What would happen if a body had an excess of a gallon or more of insulin in their system?

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Would they go into coma or death or survive?
actually I'm not craving attention. so go take a hike .
Impossible. They would be dead.  (+ info)

why may insulin coma occur?

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i am a nursing student and am researching dm types 1 and 2 all help appreciated thanx
nikki
An Insulin coma is when a Diabetic's blood sugar has gone too low. (it isn't always insulin that causes the coma, too much excise and other activities than involve fitness can lower the diabetic's BGL (Blood Glucose Level)) When the diabetic has gone into this coma there are a few ways to treat it.

#1. A Glycogen Pen. Basically, it's a needle filled with concentrated sugar. This is injected anywhere into the diabetic (best on the tummy or leg (anywhere with fat)) This is the most extreme treatment. but should work every time.

#2. Honey. Applying honey to the gums (mouth) of the diabetic may bring them out of the coma, but this is usually not the best treatment.

You should also disconnect the diabetic's pump, if they are wearing one. The pump is basically the size of a pager and usually worn on their belt or in their pocket. you should SUSPEND the pump (by following these directions. press ACT, go down one to SUSPEND, then pressing ACT again, then once more) or, cut the line connected to the diabetic.

Note: The diabetic is safe during this time. the body has just shut itself down to protect itself.

I hope I haven't overloaded you with information
  (+ info)

how low glucose level can be before going into coma?

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i have had my blood sugar drop into the 50s and been very frightened about how i feel. am trying to get a better handle on my insulin doses, but lapse completely for weeks at a time now and then. takes a week or so to get it back down to normal.
Every person is different because I have had some people at 28 talking lucidly but I have also had people around 33 who were completely unconscious. When you feel dizziness, cold sweat, feeling slightly confused, you need to quickly check your blood sugar and then immediately eat something to bring it back up before it has a chance to drop any more.  (+ info)

Husband's blood sugar is 300...he is currently on Metformin. Time to move up to insulin? ?

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I KNOW he should be asking his doctor and he will next week at his appointment if he has not lasped into a diabetic coma by then...I am just trying to get some info before hand. Any help appreciated! Thanks
Your husband needs to be eating a low fat, high protein, low carbohydrate diet all of the time to help keep his BG from getting so high. He should limit white bread, rice, pasta and potatoes, as well as anything with sugar, no cake, candy, cookies, cola, etc.

Right now he should go walk for half an hour even if slow and drink lots of water to flush the sugar out of his system.

Hope this helps.  (+ info)

what is the name of the woman who died this week, aged 76, who has been in a coma for years. Foul play suspec?

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Her husband was suspected of giving her an overdose of insulin.
Sunny von Bulow http://news.yahoo.com/s/ap/20081206/ap_on_fe_st/obit_von_bulow  (+ info)

How does insulin work in the body at the cellular level?

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How does insulin work in the body at the cellular level?
How does insulin work in the body at the cellular level?
What gives it its steroidal properties?
I know that insulin increases cell tranlsation, which means more protein is produced, which builds muscle and causes weight gain, is there a way to stop this weight gain? Like maybe a chemical we can add to the insulin that will not affect the insulin, but will prevent weight gain, or prevent translation in cells, while not affecting normal protein production.
Glucose cannot penetrate the cell wall unless it is attached to molecules of insulin. The sugars and starches you eat are converted to glucose, which enters your bloodstream to be transported to the cells.. There are cell receptors in each cell that responds to the insulin and allows the glucose to be transported into the cell where it is turned into energy.

When there is too much sugar, and that means carbohydrates too (carbohydrates are just long chains of sugar linked together), the cells are getting too much and become insulin resistant. The body thus produces more insulin to try and push the sugar into the cells. This insulin resistance will turn into type II diabetes.

Cut down on carbs will prevent the weight gain.  (+ info)

How gradual does one have to be when changing insulin schedules?

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My boyfriend started taking insulin (10CCs) Tuesday, at the doctor's office, they started at 10am. The last few days he has been taking his insulin around 10am. However, he prefers to take insulin at night, because of his work schedule. Is it safe to take Thursday's insulin three hours earlier in the morning, say, around 7am, and then again, Thursday night around midnight, take "Friday's insulin" then Saturday night, take the insulin around 11pm? And continue to take the insulin at 11pm every night from then on. Or, should the change be more gradual than that? How exact do you have to be about taking it at the "same time" every day?
He might have to patch the insulin he's taking. When I took insulin shots, they had to be at pretty much the same time, since insulin only lasts a certain amount of time. For example, if you have three types of insulin, A B and C, and A lasts twenty four hours, B lasts 8 and C lasts four, your boyfriend might use A normally but patch with B and C to change teh time he takes his insulin. Otherwise, he could go low, which really sucks (if he hasn't had a low yet, lucky him...). So, basically, he should talk to his doctor.

PS I think that Lantus lasts twenty four hours, NPH lasts about 8 and humolog/novolog last about four, but don't quote me on that.  (+ info)

How does the sensitivity of target cells to insulin signaling affect insulin release from the source cells?

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Insulin resistance is a condition where normal amounts of insulin do not elicit a normal degree of insulin response. In insulin resistant individuals (without diabetes), the concentrations of blood insulin are higher than normal. Describe all relevant events.
First, insulin resistance is the result of 'metabolic syndrome' which is a condition that results from excess carb intake, poor nutrient intake, and inadequate amounts of exercise to burn off the excesses. Insulin resistance is merely a term to describe the condition of someone who is on their way from just having metabolic syndrome to becoming full blown (type two) diabetic. When target cells become less responsive to the signalling of insulin and blood sugar begins to build up, the natural response is for the source cells to produce more insulin in an effort to move the glucose from the blood into the cells. After reading the following source material, you will have a clear understanding of all of the relevant events.  (+ info)

How does long lasting insulin work, how does the insulin get into the system once injected?

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I like to know how things work but don't seem to be able to find the answer to this one. I started on Levemir injections recently and everything I read is about the insulin, why I need it and where and how to inject.

If I take tablets I understand how they get into the system but where does the long lasting insulin go from the injection site. Is it circulating in the blood, stored in the liver or elsewhere.

Can anyone tell me or know of a good website with more information.
When you inject insulin, it breaks down and then gets absorbed into capillaries and into the blood stream. The 1st site listed explains how insulin (from the pancreas) goes through the blood stream and how it enters cells and what happens after that, and the 2nd site listed explains how insulin that is injected gets into the blood stream. Good question, I didn't really understand the whole process myself and I inject also!  (+ info)

What causes cells to become insulin resistant?

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Is insulin resistance reversible? I am prediabetic ( in the form of impaired glucose tolerance) so I wanted to know if the cells in my body that have become insulin resistant will become normal again. I exercise regularly and eat small meals, I eat an average of about 120 or less carbs a day, I am in excellent shape (5'3' and 102lbs), and I am planning on taking supplements that lower blood sugar. So can my cells ever become non insulin resistant after doing all that?
Your body mass index is 18.1 kg/M2. If you are age 25 or older this would represent 'underweight' status. If you are younger than age 18 your will be above the 5th percentile which would be considered acceptable. There is a correlation between weight and insulin resistance but clearly that is not your case. This emphasizes the fact that diabetes is not simply a condition of the obese. Quite honestly we have no idea what the precise nature of insulin resistance is. If someone is over-weight - which you are not - reducing weight decreases insulin resistance. I doubt that your insulin resistance will be able to be reversed but I wonder where the diagnosis of insulin resistance came from. This requires rather sophisticated testing. Having 'glucose intolerance' or being a 'pre-diabetic' most definitely is not synonymous with having insulin resistance. I do not use terms such as glucose intolerance, pre-diabetic, or borderline diabetic as I believe that these terms miss the point entirely. There is an approximately 10 year lead-in time of pathophysiologic damage prior to the glucose becoming consistently elevated and being diagnosed with type 2 diabetes which I suspect is what is at issue here rather than type 1 diabetes where insulin resistance does not play a role. I do not have specific information but I must wonder from what you are saying if you are an 'early' diabetic. These individuals do not necessarily require pharmacologic intervention. The first step is typically a low glycemic index diet, weight loss (not an issue in your case), and exercise. It sounds as if you have all of these in order. I strongly believe that type 2 diabetes should be sub-divided into type 2A and type 2B. 2A would be type 2 diabetics with a 'lean' body mass index - which would be your case. 2B would be type 2 diabetics with a body mass index of greater than 30 kg/M2 - assuming that they are older than age 25. I start 2A diabetics - when pharmacologic intervention is required - on insulin. I start 2B diabetics - when pharmacologic intervention is required - on oral medications with the caveat that most type 2 diabetics will be on insulin within 10 years of diagnosis. I do not know of any so-called 'supplements' that lower blood glucose. Please do not be upset that I am suggesting that you might have early diabetes as I have far too little information to offer an informed opinion. Indeed one of the problems in answering questions in this forum is that people do not provide enough information. If you provide me with additional and more detailed information I will try to be of further assistance. I wish you the very best of health and in all things may God bless.  (+ info)

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