causes of low ESR in polycythemia and in sickle cell anaemia?
ESR is the measure of the ease with which red blood cells settle to the bottle of a glass tube. The result is reported as the height of the clear part of the blood (plasma) above red blood cell stack after 1 hour of settling. So a higher number implies faster settling, less blood. A lower number indicates slower settling or more blood.
Also, red cells have a charge on their surface creates a certain degree of repelling force. Proteins in the blood neutralize this force to a degree proportional to the amount of these proteins in the blood and allow faster settling, higher ESR.
So in polycythemia where there is more blood, the ESR would be at the low end.
In anemias (of which SC is just one) the ESR would be in the higher end (I can't comment on the affect of sickling on settling, but the sickles cells are much smaller than a regular cell so the ESR would be expected to by higher, however their shape may interfere with settling, thus reducing the ESR).
Also, if there is any significant inflammation, cancer or other condition which produces more of certain types of proteins, the ESR would be higher. (
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Can you/do you get an elevation in band cells with polycythemia or leukemia?
Yes, you get an elevation of band cells (also called a shift to the left) with both polycythemia and leukemia. But polycythemia is more commonly associated with band cells. (
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any other children with polycythemia?
may son is ten and has had it since birth. i just want to know if any other kids have it, and what treatment they get or tired. thanks ,we go to st jude every month to get blood taken out. this is very hard on him, but we are out of options.
thank you, for you answers. there is no medical reason why he has it, and st jude said he is the only child his age to have. thank you again
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I don't know of any children but my dad has had it for years. Blood thinners do not work on this condition and the doctors told him the only way to ease the problem is to have a pint of blood removed every so often. While it could be other options out there, we have yet to find any that are any simpler than just getting the blood removed once a month. My father is now on dialysis. They say once you start dialysis, your body doesn't make any more blood that you keep what you have. However, he has been going to dialysis for a year now and still has to get blood removed.
My thoughts are with you and your child as you battle this condition. Hopefully, someone knows something I don't and there is a better way. However, we have been doing the same as you.....travelling once a month to get blood taken out.
Good Luck to you! (
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what is the best treatment for polycythemia vera,donating blood or donating platelets?
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Is anyone here familiar with Polycythemia Vera?
I have been diagnosed to have this at age 28. Exactly two years ago. If someone have this can you link with me?
Im on Hydroxyurea therapy (a bone marrow suppression drug) Anyone from yahoo users have this?
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I'm surprised that you are taking hydroxyurea therapy. I think phlebotomies are usually more than sufficient to control the disease and have very few side-effects.
Anyway, I assume that your doctor knows well what he is doing. Hydroxyurea is a perfectly acceptable therapy but there may be other alternatives to consider. I suppose you have already discussed this with him... (
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I have polycythemia, a high red blood cell count. Treatment is to donate blood. I want to sell mine. Can I?
My doctor recommends I give blood 8 times a year. This is uncomfortable, time consuming and leaves me wasted. If I was giving plasma I could make $200 a month, but selling blood is illegal I think. Is there a way I can make some badly needed cash. It seems like my blood should be worth as much as my plasma.
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I did search & could not find any blood selling sites in USA (only Mexico, Iraq & China). Try selling plasma without them retuning your blood cells afterwards. May need a doctors note to show this is a medical need to only go through step one of plasma removal.
Maybe there are colleges, labs, hospitals that will buy your blood for research purposes. Again, have doctor referral for such to show them you are serious. So check these local areas out. (
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Does anyone have Polycythemia Vera or secondary?
A family member has this and I was wondering if anyone here did and how were they doing? I also would like to know the treatments they were taking. Thanks
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Please see the web pages for more details on Polycythemia vera. (
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I need doctor specializing in polycythemia?
Do research on this condition on the Internet you should be able to find a doctor that specializes In the condition there. (
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I have just been diagnosed with polycythemia what is it?
I know its not polycythemia vera but polycythemia whats the diffrence
I want to know what the diffrence is between polycythemia and polycythemia vera eveything you look up only relates to the second one and I know its not that
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I used to have polycythemia back in college. I used to take iron supplements for months and when I have had my hemoglobin checked it was higher than normal. Polycythemia is when you hemoglobin levels is above normal levels.
What I did was to stop my iron supplement completely and after a few months my hemoglobin has gone back to normal. some people with really high levels of hemoglobin, they bleed them. It can cause thrombosis if you have a high level of hemoglobin because the blood is too thick. It really depends on how high your hemoglobin is. they should take another hemoglobin check just to confirm if this is really high. (
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what kind of a blood disorder is polycythemia vera?
Polycythemia is a myeloproliferative disorder of unknown etiology, characterized by abnormal proliferation of all hematopoietic bone marrow elements and an absolute increase in red cell mass and total blood volume.
*Associated frequently with splenomegaly, leukocytosis, and thrombocythemia (
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