FAQ - Cholestasis, Extrahepatic
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Has anyone had or have Cholestasis during pregnancy and what was/is the outcome?


I've been itchy for about a week now but since last night developed big rashes all over my body and fear I might have that I'm going in to see my doctor today but wanted to know more about it from weman who actually have it or got it during pregnancy. Thank you so much for sharing....:)
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I've already "spoken" with you about my experience, but I'll try to go into a little more detail.

I actually "journaled" both of my pregnancies, so I know exactly when the itching started with my first. It started when I was about 7 weeks pregnant as a rash on my upper arms only. From there it spread across my chest, down my belly, and then down my legs. I actually scratched myself bloody at points.

My ob-gyn sent me to a dermatologist, who found nothing wrong with the standard blood tests (they did not do the needed tests for cholestasis). I was prescribed two different creams but neither helped. On the third trip in, they did a skin biopsy of one of the rashy bumps, and again found nothing. By that time I was about 6 months pregnant, and I looked like I had the plague or something. The itch kept me up at night even. I would wake up scratching with the sheets all bloody.

It did start to slack off a little when I was about 30 weeks, but then my daughter was born right at 32 weeks gestation. The itching immediately stopped after she was born, and a different doctor was the one that actually diagnosed the cholestasis postpartum. I also had hypertension, (often associated with cholestasis) and gestational diabetes with her.

I did not have any of the problems with my son that I had with my daughter, even though they say that if you have cholestasis with one you will have it with subsequent pregnancies. Go figure. I was much healthier with my second than I was with my first, so maybe that had something to do with it.  (+ info)

37 weeks, Intrahepatic Cholestasis of Pregnancy (now in control), What complications my baby can face?


Hi,

Doctor detected Intrahepatic Cholestasis of Pregnancy, on 32 weeks and now it is controlled by medicines. Now no more itching, but i am still on medicine.

I am 37 weeks pregnant and exited to see my babay soon. Please suggest me if i need to consider anything for my baby as i my pregnancy is Intrahepatic Cholestasis of Pregnancy.

Thank you
Regards
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Congrats for the expected baby. In part of my research of all the things that could happen while pregnant, I found this website that could be helpful for you.

http://www.itchymoms.com/  (+ info)

Anyone have a 2nd baby after losing one to cholestasis?


Also known as ICP or OC, severe itching during pregnancy due to build up of bile in the liver. Looking for a success story after our loss. Thanks
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I suggest you pick up the book "empty cradle, broken heart- surviving the death of your baby". It has a lot of information about ttc and subsequent pregnancies. It helped me a lot, although I didn't have your specific condition.  (+ info)

Did you have Cholestasis from pregnancy...What was your labor induction like?


I am 36 weeks pregnant now, and was diagnosed two weeks ago with cholestasis. They are inducing me in four days, and I was wondering if anyone else has had this experience. Did they monitor you constantly during the labor? Were you able to walk around or did they make you stay in bed the whole time? Is the pitocin as bad as everyone says? Any info welcome. Thanks
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was induced with my son and I actually didnt go into labor until they broke my water the next morning, after that i had an epidural and didn't get up to walk couldn't. The pitocin wasn't that bad as everyone is making it out to be at least for me it wasn't and if it gets bad you can get epidural. Once i got the epidural my body was able to relax and i was able to have more productive contractions to dilate the cervix and the labor went quicker so keep an open mind to that. there are pain medications you can have through the iv, but they make you really drowsy and drugged feeling and don't really take the pain away. Not sure if you can walk around after they start pitocin don't see why not but you should ask your doc all of these questions before you have this done so you will know what to expect. My cousin had cholestasis and she had a healthy baby girl a year ago she also wasn't dilating all day and finally they gave her an epidural she dilated to 10 cm within like an hour and then was able to get her baby out so it made her labor faster too. Everyone's labor is going to be diff and depends on your pain tolerance, so don't let people scare you with the horror stories and remember it is very temporary and will be over soon and you will have your baby thats the reward and what a great reward it is. good luck and congrats  (+ info)

does anyone know about Cholestasis of Pregnancy?


if so, has anyone been diagnosed? was it hard to get diagnosed/treated? did the treatment help? is the baby okay? did it cause any complications during delivery?
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I had cholestasis of pregnancy with my last pregnancy. I was extremely itchy and that is what tipped the doctor off. He sent me for blood tests asap, and they came back positive. I didnt show symptoms until I was 38 weeks pregnant. At 39 weeks pregnant I had a planned c section, so we just went along with that. I had no complications, the baby had no complications.
A couple of friends of mine had cholestasis as well. They learned about it earlier on then I did. They took medication and it did help to some degree but both ended up having their baby at the 37 week mark. Their babies were fantastically healthy when born.  (+ info)

Im 36 weeks 3 days pregnant and have cholestasis.?


I have been taking a lot of blood test lately for this cholestasis because it goes up and down. The blood results are like 15 so the doctor don't want to do anything about it, they said the highest is 40 and then they can induced me but because I am only 15(DONT REMEMBER THE NAME) which means its very low then they wouldn't do anything,I just have to check the baby movement everyday. Have anyone been thorough this?Are they doing the right thing?
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I haven't experienced this personally, but check out this website:

http://www.ocsupport.org.uk/

From reading the FAQ section there, it said that through monitoring, the risk to the baby is comparable to that of a normal pregnancy, and there are no known long-term effects to you or the baby. While there are treatments, there hasn't been the level of research on them to insure they are safer than just closely monitoring, so it sounds like they are doing the right thing. I'm sure it is scary with all the technical information and blood tests, but I suspect the best thing for you and your baby is to relax; you're almost to full term and you'll have the baby in your arms before you know it.  (+ info)

Does anyone know much about Cholestasis during pregnancy?


I developed a major itching last week over my entire body, my doctor prescribed Urso for me which has helped a little bit, I have heard that it is dangerous to the baby and can result in the baby being stillborn. I had to go to the hospital today for fetal monitoring and when they called my Ob/gyn to let him know that things were okay on the monitor and to see if he wanted me to come in again next week, my doctor told the nurse that if the medication is working then they will not induce me as he had previously told me. I will be 38 weeks pregnant on thursday and I am very worried about this condition, how can I convince my doctor that I want to be induced? Not only is the stress of worrying about this driving me crazy, so is the itching and lack of sleep its causing. Thank you.
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I'm sorry to hear about that! It must be dreadful!

I'm going to include the link to a pregnancy and parenting forum that I think you might find helpful. I know some other women in there have suffered through rashes etc, and they may have some tips on how to deal with them :)  (+ info)

What it is: Progressive Familial Intrahepatic Cholestasis?


... and what is the best treatment for it?
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From the Cincinnati Children's Hospital website:

"Progressive familial intrahepatic cholestasis (PFIC) is a rare inherited condition in which children are unable to drain bile from the liver even though the large bile ducts are open (called cholestasis).

This usually begins in infants less than six months of age and may get worse very quickly. However, some children initially show signs later, even as late as the teen years, and the condition progresses more slowly. Nearly all children with progressive familial intrahepatic cholestasis will require treatment before age 30.

In many cases, progressive familial intrahepatic cholestasis leads to cirrhosis (irreversible scarring of the liver) and liver failure within the first 10 years of life. A liver transplant may be necessary for survival.

Treatment:

Some patients may respond to medical therapy, although surgical treatment is usually necessary for survival.

Surgical treatment used in children with progressive familial intrahepatic cholestasis includes liver transplantation for cirrhosis and partial external biliary diversion (PEBD).

Liver Transplantation

Liver transplantation may be used if partial external biliary diversion is ineffective or if the patient has liver cirrhosis. It is the only effective treatment of high-GGT PFIC.

Most progressive familial intrahepatic cholestasis disorders progress to end-stage liver disease and require liver transplantation. Treatment focuses on minimizing growth failure and decreasing discomfort as the child awaits liver transplantation. Survival rates for liver transplantation to treat progressive familial intrahepatic cholestasis are excellent.

Partial External Biliary Diversion (PEBD)

Partial external biliary diversion may be used as the first choice of treatment for patients who have not yet developed cirrhosis. This treatment helps reduce the circulation of bile acids in the liver in order to reduce complications and prevent the need for early transplantation in many patients.

This surgical technique involves isolating a segment of intestine 10 cm long for use as a biliary conduit (a channel for the passage of bile) from the rest of the intestine. One end of the conduit is attached to the gallbladder and the other end is brought out to the skin to form a stoma (a surgically constructed opening to permit the passage of waste).

Partial external biliary diversion is used for patients who are unresponsive to all medical therapy, especially older, larger patients. This procedure may not be of help to young patients such as infants. Partial external biliary diversion may decrease the intensity of the itching and abnormally low levels of cholesterol in the blood."  (+ info)

Anyone been checked for cholestasis and?


Today i had to have blood drawn and be checked for this.I have to wait a bit for the results to come back though.My question is...

Anyone else had a severe itch too and had this done and it came back negative and just had somthing else?
If it comes back positive will i most likely be induced early?
Im 37 weeks....
The thought of having it scares the heck outta me.
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I was tested for Cholestasis a few weeks ago, and my doc was totally convinced that's what I had, judging by the SEVERE itching on the soles of my feet. I ended up in labor and delivery for something totally unrelated, and the nurse checked my labs, and said everything looked fine. I stopped taking the meds for it and now the itching is back! I'm going to talk to my doc about it on Fri, but sometimes it takes a while for it to show up on a lab. Cholestasis is usually managable, just be glad your doc checked for it, since it can be fatal to the baby if left untreated. I still don't know why I'm so itchy... maybe it's just one of those things! GL!!  (+ info)

I have Cholestasis of Pregnancy Please help?


I have been recently diagnosed with this, and I was wondering? Where you induced early if so how early, cause my doctor said that he wants to monitor me 2 times a week with a non stress test and go from there. He hasn't really said how early I will be induced but he did say that it will happen. I also have Pregnancy induced Hypertension, which is also a factor of getting induced early....Please give me your stories...
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I have NST's done 2 times a week, it is done to monitor the baby and make sure they are not in distress. It also monitors contractionsif your having any. If they see the baby is in distress they will induce. The dr will try to go as long as possible to avoid complications and problems with the baby.  (+ info)

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