1/2. A case of peritonitis caused by rhizopus microsporus.We report a case of a 62-year-old female patient who developed peritonitis after receiving a renal transplant. candida glabrata was detected and treated with voriconazole. As the patient did not improve under therapy, laparotomy was performed. Mould-like plaques were found on the peritoneum. Using culture as well as pan-fungal polymerase chain reaction (PCR) followed by dna microarray hybridisation of the amplicon, the causative agent was identified as rhizopus microsporus. Despite aggressive surgical treatment, intravenous therapy with amphotericin b and topical administration of Lavasept (polyhexamethylenbiguanide), the patient died.- - - - - - - - - - ranking = 1keywords = administration (Clic here for more details about this article) |
2/2. Applying the Growth Failure in CKD consensus Conference: evaluation and treatment algorithm in children with chronic kidney disease.Growth failure is a common and significant clinical problem for children with chronic kidney disease (CKD), particularly those with chronic renal insufficiency (CRI). Children with CRI (typically defined by a glomerular filtration rate [GFR] <75 mL/min/1.73 m2) who have growth impairment exhibit a variety of medical and psychological problems in addition to increased mortality. Growth failure in children with CKD is usually multifactorial in etiology, including abnormalities in the growth hormone (GH)-insulin-like growth factor (IGF)-I axis and a variety of nutritional and metabolic concerns characteristic of CKD. Proper management of these factors contributes to better growth in affected children. Although the safety and efficacy of recombinant human GH (rhGH) therapy in promoting growth in children with CKD are well established, recent data indicate that the use of rhGH administration in children with CKD and growth failure remains low. Recently, guidelines were developed by the consensus Conference for Evaluation and Treatment of Growth Failure in Children with CKD. This paper focuses on the application of these guidelines to children with CKD.- - - - - - - - - - ranking = 1keywords = administration (Clic here for more details about this article) |