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1/6. Pigmented villonodular synovitis: keys to early diagnosis.

    Pigmented villonodular synovitis is a synovial proliferative disorder that remains a diagnostic difficulty. Many clues in the history, physical examination, and radiographic studies can aid in the diagnosis. A patient in the third or fourth decade of life often will present with vague monoarticular complaints. Symptoms include intermittent, extreme deep pain localized to the hip, occasionally relieved by position. Decreased active and passive range of motion may be found. Small erosions in the head of the femur and acetabulum may occur early in the course of the disease. magnetic resonance imaging is the imaging modality of choice and will show the characteristic findings of a joint effusion, synovial proliferation, and bulging of the hip. The synovial lining has a low signal on T1- and T2-weighted images, secondary to hemosiderin deposition. Pigmented villonodular synovitis should be included in the differential diagnosis of young patients with unexplained hip pain.
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2/6. tuberculosis of the hip as the presenting sign of hiv and simulating pigmented villonodular synovitis.

    A 36-year old man, with no prior known exposure to human immunodeficiency virus (hiv) or tuberculosis, presented with monoarticular pain and a decreased range of motion in his left hip. radiography and magnetic resonance imaging revealed bony erosive lesions, juxta-articular cysts, a large effusion, and juxta-articular edema. The initial clinical and radiographic diagnosis was pigmented villonodular synovitis (PVNS) of the left hip. However, what was initially felt to be a chronic proliferative inflammatory process was later determined to be tuberculous arthritis. This case emphasizes the importance of including tuberculous arthritis in the differential diagnosis of patients with monoarticular destructive joint disease radiologically suggestive of PVNS.
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3/6. Intra-articular hemangioma of the knee as a cause of knee pain.

    We report the case of a young patient with knee pain, limited range of motion, and swelling due to an intra-articular hemangioma. Clinically, the symptoms and findings were similar to those of a meniscal lesion. The diagnosis of an intra-articular tumor was made using magnetic resonance imaging. The tumor was excised, and the definitive diagnosis was made histologically. After tumor excision, the patient was pain free.
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4/6. Diffuse pigmented villonodular synovitis of the shoulder. A case report & review of literature.

    The combination of a diffuse pigmented villonodular synovitis and a rotator cuff tear of the shoulder in a 64-year-old man is described. The patient was treated by complete synovectomy, open repair of the rotator cuff tear and a Neer acromioplasty. Six months after this surgical treatment the patient was free of pain, and clinical examination revealed an almost normal range of motion.
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5/6. The use of MRI to assist in diagnosis of pigmented villonodular synovitis of the knee joint.

    Pigmented villonodular synovitis (PVNS) of the knee joint remains a difficult and elusive entity to define and characterize. This entity most often appears in the young adult knee with nonspecific clinical features, including a painful range of motion and perhaps a sensation of locking. Detection and diagnosis of this localized soft-tissue mass are difficult because plain roentgenograms may be totally within normal limits. The case of a 21-year-old woman illustrates the use of magnetic resonance imaging (MRI) as an effective technique to define and characterize PVNS. Advantages of MRI include high-resolution/high-contrast multiplanar sections that depict bone, marrow, ligaments and tendons, fat, menisci, and articular cartilage in one image. In addition, MRI is noninvasive and requires no ionized radiation. MRI is an excellent clinical tool for the evaluation of intraarticular tumors of the knee joint.
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6/6. Localized pigmented villonodular synovitis: a rare cause of locking of the knee.

    A 34-year-old woman presented with a history of recurrent episodes of knee locking and swelling. arthroscopy revealed characteristic brown colored pedunculated lesions in the intercondylar notch region. These were clearly causing interference to joint motion. The lesions were resected arthroscopically with prompt resolution in symptoms. Histological examination confirmed pigmented villonodular synovitis.
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