Cases reported "Sporotrichosis"

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1/101. erysipeloid sporotrichosis in a woman with Cushing's disease.

    A woman presented with a swollen red leg of 2 weeks' duration. culture of the skin biopsy specimen confirmed this to be an infection caused by sporothrix schenckii. Systemic evaluation led to the diagnosis of Cushing's disease and explained the unusual morphology. Treatment-related complications are also discussed.
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2/101. sporothrix meningitis.

    sporothrix schenckii is a fungus commonly found in soil and on plants, wood splinters, rosebush thorns, and decaying vegetation. It is also carried by some wild and domestic animals and rodents. When this organism penetrates the skin of individuals handling contaminated substances, the cutaneous manifestation may be lymphangitic or fixed. The treatment of choice for the cutaneous form of the disease (sporotrichosis) is potassium iodide. If iodides are contraindicated or not tolerated, itraconazole may be used. sporotrichosis can persist for years if unrecognized and can progress to systemic forms, including osteoarticular, pulmonary (may occur when the organism is inhaled), and meningeal involvement. Systemic forms can be life-threatening and very difficult to treat. Primary care providers must be familiar with this disorder and its presentation because it is easily mistaken for a bacterial infection and inappropriately treated.
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3/101. Lymphocutaneous sporotrichosis: a case report and unconventional source of infection.

    A 32-year-old white man had a 5-month history of a progressively worsening rash on the dorsal aspect of his left foot. He stated that he engaged in self-tattooing of the left foot prior to the onset of the rash. Further questioning revealed that he had mowed the lawn wearing only sandals on the same day that he had tattooed his foot. The rash was diagnosed as lymphocutaneous sporotrichosis based on clinical appearance, biopsy examination, and fungal culture. Clearing of the lesions was documented following 4 months of therapy with itraconazole. The remaining granulomatous lesions were flattened with intralesional corticosteroid injections.
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4/101. Cutaneous New World leishmaniasis-sporotrichosis coinfection: report of 3 cases.

    Three cases of coinfection with Leishmania and sporothrix spp in the same lesion are described. The patients had ulcers with erythematous borders and regional lymphadenopathy. The diagnosis of leishmaniasis was accomplished by direct visualization of the amastigotes or culture of the promastigotes, or both. The diagnosis of sporotrichosis was proved in two cases by culture of sporothrix schenckii and by the histopathologic features in one case. All patients had a positive sporotrichin test. Two patients responded successfully to oral potassium iodide. One patient received oral itraconazole 100 mg/day because of intolerance to iodides and was cured. To our knowledge coinfection with Leishmania and sporothrix spp has not been reported. The use of empirical treatments for leishmaniasis such as poultices or puncturing of the lesion with thorns or woods splinters might introduce sporothrix and explain the coinfection.
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5/101. mycobacterium marinum with associated bursitis.

    BACKGROUND: mycobacterium marinum infections have been reported for over 50 years, mostly in association with trauma in the setting of water exposure. OBJECTIVE: The differential diagnosis for nodules in a sporotrichoid distribution with simultaneous bursitis is discussed. mycobacterium marinum treatment regimens for skin and joint involvement are reviewed. methods: mycobacterium marinum was identified by skin tissue culture with Lowenstein-Jensen medium at 32 degrees C. Histopathologic findings support mycobacterial infection. RESULTS: bursitis and nodules resolved in the first 2 months of a 6-month course of minocycline treatment. CONCLUSION: bursitis is an extremely rare but significant complication of M. marinum.
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6/101. Sporotrichoid dermatosis caused by Mycobacterium abscessus from a public bath.

    Infections caused by nontuberculous mycobacteria (NTM) are usually associated with immunocompromised states. More recently, however, NTM infections are being diagnosed with greater frequency in patients lacking traditional risk factors. However, cutaneous infection with rapidly growing mycobacteria is uncommon, and diagnosis may be difficult. Herein we present a case of sporotrichoid dermatosis on both forearms caused by Mycobacterium abscessus in a 34-year-old female (case 1). Mycobacterium abscesus was identified by culture as a colorless colony with rapid growth and by comparative sequence analysis of the rpoB gene. The patient was suspected to have been infected in a public bath in which she worked, it was located in a famous hot spring area in korea. The condition was first noticed after she had been working in the bath for two years and after another employee (case 2) suffered similar lesions which had responded to treatment. The patient's skin lesions were successfully treated with anti-tuberculous drugs for six months.
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7/101. Sporotrichoid presentations in leprosy.

    Two adult patients of leprosy, one woman and one man, presented with a clinical picture simulating sporotrichosis. The skin and regional nerve trunk was affected in one, and in the other the disease was confined to the nerve. Both had features of an upgrading reaction following anti-leprosy therapy; this was seen as erosion and scarring of the plaque, and acute onset of abscesses along the easily palpable and thickened nerve that ruptured through the skin. The diagnosis was supported by histopathology. In the light of other infections that give rise to a sporotrichoid pattern of infection it is concluded that leprosy should also be included in this category so that early diagnosis and use of corticosteroids can be implemented quickly to prevent nerve destruction.
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8/101. Bursal sporotrichosis: case report and review.

    We describe a patient whose prepatellar bursa was infected with sporothrix schenckii. The infection persisted despite itraconazole therapy and cure was achieved only after surgical excision of the bursa. A review of treatments for bursal sporotrichosis is presented.
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9/101. Oral manifestation of sporotrichosis in AIDS patients.

    A wide spectrum of oral lesions has been associated with human immunodeficiency viral infection (hiv), or AIDS. This report describes the case of an hiv-infected patient who developed a case of disseminated sporotrichosis whose first clinical sign was the presence of orofacial lesions. A histopathological study of this patient's biopsy specimens taken from the oropharyngeal lesions revealed a number of rounded and/or oval free-spore forms of sporothrix schenkii, the identification of which was corroborated by culturing skin lesion exudate on Sabouraud's glucose agar. To the best of our knowledge to date, this is the first time a case of the oral manifestation of sporotrichosis in association with hiv infection has been described in the dental literature.
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10/101. Zoonotic sporotrichosis. Transmission to humans by infected domestic cat scratching: report of four cases in Sao Paulo, brazil.

    BACKGROUND: sporotrichosis is a chronic, granulomatous, deep mycosis caused by the dimorphic fungus sporothrix schenckii that usually results in indolent cutaneous lesions. OBJECTIVE: To describe four cases of human sporotrichosis transmitted by domestic cats in south-eastern brazil. methods: Confirmation of the diagnosis was performed by histopathology, culture, and/or inoculation of hamsters. RESULTS: In all cases, the clinical findings in both cat and human groups were highly distinctive of the disease. In all human cases, there was a previous history of cat scratching before the development of lymphocutaneous lesions. Histopathology of the human lesions demonstrated the classical granulomatous and exudative pattern with scarce or absent fungal elements. Conversely, in cats, the cutaneous lesions were multiple, extensive, necrotic, exudative, and ulcerated. Histopathology revealed a widespread histiocytic reaction with a large number of fungal organisms. Disseminated lymphatic and visceral mycotic infection was observed in two necropsied cats. CONCLUSIONS: Domestic cats may be an important carrier of agents of sporotrichosis to humans.
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