FAQ - Endometrial Hyperplasia
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complex endometrial hyperplasia?


i was just diagnost with this he said that it is not cancer but precancerous i am not sure what he meant by that, he said i can have my uterus removed or have a d&c and biopsy every six months what are the risks of it going to be cancer? i thought he said a long time , like 5 to 10 years and he didnt seem all that concerned should i be?
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Endometrial hyperplasia is the medical term for unusual or excessive cell growth in the inner glandular lining of the uterus, also called the endometrium. Most of the time, endometrial hyperplasia is uncomplicated and easily treated by your ob/gyn provider, with minimal intervention.

However, there are times when uterine hyperplasia can get worse, leading to atypical and precancerous cellular changes. This is why any woman with hyperplasia is considered to be at a higher risk for cancer than one without. And even though this sounds scary, especially if you’ve just been diagnosed with a thickened endometrium, you should know that there are many steps between hyperplasia and full-blown uterine cancer — and early identification and intervention for uterine abnormalities is highly successful.

Good luck. Make sure you see your OB-GYN regularly.  (+ info)

I was diagnosed w/ endometrial hyperplasia on sept 11th '08 and given Provera 5mg. Started period on sept 27?


which is semi-normal. I usually get it on the first or of the month. It started out a bit heavy but got heavier as the weeks went by. In the past week and a half, it lightened a substantial amount. The problem is it is now October 30th and I haven't stopped bleeding. Has anyone ever experienced this. Should I be worried and make and appointment w/ my doctor? He also said that Provera was suppose to stop my periods completely? Help?
Sorry, I'm on 10 mg...not 5
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I took provera 10 mg and believe me girl, I KNOW what you're going through. I was on my period for 15 days and then it stopped. Unless it is still really going, I wouldn't worry too bad. I would call and ask if this was normal. This is also a symptom of endo hyperplasia... Good luck. Also, I'm pretty sure provera does not stop your periods. that's weird he told u that.
  (+ info)

What is the difference between hyperplasia and dysplasia- and can anyone give me a reference for it?


I can't seem to find a book or journal article that specifically defines the difference between dysplasia and hyperplasia- any help would be much appreciated!
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Hyperplasia is a general term referring to the proliferation of cells within an organ or tissue beyond that which is ordinarily seen

Dysplasia is a term used in pathology to refer to an abnormality of development.

Hyperplasia = excessive normal cells which are benign.
Dysplasia = excessive abnormal cells which can become malignant.  (+ info)

What are they symptoms of a ruptured Focal Nodular Hyperplasia?


I was diagnosed with Focal nodular hyperplasia, which is a type of benign tumor on the liver. I've been having a lot of pain lately. Along with tingling sensations that just started today. I was wondering if anyone knew the symptoms of a ruptured Focal nodular hyperplasia. I can't find any info online about it. Thanks so much.
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Pain is the only symptom. If you look under
"presentation"of this web page, you will see it mentioned.
I definitely would have it checked out right away. From the second article that
talks about rupture...it is very rare.
http://emedicine.medscape.com/article/368377-overview
http://www.sma.org.sg/smj/4602/4602cr2.pdf
Usually what symptoms a patient has
with a tumor, will only increase if there
becomes a problem with it.

Wish I could tell you more.  (+ info)

What does endometrial echocomplex demonstrating a proliferative morphology mean?


I had to have a pelvic ultrasound done because I was getting some pain which my doctor thought may be due to an ovary cyst. Turns out I have a corpus lupus cyst. Also on the ultrasound it states as follows The endometrial echocomplex measures 1.5cm demonstrating a proliferative morphology. I have tried looking it up on several websites without success. Any helpful comments would be appreciated.
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It's an abnormal, rapid cell growth on the endometrium or lining of the uterus. Proliferative morphology sounds like it means that this growth is still actively growing.

Basically, it sounds like a growth or possibly an unusually thick endometrial layer (the lining of the uterus that usually thickens at various points throughout the month.)  (+ info)

What is the expected life span of endometrial cancer which has metastasized to the lungs and brain?


My mom has been diagnosed last May with endometrial cancer and underwent hysterectomy and radiation therapy. Just recently, we found out that it has metastasized to the lungs and brain. It breaks our heart to see her suffer much but at this time, there really is no cure available. She is now undergoing palliative radiation treatments to help manage the pain. Just wanted to have an idea how much time we have left with her?
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Wow. This is rare and very unfortunate. We are sorry for you in this difficult time.
Here's data looking at people in similar situations from a 2003 Canadian study.
"Between January 1991 and March 2003, there were 1295 women referred to the London Regional Cancer Center with the diagnosis of endometrial cancer, and eight of these women (0.6%) developed brain metastases. Treatment and clinical outcomes were analyzed.
Three patients had no other evidence of systemic disease, while five had disseminated disease. Four patients had a single brain metastasis, while four had multiple lesions. Seven patients received whole brain radiation therapy in addition to systemic steroids, of which six had temporary improvement or resolution in symptoms. Median survival following diagnosis of brain metastases was 3.5 months."

This study of almost 1300 women with endometrial cancers found only 8 who developed brain involvement. I did not see a person like this in 20 years as a cancer specialist doctor. Their experience with the 3 to 4 month survival is not a prediction - since it is based on only 8 people.

Doctors can never predict survival months ahead of time. When it gets down to the last days, it is relatively easy for experienced nurses and doctors to see the end coming - but family members can see that too. You will know when things are headed downhill. Enjoy the good time as much as possible.

http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WG6-4C0TD88-2&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&_docanchor=&view=c&_searchStrId=978008158&_rerunOrigin=google&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=a224796b99ddb04c54434c46aa78a7b5  (+ info)

What are the chances of a very thick endometrial lining being cancerous in a post menopausal woman?


My 58 yr old friend had a pelvic sonogram and the doctor said that her endometrial lining is 5 times as thick as it should be and is sending her to a Gyn-oncologist. Does this mean that he is pretty sure that she has cancer?
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They call that a hyper-proliferative endometrium.
It does not mean cancer. It means she is not shedding her endometrium probably because she does not have her period.
I did this same thing about 10 yrs ago. They biosied my endometrium and put me on high doses of progesterone.
She will need to follow up with her gynecologist.  (+ info)

What does it mean when your pap result is atypical endometrial cells?


I have had an endometrial biopsy and transvirginal ultrasound done but am still waiting the results.The waiting is murder. It's all I can think about. Have I got cancer?
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I'm sorry you're feeling so anxious. The cells in the cervix are some of the fastest growing in the body. The cells in the walls are constantly being grown and shed. As a result of the fast renewal some cells may be created that are abnormal. It is quite common for women to return atypical results from their pap smears without it being cancer. I know it's a worrying thought but the earlier these things are found the better. Take care.  (+ info)

How would you prevent intimal hyperplasia?


Intimal hyperplasia is the universal response of a vessel to injury and is an important reason of late bypass graft failure, particularly in vein and synthetic vascular grafts.
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Low dose beta radiation seems to be a goer.
Antioxidants seem not to be useful.

Femoropopliteal PTFE (polytetrafluoroethylene) bypass with distal AS interposition provides improved graft patency and limb salvage rates when compared with those published in the literature for PTFE bypass without the (distal arterial segment) AS.  (+ info)

How pregnant could you be in the proliferative endometrial stage?


I had a Endo Bx without a pregnancy test done and am worried I may have been pregnant (had unprotected sex 2 times month prior). The results showed I was in the 'proliferative endometrial stage'. My tubes are tied and I'm 52 but I've understood it can still happen at that age.
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It is hard to say I am no expert- but the "proliferative endometrial stage" of your cycle all that means is that your endometrium (the lining of your uterus) is proliferating (to grow or produce by multiplication of parts, as in budding or cell division) which means the lining of your uterus was in the process of building up & getting thicker. This happens in the first half of your menstrual cycle (follicular phase) just after your period, BEFORE ovulation. You can't get pregnant unless sperm meets egg, and they can't meet if you haven't released the egg yet! There is no way you could have been pregnant, it was too early in your cycle even if your tubes weren't tied.. take a deep breath and relax.  (+ info)

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