1/12. seminoma metastatic to the prostate resulting in a rectovesical fistula.We report an unusual presentation of metastatic seminoma within the prostate gland. Histological diagnosis was obtained using trans-rectal ultrasound guided prostatic biopsy. The patient developed a rectovesical fistula after ten weeks of chemotherapy, which healed following a complete radiological response to treatment- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
2/12. Implantation of rectal cancer cells in a fistula in ano: report of a case.We report a case of implantation of tumor cells within a fistula in ano. A 36-year-old man with a 16-year history of an anal fistula underwent an operation for rectal carcinoma. Three weeks later, the anal fistula was resected. A histological examination of the specimen showed atypical cells; moreover, rectal carcinoma had proliferated in the granulation tissue lying underneath the intact squamous epithelium. Because there was no continuity to the rectal carcinoma or the anal glands, we diagnosed implantation of rectal cancer cells in a fistula in ano.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
3/12. Synchronous squamous and glandular neoplasia of the anal canal.A 48 year old man presented with invasive adenocarcinoma in the wall of a non-healing anal fistula. The subsequent abdomino-perineal resection specimen showed residual invasive carcinoma coexisting with in situ carcinoma of anal glands as well as in situ squamous carcinoma of the anal canal. The epithelium of the anal canal had koilocytotic features. dna hybridisation studies by the dot blot technique showed weak positivity for human papillomavirus (HPV) subtypes 16, 18. This case illustrates a number of important points--namely, anal fistulas, particularly non-healing fistulas should be biopsied to exclude malignancy; some adenocarcinomas of the anal arise in anal glands; the coexistence of glandular and squamous carcinoma with evidence of HPV infection is highly reminiscent of similar synchronous lesions of the uterine cervix and suggests that HPV may have an aetiological role in both squamous and glandular carcinomas of the anal canal.- - - - - - - - - - ranking = 8keywords = gland (Clic here for more details about this article) |
4/12. Mucinous adenocarcinoma associated with fistula in ano: report of a case.We present a case of the rare occurrence of a mucus-secreting adenocarcinoma originating in an anal gland. A 37-year-old diabetic man had an anal fistulotomy 16 years before. He had four ischiorectal abscesses in a 6-month period. A seton was inserted in a complex fistula tract in the left anterior lateral aspect. Due to delayed healing, a new surgical exploration was carried out; pathological analysis of the curetted mucinous tissue revealed a mucoid adenocarcinoma. Surgical resection is the first choice of curative treatment, and additional treatments include chemotherapy, radiotherapy and brachytherapy.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
5/12. The role of fistulography in fistula-in-ano. Report of five cases.A retrospective review of 27 patients undergoing anal fistulography is presented. The etiology of the 27 fistulas studied are as follows: cryptoglandular infection in 18, IBD in 7 (Crohn's 6, CUC 1), iatrogenic in 1, and foreign body perforation in 1. Twenty-six fistulograms revealed either direct communication with the anus or rectum, or abscess cavities/tracts, or both. Two fistulograms revealed no radiographic evidence of fistula (one patient had two fistulograms). In 13 of the 27 patients (48 percent) information obtained from the fistulograms revealed either unexpected pathology (n = 7) or directly altered surgical management (n = 6). We conclude that anal fistulography in properly selected patients may add useful information for the definitive management of fistula-in-ano.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
6/12. Perianal mucinous adenocarcinoma.Perianal mucinous adenocarcinoma, also known as anal duct or anal gland carcinoma, is a rare tumor usually associated with chronic fistulae-in-ano. Whether the tumor occurs primarily and the fistula is a secondary manifestation, or whether this tumor arises in a chronic fistulous tract is debatable. diagnosis can be made only by open deep biopsy of the buttock mass, and, due to the low grade histologic appearance of the malignancy, an incorrect diagnosis is frequently made. Treatment is abdominoperineal resection with wide removal of the buttock mass.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
7/12. Perianal mucinous adenocarcinoma: a clue to its pathogenesis.The case of a 49 year old male patient who presented with perianal mucinous adenocarcinoma is presented. This is a rare anal tumour with a low grade, well-differentiated histological pattern. Its pathogenesis remains obscure, although a long antecedent history of fistula in ano and associated perianal sepsis is characteristic. The exact etiological relationship with anal fistula is not clearly established. The upper rectum is usually spared. Perianal Paget's disease is often seen in association with the tumour. Metastases occur late and spread is usually to the inguinal group of lymph nodes. Clinical diagnosis is often delayed and difficult. Treatment is abdominoperineal resection with block dissection of the inguinal lymph nodes if the glands are involved.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
8/12. Mucinous adenocarcinoma developing in chronic anal fistula: report of two cases and review of the literature.Mucinous adenocarcinoma developing in a chronic anal fistula is a rare tumor of the anus of which there are less than 150 reported cases. There has been some debate as to whether the fistula is the source of the tumor, or whether the fistula is the presenting feature of a slow-growing, indolent carcinoma. Two recent cases seen at our hospital are presented, along with a review of the literature and what we feel to be strong evidence that the fistula and associated anal glands are indeed the source of this unusual tumor.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
9/12. Primary adenocarcinoma of an anal gland with secondary perianal fistulas.A case of primary mucinous (colloid) adenocarcinoma associated with multiple perianal fistulas and a supra-anal intergluteal abscess of a short duration is described. The origin of this tumor has been much debated. Some believe that the tumor occurs primarily in an anal duct or its glands with secondary fistula formation, whereas others claim that the tumor arises in a chronic fistulous tract. The present study substantiates the former concept on the basis of the mode of clinical presentation and the pathologic findings of a large tumor, without involvement of the anorectal mucosa. The residual anal ducts and glands were found in close relationship with the tumor.- - - - - - - - - - ranking = 6keywords = gland (Clic here for more details about this article) |
10/12. Mucinous adenocarcinoma in anorectal fistulae.Mucinous adenocarcinoma arising in an anorectal fistula is an uncommon condition which gives rise to difficult problems of diagnosis and pathogenesis. The clinical history and pathology of seven patients are described and compared with six patients in whom anal fistulae were lined by normal rectal mucosa or 'misplaced glands'. In five of the cases granulomas were present which were a further cause of diagnostic difficulty. The evidence from this study suggests that the fistulous tracks are congenital duplications of the lower end of the hind gut lined by rectal mucosa which is prone to malignant change to mucinous adenocarcinoma. The prognosis after excision of the rectum is good.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
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