1/4. Subfoveal nodule in Coats' disease.An atypical presentation of Coats' disease is reported with a prominent subfoveal nodule with peripheral retinal exudates. A 6-year old boy presented with 6/120 vision in the left eye associated with an elevated 1 mm subfoveal, circular lesion with peripheral exudates. The fluorescein angiogram showed peripheral retinal telangiectasias with leakage consistent with Coats' disease. The prominent subfoveal nodule is an uncommon initial presentation of Coats' disease and physicians should be aware of this atypical finding.- - - - - - - - - - ranking = 1keywords = physician (Clic here for more details about this article) |
2/4. Rendu-Osler-Weber-like telangiectasia associated with primary biliary cirrhosis.An otherwise asymptomatic woman presented with the recent onset of telangiectasias of the lips and fingertips, and without a family history of similar lesions. Results of laboratory tests included elevated liver function, positive antimitochondrial antibodies, and microscopic findings compatible with the diagnosis of primary biliary cirrhosis (PBC). New lesions of skin and mucous membranes resembling manifestations of the Rendu-Osler-Weber syndrome should prompt the physician to rule out PBC and associated autoimmune diseases.- - - - - - - - - - ranking = 1keywords = physician (Clic here for more details about this article) |
3/4. Superior vena caval syndrome.The two cases of the superior vena caval syndrome described illustrate the problem of making a diagnosis and of determining the etiology of this syndrome. The cutaneous manifestations were typical of the syndrome and included the sudden onset of facial and upper extremity edema, erythema, and telangiectasia. The causes of the syndrome cannot be recognized from the clinical presentation. In one of our cases, the cause was only determined at autopsy and proved to be an unusual benign cause, idiopathic thrombosis, masquerading as a malignant tumor; the other case was caused by an actual malignancy. The manifestations of the syndrome should alert the physician to determine its cause in order that appropriate therapy may be instituted as rapidly as possible.- - - - - - - - - - ranking = 1keywords = physician (Clic here for more details about this article) |
4/4. An unusual presentation of telangiectatic osteosarcoma.Telangiectatic osteosarcoma (TOS) is a rare subtype of osteosarcoma that accounts for approximately 2% of all osteosarcomas. Presented is a case of a sacral mass that was originally thought to be a chordoma and was treated surgically but on pathologic examination was diagnosed as a TOS. A review of the literature on other sacral lesions is provided. The intention for presenting this case is twofold: to make physicians aware of the differential diagnoses of sacral lesions and to report an unusual presentation of this rare tumor.- - - - - - - - - - ranking = 1keywords = physician (Clic here for more details about this article) |