Cases reported "Q Fever"

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1/7. q fever--california, georgia, pennsylvania, and tennessee, 2000-2001.

    q fever is a zoonotic disease caused by the bacterium coxiella burnetii. The most common reservoirs are domesticated ruminants, primarily cattle, sheep, and goats. humans acquire q fever typically by inhaling aerosols or contaminated dusts derived from infected animals or animal products. Its highly infectious nature and aerosol route of transmission make C. burnetii a possible agent of bioterrorism. Although up to 60% of initial infections are asymptomatic, acute disease can manifest as a relatively mild, self-limited febrile illness, or more moderately severe disease characterized by hepatitis or pneumonia. It manifests less commonly as myocarditis, pericarditis, and meningoencephalitis. Chronic q fever occurs in <1% of infected patients, months or years after initial infection. chronic disease manifests most commonly as a culture-negative endocarditis in patients with valvular heart disease. During 2000-2001, a total of 48 patients who met the case definition of q fever were reported to CDC. This report describes the case investigations for six of these patients, which indicate that these persons acquired q fever probably through direct or indirect contact with livestock. To enhance surveillance efforts, health-care providers should report cases of q fever to state health departments.
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2/7. An outbreak of cat-associated q fever in the united states.

    q fever is usually acquired by contact with aerosols generated during parturition of domestic ungulates (e.g., sheep, cows, goats). In the maritime provinces of canada, parturient cats have also been implicated in its transmission. A 66-year-old woman from eastern maine developed high fever, rigors, headache, myalgias, pulmonary infiltrates, and elevated hepatocellular enzymes, and the diagnosis of acute q fever was confirmed serologically. She and 14 other family members had attended a family reunion in maine 2 weeks earlier, when they were exposed to a parturient cat. All 11 adults and older children attending the reunion developed symptoms consistent with acute q fever. serum samples were obtained from 10 who attended the reunion and 8 who did not attend. Titers greater than or equal to 1:64 to coxiella burnetii were present in all who attended the reunion but in none of those who did not. Cat-associated q fever should be considered when sporadic cases of the disease occur in the united states.
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3/7. Truckin' pneumonia--an outbreak of q fever in a truck repair plant probably due to aerosols from clothing contaminated by contact with newborn kittens.

    We describe an outbreak of q fever affecting 16 of 32 employees at a truck repair plant. None of the cases were exposed to cattle, sheep or goats, the traditional reservoirs of q fever. The cases did not work, live on, or visit farms or attend livestock auctions. One of the employees had a cat which gave birth to kittens 2 weeks prior to the first case of q fever in the plant. The cat owner fed the kittens every day before coming to work as the cat would not let the kittens suckle. serum from the cat had high antibody titres to phase I and phase II coxiella burnetii antigens. The attack rate among the employees where the cat owner worked, 13 of 19 (68%), was higher than that of employees elsewhere, 3 of 13 (28%) [P less than 0.01]. The cat owner's wife and son also developed q fever. None of the family members of the other employees with q fever was so affected. We conclude that this outbreak of q fever probably resulted from exposure to the contaminated clothing of the cat owner.
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4/7. q fever. A call to heighten our index of suspicion.

    The prevalence of q fever infection is probably underestimated. In michigan, the first two reported human cases of q fever occurred in 1984. The case-patients lived in adjacent, rural counties and had multiple exposures to goats. We conducted a serosurvey of goat owners and a reference population to compare the prevalence of q fever antibodies in the two-county area. Goat owners were almost three times more likely to be seropositive with q fever antibodies than the reference population (43% vs 15%). Among goat owners, individual and household seropositivity prevalences were positively correlated with the number of goats, the number of positive goats, and the number of goat births on the farm. q fever should be considered more often in the differential diagnosis of patients with compatible illness, especially those with frequent animal contact.
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5/7. A fatal case of q fever hepatitis in a child.

    A two-year-old boy of Arabic extraction presented with progressive jaundice and prolonged pyrexia. Both IgM and IgG immunofluorescent antibody titers for q fever were 1:1280. Two goats and one cow of the domestic animals owned by the family also had positive antibody titers against q fever. In spite of antibiotic treatment with tetracyclines and chloramphenicol, the hepatic involvement progressed gradually. On the twentieth day of admission the child succumbed from hepatic failure. This child presents a rare case of fatal hepatic failure due to q fever.
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6/7. q fever epidemic in Victorian general practice.

    In 1979, 110 people associated with a local rural abattoir presented with an acute febrile illness thought to be q fever. Of these, 70 were shown by serotesting to have had q fever, and one was shown to have had leptospirosis alone. Four individuals had mixed infections of q fever with another zoonotic infection, two with leptospirosis, and two with brucellosis. Only 44% of suspected cases of q fever were shown to have complement-fixing antibodies to q fever four weeks after the infection, but 74% had anti-bodies 12 weeks after infection. This epidemic of q fever occurred soon after the abattoir began to slaughter feral goats for the first time; there is reason to believe that the epidemic may have been related to the introduction of this practice.
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7/7. coxiella burnetii (q fever) pneumonia.

    pneumonia is one manifestation of acute q fever following infection with coxiella burnetii. Fever, headache, and myalgia dominate the clinical picture of q fever pneumonia. cough is nonproductive and may be absent despite the presence of pneumonia. While in most instances pneumonia results in an illness of mild-to-moderate severity, on occasion it is rapidly progressive and results in respiratory failure. infection occurs as a result of inhalation of contaminated aerosols. Infected cattle, sheep, and goats are the usual reservoirs for this zoonosis. In some areas, infected parturient cats serve as the reservoir, and in such instances, rounded opacities are seen on the chest radiograph. The diagnosis of C. burnetii pneumonia is usually confirmed by demonstration of a fourfold or greater rise in antibody titer. Treatment is usually with a tetracycline or rifampin for 7 to 10 days.
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