Cases reported "Wound Infection"

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1/9. Primary cutaneous mucormycosis in a trauma patient.

    We report a rare case of primary cutaneous mucormycosis caused by rhizopus oryzae that occurred in an immunocompetent trauma patient. The patient had encrusted erythematous plaques with pustules on the left shin, which had been abraded in a traffic accident. Histologic examination revealed widespread granulomatous inflammation and characteristic broad, non-septate hyphae with right-angle branching in the dermis. The infection was cured with intravenous amphotericin b therapy.
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ranking = 1
keywords = mucormycosis
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2/9. Craniofacial mucormycosis following assault: an unusual presentation of an unusual disease.

    A case of craniofacial mucormycosis following assault is discussed. A female diabetic developed peri-orbital cellulitis adjacent to a scalp wound which progressed to a necrotizing fasciitis. This did not respond to treatment. Subsequently the patient developed a hemiparesis, with CT imaging showing peri-orbital and paranasal sinus inflammatory changes, evidence of cavernous sinus invasion and development of a middle cerebral artery territory infarction. The patient died shortly afterwards. The imaging findings and their relationship to the pathological spread of mucor infection are discussed.
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ranking = 1
keywords = mucormycosis
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3/9. Multifocal cutaneous mucormycosis complicating polymicrobial wound infections in a tsunami survivor from sri lanka.

    A man injured in the tsunami of Dec 26, 2004, returned to Sydney for management of his soft-tissue injuries. Despite broad-spectrum antibiotics, surgical wound debridement, and vigilant wound care, his condition worsened. Muscle and fat necrosis developed in a previously debrided thigh wound, and necrotising lesions arose from previous abrasions. Histological analysis showed mucormycosis in three non-contiguous sites, and Apophysomyces elegans was isolated from excised wound tissue. Wound infections, both bacterial and fungal, will undoubtedly add to the morbidity and mortality already recorded in tsunami-affected areas. Other cases [correction] of cutaneous mucormycosis might develop in survivors, but this disease can be difficult to diagnose and even harder to treat, particularly in those remaining in affected regions.
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ranking = 1.2
keywords = mucormycosis
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4/9. Post-traumatic cutaneous mucormycosis in diabetes mellitus. Short-term antifungal therapy.

    mucormycosis is infrequently encountered in the pediatric population in any of its forms (nasopharyngeal, disseminated, pulmonary, or cutaneous) and generally is associated with the immunocompromised host. We present an adolescent with poorly controlled diabetes mellitus who developed a progressive skin lesion 3 weeks after a motor vehicle accident. rhizopus species was isolated from the lesion, and the biopsy revealed a fungal vasculopathy. Control of her diabetes, aggressive surgical intervention and a 10-day course of antifungal therapy (amphotericin b) resulted in a favorable outcome. This article illustrates the importance of considering cutaneous fungal infections, especially those in the class zygomycetes, in the diabetic patient with unusual, severe or persistent skin lesions. Early recognition is essential in order to avoid morbidity and mortality from this unusual opportunistic infection.
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ranking = 0.8
keywords = mucormycosis
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5/9. Wound zygomycosis (mucormycosis) in otherwise healthy adults.

    Two previously healthy men sustained trauma that caused extensive soft tissue damage together with soil contamination. Within three days, rapidly advancing necrosis was observed at the wound margins. Histologic examination revealed the presence of non-septate branching hyphae characteristic of mucorales within tissues and in the lumen of blood vessels. In one case, the disease was unrecognized until widespread dissemination had taken place, and the patient died; in the other, a cure resulted from aggressive medical and surgical management. Infections due to mucorales generally occur in immune-compromised hosts. In cases of extensive trauma, inoculation of devitalized tissues with soil may initiate infection by zygomycetes, even in persons whose immunologic status appears to be normal.
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ranking = 0.8
keywords = mucormycosis
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6/9. Injury from silage wagon accident complicated by mucormycosis.

    Infection due to farm machinery injuries may be caused by microorganisms found in soil or decaying vegetable material. A case of injury due to entrapment of a young boy in a silage wagon is reported here. His injuries were complicated by infection with aspergillus species, absidia species, rhizopus species (the latter two are members of the mucorales order), and pseudomonas maltophilia. Successful treatment of his infection followed aggressive surgical debridement of the anterior abdominal wall, amphotericin b, hyperbaric oxygen therapy, and surgical closure utilizing delayed placement of split-thickness skin grafts.
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ranking = 0.8
keywords = mucormycosis
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7/9. Pleural mucormycosis (zygomycosis).

    A biliary drainage catheter that traversed the right pleural space was associated with unilateral pleural infection by an unidentified zygomycete that caused pleural mucormycosis. The fungal infection was confined to the pleura and immediately subjacent lung. We interpreted these findings as a fungal wound infection that unfortunately involved a major body cavity.
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ranking = 1
keywords = mucormycosis
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8/9. Arterial occlusion and progressive gangrene caused by mucormycosis in a patient with burns.

    Ischemic necrosis of the upper extremities caused by invasive mucormycosis developed in a patient with soil contamination of severe burn wounds. An arteriogram of the arm showed complete obstruction of blood flow in the forearm. Histologic specimens showed nonseptate branching hyphae obliterating the arterial lumens. Cutaneous mucormycosis affects patients who are immunocompromised, including victims of multiple trauma and burns. This case represents a previously undescribed clinical presentation in a patient with major burns. Because of its lethal nature, mucormycosis in a patient with burns must be treated with aggressive surgical debridement, including amputation, and with parentral amphotericin b at the earliest sign of cutaneous presence.
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ranking = 1.4
keywords = mucormycosis
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9/9. Successful cure of an extensive burn injury complicated with mucor wound sepsis.

    mucormycosis is an opportunistic infection occurring in the severely immunocompromised patient. A case of mucormycosis occurring in a patient who sustained an 85 per cent TBSA burn injury is reported. diagnosis and management is reported in the paper.
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ranking = 0.2
keywords = mucormycosis
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