Cases reported "Uterine Cervical Diseases"

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1/12. ceroid granuloma of the uterine cervix.

    A case of ceroid granuloma of the uterine cervix in a 58-year-old woman is presented, the fourth such case in the literature. It was an incidental finding during a routine pelvic examination and appeared as an exophytic brownish lesion on the anterior wall of the uterine cervix. On histological examination it consisted of sheets of ceroid-rich histiocytes within the superficial cervical stroma. There was no obvious cause for the lesion. ceroid granulomas of the female genital tract may be related to endometriosis, but the rarity of the cases precludes definite conclusions about the etiology and pathogenesis of this lesion.
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2/12. ceroid granuloma of the uterine cervix.

    An excision biopsy was taken from a 59-year-old woman with a small dark-brown lesion on the anterior lip of the cervix. The histology revealed an ulcerated surface epithelium with a band-like infiltrate of pigment containing macrophages in the subepithelial zone. Histochemical examination of the specimen revealed that the pigment was ceroid. This is, to the best of our knowledge, the first case report of ceroid granuloma of the uterine cervix.
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keywords = granuloma
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3/12. granuloma inguinale of the cervix: a carcinoma look-alike.

    granuloma inguinale of the cervix presents as a proliferative growth and may mimic carcinoma. Over a 3 year period 18 patients with cervical granuloma inguinale were detected. Nine (50%) had a clinical diagnosis of carcinoma of the cervix on admission, five of whom had extensive investigations to exclude a malignancy. In communities where these two conditions are commonly seen it is recommended that granuloma inguinale be considered in young women with granulomatous lesions of the cervix, so as to avoid extensive and financially costly investigations, and unnecessary psychological stress for patients.
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4/12. Cytologic detection of cervical granuloma inguinale.

    Two cases of granuloma inguinale detected cytologically on routine Papanicolaou-stained cervical smears are presented; the cytologic and histologic features are described in detail, and the electron microscopic appearances are shown. The suitability of the Papanicolaou stain in the detection of granuloma inguinale is discussed, with emphasis on possible differential diagnoses to be considered. It is concluded that a definitive diagnosis of granuloma inguinale can be made on routine Papanicolaou-stained smears showing the following spectrum of changes: intact capillaries indicative of epithelial and stromal ulceration; a marked inflammatory cell infiltrate consisting predominantly of neutrophils; epithelioid histiocytes representing granuloma formation; and Donovan bodies located in characteristic single or multiple intracytoplasmic vacuoles within large histiocytes. Recognition of this cytologic picture may enable early diagnosis, even in nonendemic areas, of a potentially disfiguring venereal disease.
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5/12. Malakoplakia of the female genital tract.

    A rare case of malakoplakia of the uterine cervix and the pelvis occurring in an elderly woman who also had xanthogranulomatous pyelonephritis is described and compared with the 15 reported cases of malakoplakia of the female genital tract.
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keywords = granuloma
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6/12. Adverse effects of pregnancy on multifocal eosinophilic granuloma.

    An unusual case of a patient diagnosed as having the histiocytic proliferative disorder characterized by the lesion eosinophilic granuloma (histiocytosis X) is presented. Fifteen-year follow-up revealed a progression from a solitary eosinophilic granuloma of the bone to multifocal involvement of many body structures including the vulva, vagina, and cervix. This progression occurred after nine asymptomatic years and was temporally related to the patient's first pregnancy. After successful treatment and remission, rapid appearance and growth of observable genital lesions were noted during a second pregnancy. pregnancy termination in the first trimester was advised due to signs of dissemination and local symptoms.
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7/12. Donovanosis affecting cervix, uterus, and adnexae.

    Donovanosis (granuloma inguinale), a disease often related to sexual contact, has been a clinical problem in papua new guinea for more than 9 decades. It is a common cause of anogenital lesions in females in this country. Lesions on the cervix or vaginal vault, and extension of the disease process from the external genitalia to the uterus, tubes and ovaries, are thought to be rare. In this study an attempt was made to discover the frequency of involvement of cervix, uterus and adnexae, with or without external genital involvement, by retrospectively analyzing the histological and clinical records of patients with anogenital donovanosis for a period of 8 years (1975-1982). In 35 of 351 patients (10%), donovanosis involved the cervix. The clinical profile of these cases, certain unusual features in a few cases, and the pathological findings are discussed.
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keywords = granuloma
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8/12. Necrobiotic granulomas of the uterine cervix. A probable postoperative reaction.

    Three cases of necrobiotic granulomas of the uterine cervix occurring in patients with a history of previous cervical surgery are described. This distinctive lesion histologically resembles a rheumatoid nodule but is not associated with infection or connective tissue disease. The clinicopathologic features of these cases are virtually identical to analogous postoperative lesions that have been described in the prostate. Such necrobiotic granulomas seem to be a result of prior surgery and should not be confused with other more portentous granulomatous diseases.
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keywords = granuloma
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9/12. malacoplakia of the uterine cervix: report of two cases.

    Two cases of malacoplakia involving the uterine cervix are reported. Lesions of the genital tract caused by this uncommon granulomatous reaction may suggest malignancy clinically and may present with vaginal bleeding. Cytologic findings in cervical smears from both patients included inflammation and abundant histiocytes. The characteristic finding is the Michaelis-Gutmann body, which can be identified in cervical smears, especially with the use of PAS or von Kossa stain. Gram-negative bacilli may be cultured from the tissue or identified on Gram's stain. Antibiotics are probably effective in eradication, as is surgical excision.
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ranking = 0.16666666666667
keywords = granuloma
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10/12. Pinworm granuloma of cervix uteri--incidental observation following IUD use and cone biopsy.

    A pinworm granuloma of cervix uteri was found incidentally in a hysterectomy specimen following cone biopsy for severe epithelial atypia. This lesion was regarded as too recently formed to be related to prior IUD use. The granuloma was apparently asymptomatic, as were 24 of 34 such lesions cited as involving uterus, adnexa or pelvic peritoneum or some combination of these sites. The only previous instance to be found of apparently deep cervical invasion by pinworms was associated with grossly evident carcinoma; the intact cervix has not yet been reported as subject to pinworm invasion.
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