Cases reported "Siderosis"

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1/5. Fluorescein angiographic findings in ocular siderosis.

    PURPOSE: To report a case of siderosis from a retained intraocular iron foreign body manifesting localized retinal capillary nonperfusion documented by fluorescein angiography. methods: Case Report. In a 35-year-old man with decreased vision in the left eye, studies included fundus photography, fluorescein angiography, visual field testing, and electrophysiology. Surgical foreign body extraction and histopathologic examination were performed. RESULTS: Preoperatively, in the left eye, humphrey visual fields and electrophysiology testing revealed marked depression. fluorescein angiography demonstrated nasal capillary nonperfusion with occlusion of the second- and third-order arterioles extending along a gradient from the foreign body. Microscopic examination of the lens capsule confirmed the diagnosis of siderosis secondary to a retained iron foreign body. CONCLUSION: Extensive capillary nonperfusion may be associated with a retained iron intraocular foreign body, as documented by fluorescein angiography.
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2/5. A long term follow up of ocular siderosis: quantitative assessment of the electroretinogram.

    siderosis oculi is a severe sequel of retained, iron made, intraocular foreign body. iron atoms or ions, dissolved from the foreign body, may diffuse to the retina and produce irreversible cellular damage. Therefore, early extraction of an iron foreign body is recommended. When the risks of surgical intervention outweigh the danger of siderosis, the patient is periodically examined in order to detect the initial signs of siderosis. The most commonly used test for quantitative and objective assessment of retinal function is the electroretinogram (ERG). We report here a long term ERG follow-up (about 8 years) of a patient suffering from a unilateral iron intraocular foreign body. The development of siderosis was detected by any of the ERG responses; cone-dominated, rod-dominated or mixed cone-rod responses. However, the degree of the assessed damage varied and strongly depended upon the flash intensity used to elicit the ERG response and upon the ERG wave chosen to assess retinal function. The relationship between the ERG b- and a-waves showed a profound deterioration reflecting a reduction in signal transmission from the photoreceptors to the inner nuclear layer. These findings suggested that iron toxicity produced more damage to the inner retina than to the outer retina.
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3/5. Management of siderosis bulbi due to a retained iron-containing intraocular foreign body.

    The authors report their experience in managing 14 cases of siderosis bulbi secondary to a retained iron-containing intraocular foreign body (IOFB). The IOFB was removed in 12 of the 14 eyes. The IOFB was removed with a sclerotomy and external magnet (5 eyes), a pars plana vitrectomy (PPV) and intraocular forceps (5 eyes), a PPV and intraocular magnet (1 eye), and a PPV with aspiration using the suction mode of the vitrectomy instrument (1 eye). A siderotic cataract developed in 11 eyes and cataract extraction resulted in postoperative visual acuity ranging from 20/15 to 20/40. The most recent siderotic cataracts have been managed with cataract extraction and posterior chamber intraocular lens (PC IOL) implantation. No patient in this series experienced visual deterioration after receiving medical attention. The current management of siderosis bulbi is discussed.
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4/5. siderosis bulbi induced by intraocular lens implantation.

    A 43-year-old man had a silent intraocular foreign body at the ciliary body that was composed of iron. siderosis bulbi was observed after an extracapsular cataract extraction with intraocular lens implantation was performed. The mechanical forces applied during the surgery might have been responsible for liberating the ferrous ion into the globe.
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5/5. siderosis from a retained intraocular stone.

    A penetrating intraocular stone caused a retinal detachment that was repaired successfully. The patient returned 18 months later with siderosis bulbi. The patient was followed by serial neurosensory tests for the next three years. The electro-oculogram (EOG) showed the greatest abnormality, while the electroretinogram (ERG) and dark adaptation, although initially affected, showed no further deterioration. Surgical procedures on this eye included linear extraction of the siderotic lens, anterior vitrectomy, and irrigation of a hyphema. Fluorescein angiogram revealed a siderotic deposit on the retina. Progressive visual field loss prompted removal of the stone foreign body by an eye-wall resection technique. Five years later vision was 20/30. While dark adaptation, EOG, and ERG remained stable, the visual fields showed progressive constriction. Fluorescein angiogram revealed pigment epithelial defects, cystoid macular edema, reduced peripheral circulation, and progressive clearing of the retinal iron deposits.
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