1/5. Successful use of fluconazole for treatment of urinary tract fungal infections.Two cases are reported that demonstrate significant activity of the new antifungal agent, fluconazole, in treating urinary tract fungal infections. One patient was severely immunocompromised with the underlying complication of renal failure and the other presented with a much simpler case of candidal cystitis that responded quickly despite unfavorable in vitro susceptibility testing.- - - - - - - - - - ranking = 1keywords = candida (Clic here for more details about this article) |
2/5. Extracorporeal shock wave lithotripsy of a kidney stone complicated with Candida albicans septicaemia and endophthalmitis. Case report.Following a routine extracorporeal shock wave lithotripsy of a kidney stone, candida septicaemia and eight days later candida endophthalmitis developed.- - - - - - - - - - ranking = 2keywords = candida (Clic here for more details about this article) |
3/5. Fungal bezoar and bladder rupture secondary to candida tropicalis.Candidal urinary tract infections typically occur in a host with compromised immune function. Although usually associated with aerobic bacterial infections, emphysematous cystitis occasionally complicates fungal infections of the lower urinary tract, especially in diabetics. Another uncommon occurrence is formation of a "fungus ball" leading to obstructive uropathy. We present a case of bladder rupture in a patient with emphysematous cystitis and obstructing fungal bezoar caused by candida tropicalis. Various factors predispose to fungal urinary tract infection, including diabetes mellitus, neurogenic bladder, antibiotic usage, and the presence of an indwelling urinary catheter.- - - - - - - - - - ranking = 4keywords = candida (Clic here for more details about this article) |
4/5. Evaluation of plasma (1-->3)-beta-D-glucan measurement by the kinetic turbidimetric limulus test, for the clinical diagnosis of mycotic infections.The present multicentre clinical study was conducted to assess the clinical utility of a new diagnostic method for deep mycosis in which (1-->3)-beta-D-glucan, a fungal cell wall component existing in plasma, was quantitatively measured by the kinetic turbidimetric limulus test (WB003). plasma (1-->3)-beta-D-glucan concentrations were 0.57 /- 0.10 microgram/l in 92 healthy subjects and 0.62 /- 0.32 microgram/l in 26 patients with non-mycotic diseases (disease control group). In comparison with these healthy subjects and patients with non-mycotic diseases, patients with mycosis had significantly higher plasma (1-->3)-beta-D-glucan concentrations: 19.63 /- 73.28 micrograms/l in 12 patients with candidaemia, 11.28 /- 21.42 micrograms/l in 7 patients with urinary Candida infection, 4.84 /- 12.71 micrograms/l in 5 patients with pulmonary candidiasis, and 12.21 /- 31.31 micrograms/l in 4 patients with invasive pulmonary aspergillosis. On the statistical analysis of these data, a cut-off value was set at 1.0 microgram/l. Using this cut-off value, 3 patients with pulmonary cryptococcosis and 4 patients (4/6) with pulmonary aspergilloma were all negative with low plasma (1-->3-beta-D-glucan levels. The test WB003 provided equivalent or higher efficiency of diagnosis of candidiasis and aspergillosis, in comparison with commercially available antigen detection kits, demonstrating its utility as a diagnostic reagent. It may also be useful in assessing therapeutic effectiveness when used periodically after treatment.- - - - - - - - - - ranking = 1keywords = candida (Clic here for more details about this article) |
5/5. Treatment of candidal urinary tract infection with nifuratel.Three patients with candidal urinary tract infections were successfully treated with oral nifuratel, a nitrofuran antimicrobial agent active against yeast and trichomonas as well as urinary bacterial pathogens. The recommended dose is 400 mg thrice daily for a week. No side effects that could be attributed to the treatment were noted. Minimum ibhibitory concentration determinations for nifuratel against Candida strains of five species showed that 48 out of 59 organisms were inhibited by 50 mg/1 or less, the three strains of Candida species eliminated from our treated patients having MICs of nifuratel in the range of 10-50 mg/1.- - - - - - - - - - ranking = 5keywords = candida (Clic here for more details about this article) |