases can cause this inflammation, which leads to proteinuria. Additional processes that can damage the glomeruli and cause proteinuria include diabetes, hypertension, and other forms of kidney diseases.

Research shows that the level and type of proteinuria (whether the urinary proteins are only albumin or include other proteins) strongly determine the extent of damage and whether you are at risk for developing progressive kidney failure.

Proteinuria has also been shown to be associated with cardiovascular disease. Damaged blood vessels may lead to heart failure or stroke as well as kidney failure. If your doctor finds that you have proteinuria, you will want to do what you can to protect your health and prevent any of these diseases from developing.

Several health organizations recommend that some people be regularly checked for proteinuria so that kidney disease can be detected and treated before it progresses. A 1996 study sponsored by the National Institutes of Health determined that proteinuria is the best predictor of progressive kidney failure in people with type 2 diabetes. The American Diabetes Association recommends regular urine testing for proteinuria for people with type 1 or type 2 diabetes. The National Kidney Foundation recommends that routine checkups include testing for excess protein in the urine, especially for people in high-risk groups.


Who Is at Risk?

People with diabetes, hypertension, or certain family backgrounds are at risk for proteinuria. In the United States, diabetes is the leading cause of end-stage renal disease (ESRD), the result of progressive kidney failure. In both type 1 and type 2 diabetes, the first sign of deteriorating kidney function is the presence of small amounts of the protein albumin in the urine, called microalbuminuria. As kidney function declines, the amount of albumin in the urine increases, and microalbuminuria becomes full-fledged proteinuria.

High blood pressure is the second leading cause of ESRD. Proteinuria in people with high blood pressure is an indicator of declining kidney function. If the hypertension is not controlled, the person can progress to full renal failure.

African Americans are more likely than white Americans to have high blood pressure and to develop kidney problems from it, even when their blood pressure is only mildly elevated. In fact, African Americans ages 25 to 44 are 20 times more likely than their white counterparts to develop hypertension-related kidney failure. High blood pressure is the leading cause of kidney failure among African Americans.

Other groups at risk for proteinuria are American Indians, Hispanic Americans, Pacific Islander Americans, older people, and overweight people. People who have a family history of kidney disease should also have their urine tested regularly.


What Are the Signs of Proteinuria and Kidney Failure?

Large amounts of protein in your urine may cause it to look foamy in the toilet. Also, because the protein has left your body, your blood can no longer soak up enough fluid and you may notice swelling in your hands, feet, abdomen, or face. Alternatively, you may have proteinuria without noticing any signs or symptoms. Testing is the only way to find out how much protein you have in your urine.

What Are the Tests for Proteinuria?

To test for proteinuria, you will need to give a urine sample. A strip of chemically treated paper will change color when dipped in urine that has too much protein. A more sophisticated chemical analysis is needed to find smaller amounts (microalbuminuria). The most dependable measure of proteinuria requires you to collect your urine for 24 hours.

You will be given a special container and instructions for starting and stopping the collection and for storing the container.

How Is Proteinuria Treated?

If you have diabetes, hypertension, or both, the first goal of treatment will be to control your blood sugar and blood pressure. If you have diabetes, you should test your blood sugar often, follow a healthy eating plan, take your medicines, and get plenty of exercise. If you have diabetes and high blood pressure, your doctor may prescribe a medicine from a class of drugs called ACE (angiotensin-converting enzyme) inhibitors. These drugs have been found to protect kidney function even more than other drugs that provide the same level of blood pressure control.

People who have high blood pressure and proteinuria but not diabetes may also benefit from taking an ACE inhibitor. The National Heart, Lung, and Blood Institute recommends keeping blood pressure below 125/75 mm Hg for people with proteinuria greater than 1 gram per 24 hours.

In addition to blood sugar and blood pressure control, the National Kidney Foundation recommends restricting dietary salt and protein. Your doctor may refer you to a dietitian to help you follow a healthy eating plan.  (+ info)

why in Nephritic syndrome, proteinuria is less (<3.5 g/day) compared to nephrotic syndrome (>3.5 g/day)?


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