FAQ - Cholestasis
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36 weeks 1 day and have Cholestasis. Anyone had same problem?


I had lot of contraction last night and went to hospital and stayed couple of hours to monitor the baby since I have this liver disorder but then the contraction became weaker and I decided to go home. Since I came home, I had weak contraction so I force myself to sleep and today I'm having them a bit more stronger. I'm just wondering if they gonna induced me or what is gonna happen since I'm getting so much contraction and I have cholestasis. Did anyone have the same problem?
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hiya i have the same liver problem as you and i've been told that they normally tend to start you off at 38 weeks pregnant as they don't like you going over full term as the chances of still birth are higher they will try and keep you going unti at least 37 weeks just hang in there and good luck  (+ info)

intrahepatic cholestasis? Does having intrahepatic cholestasis mean you have Hep C?


I was exposed to Hep C like 6 yrs ago and tested neg then but with my daughter i had intrahepatic cholestasis, and just now realized it can be tied in with Hep so how serious is it i had her 18 months ago. So does having ICP mean you have Hep?
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No

Here's what I found on about.com

Intrahepatic Cholestasis of Pregnancy - ICP
By Heather Brannon, MD, About.com
Updated: September 25, 2004

Pregnancy Classes

Intrahepatic cholestasis of pregnancy (ICP) is the second most common cause of jaundice in pregnancy. Its prevalence varies from country to country. In the United States, Switzerland, and France ICP occurs in less than 0.5% of pregnancies. However, ICP occurs in 11.8% to 27.6% of pregnancies to women of Araucanian Indian descent in Chile.

Appearance

The most common symptom of intrahepatic cholestasis of pregnancy is itching which typically develops in the third trimester of pregnancy. The itching begins on the palms and soles, and then spreads to the rest of the body. The rash of ICP is caused by scratching the intensely itchy skin. Jaundice occurs in 10% to 15% of cases and typically develops 2 to 4 weeks after the itching starts. After delivery, both itching and jaundice resolve spontaneously. ICP does recur with subsequent pregnancies in 40% to 50% of women.

Cause

Intrahepatic cholestasis of pregnancy is caused by an impairment of bile secretion in the liver. As the bile backs up in the liver, the level of bile acids increases in the bloodstream. These bile acids are deposited in the skin causing the intense itching. Cholesterol, triglyceride, and bilirubin levels are also increased.

Several complicated mechanisms have been proposed to explain this impairment of bile secretion, but it appears that genetic and hormonal factors are involved. Women who have a mother or sister who has had ICP are at a higher risk of developing this condition. Also, estrogen interferes with the clearance of bile from the liver, and progesterone interferes with the clearance of estrogen from the liver.

Related symptoms

Women with intrahepatic cholestasis of pregnancy may also experience anorexia, fatigue, greasy stools, dark urine, and epigastric discomfort. Urinary tract infections are more common in women with ICP than unaffected pregnant women. Finally, a deficiency of vitamin K can develop in women who have a prolonged course of ICP.

Diagnosis

Intrahepatic cholestasis of pregnancy is diagnosed by blood tests showing elevated levels of bile acids and certain liver enzymes. The presence of itching without a primary rash also helps to confirm the diagnosis. A liver biopsy or ultrasound is rarely needed to establish the diagnosis.

Effect on Baby

The liver of a healthy fetus has a limited ability to remove bile acids from the blood. The fetus normally has to rely on the maternal liver to perform this function. Therefore, the elevated levels of maternal bile cause stress on the fetal liver. Intrahepatic cholestasis of pregnancy increases the risk to the baby of meconium staining during delivery, preterm delivery, and intrauterine death. Women with ICP should be monitored closely, and serious consideration should be given to inducing labor as soon as fetal lung maturity is confirmed.

Treatment

The itching of ICP can be treated with emollients, antihistamines, soothing baths, primrose oil, and anti-itching products such as Sarna. Medications that aid in bile secretion such as ursodeoxycholic acid (UDCA), cholestyramine, and S-adenosylmethionine have shown variable benefits in reducing itching and bile levels. High dose oral steroids may also be a possible treatment for ICP.  (+ info)

Can someone please tell me about the long term health effects of Intrahepatic Cholestasis of Pregnancy (ICP)?


I had a baby five months ago and I believe that I had undiagnosed (and consequently untreated) ICP at the time, which resulted in a premature delivery (at 35 weeks). My baby is healthy and doing well but my liver function tests have come back with a few highly elevated readings. Does anyone have any experience of this?
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Please see a physician to monitor the condition because the liver is a vital organ that handles all toxic substances which enters the body and can be destroyed too by these substances.  (+ info)

Does anyone Know about Obstetric Cholestasis?


I lost a baby girl in 2007, she was stillborn. Doctors didn't know why, and at the time I didn't have an autopsy done, and wish I had now. My husband and I are thinking of trying again, But also thinking of what could happen. I've looked online and found that this obstetric cholestasis is so close to what I was going through. Maybe the Doc didn't catch it in time :(
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I had Obstetric cholestasis. I had horrible itching that kept me up all night. one night when I couldn't sleep, I searched the internet and found Obstetric cholestasis and asked my doctor to be tested the following day. I had it. My doctor did a lot of extra testing due to it, but did not prescribe any medication. My babies (twins) were scheduled to be induced on Nov26th, which was 5 weeks early. My water broke 2 days before that.

other signs of obstetric cholestasis include very light colored stool.

I thought my babies were fine, but it turns out they both have autism. I always wonder if the cholestasis had something to do with the boys having autism.

good luck to you in your quest.  (+ info)

I just want to know if anyone else had cholestasis during there pregnancy. And if so were you and the baby ok.


Im 36 weeks and on meds for it im just very nervous.
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I had cholestasis too when I was pregnant with twins in the fall of 2002. I also had gestational diabetes and pre-eclampsia. It seemed like everything was ok when the twins were born, but when they were 2 yrs. old they were both diagnosed with autism. Since there is not a lot of information about either cholestasis or the causes autism, it is impossible to tell if they are connected. from what I understand, most babies born to mothers who have cholestasis are fine as long as they are born a few weeks early. Is your doctor going to induce labor early? Good luck to you.  (+ info)

I am 37 weeks pregnant and have just been diagnosed with obstetric cholestasis will they induce me early ?


the practice of delivering babies early from mothers who have this is currently under review as the complications which were previously considerd a risk they are no longer sure of . They did used to deliver babies at 37 weeks from mothers who had this now there are other treatments such vitamin k supplements , Ursodeoxycholic acid ( although some doctors midwifes may still induce early )you need to speak to your midwife or doctor about your concernes but you will be closely monitored now you have been diagnosed with this if you are not find out why !! hope this helps lou xx  (+ info)

what is obstetric cholestasis?


I am 15 weeks preg and getting loads of itching on my hands an feet and been told it could be that obstetric cholestasis
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  (+ info)

social security for cholestasis for my six month old infant on medication?


I'm not entirely sure what your question is, but if your asking what i think, it depends on how much you make  (+ info)

has anyone suffered from intrahepatic cholestasis of pregnancy or ICP?


what happened to you and your child, and how did they find out you had it?
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There is a good resource for ICP moms at www.itchymoms.com.

There are also some active Yahoo Groups where you can get more personalized advice and experiences.  (+ info)

did/does anyone have PUPPP, Pemphigoid gestationis, or Intrahepatic Cholestasis of Pregnancy?


if any one had any of these what were your symptoms? what did it look like? and what kind of tests did your doctor do to confirm it? also what was the treatment? and was there any risk to your baby?
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I had Cholestasis of Pregnancy. I just started itching really badly. Mostly on my palms and my feet, but I did itch other places. My doctor did a few liver enzyme tests and realized that those enzymes were elevated. They delivered my little girl almost a month early due to the possibility of stillbirth and other possible risks. Check out the web site below! Lots of helpful advice!  (+ info)

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