Cases reported "Pulmonary Heart Disease"

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1/8. Microscopic pulmonary tumour embolism: an unusual presentation of thymic carcinoma.

    The present report describes the first reported case of microscopic pulmonary tumour embolism (MPTE) from thymic carcinoma. The carcinoma was discovered during an autopsy in a 55-year-old man who had undergone surgery for a pilonidal sinus two weeks before presentation. Pulmonary thromboembolism was suspected. This case was unusual because MPTE has never before been associated with thymic carcinoma, MPTE was the first clinical indication of an occult malignancy, and the clinical presentation was that of sudden onset of dyspnea associated with acute cor pulmonale. The cause of death was determined to be hypoxia secondary to extrinsic compression of the right pulmonary artery and extensive tumour emboli in the small arteries, arterioles and venules of the pulmonary parenchyma. A review of the clinical presentation and diagnosis of MPTE is included.
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keywords = thromboembolism
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2/8. Pulmonary tumor embolism: a review of the literature.

    dyspnea in a patient with cancer may have several causes, including infection, thromboembolism, metastases, and therapeutically induced cardiopulmonary disease. Pulmonary tumor embolism is an uncommon cause. Occlusion of the pulmonary microvasculature by tumor cells and associated thrombi can produce a subacute and progressive clinical picture that resembles thromboembolic disease. Unfortunately, microscopic tumor embolism is recognized rarely before death because of difficulty in establishing the diagnosis. We provide a review of the literature about the evaluation and diagnosis of this rare clinical entity.
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ranking = 1
keywords = thromboembolism
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3/8. Successful pulmonary thromboendarterectomy for chronic thromboembolic pulmonary hypertension associated with anticardiolipin antibodies: report of a case.

    Chronic pulmonary thromboembolism with pulmonary hypertension is a rare but most unique syndrome in the broad spectrum of pulmonary embolism. This report describes a successful pulmonary thromboendarterectomy performed for a totally occluded right pulmonary artery on a 43 year old man who presented with positive cardiolipin antibodies. The surgery was performed through a median sternotomy with cardiopulmonary bypass and intermittent periods of deep hypothermic circulatory arrest. We are convinced that this method allows for complete removal of the thrombotic obstruction and should be the procedure of choice for patients with very proximal obstruction of a pulmonary artery.
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ranking = 1
keywords = thromboembolism
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4/8. Cor pulmonale as a complication of methylmalonic acidemia and homocystinuria (Cbl-C type).

    We report an infant with a bronchiolitis-like illness and rapid deterioration who developed a cor pulmonale-like picture with a dilated right ventricle. Urinary organic acid assays established a probable diagnosis of Cbl-C-type methylmalonic aciduria, later confirmed by complementation studies. Despite medical intervention and cyanocobalamin treatment the patient died on his tenth hospital day. Postmortem examination showed the presence of thromboemboli in the pulmonary circulation. We hypothesize that acute cor pulmonale developed in this infant secondary to thromboembolism of his pulmonary circulation. A review of the literature shows that thromboembolism may be a part of this disease process.
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ranking = 2
keywords = thromboembolism
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5/8. Cor pulmonale: a lethal complication of ventriculoatrial CSF diversion.

    We report the case of a child with cor pulmonale due to chronic thromboembolism from a ventriculoatrial shunt. The patient's pulmonary hypertension and heart failure did not resolve after removal of the atrial catheter and conversion to a ventriculoperitoneal system, and death ensued 2 months later. The reasons for the historical ascendancy of ventriculoperitoneal over ventriculoatrial shunts must be recalled when circumstances make the peritoneal cavity an unsuitable receptacle for CSF diversion. patients with ventriculoatrial shunts must be monitored for cardiopulmonary complications.
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ranking = 1
keywords = thromboembolism
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6/8. Idiopathic pulmonary arterial trunk aneurysm presenting as cor pulmonale: report of a case.

    An elderly woman who presented with cor pulmonale and intractable right heart failure was found at autopsy to have a thrombosed aneurysm of the pulmonary arterial trunk. This case is unusual in that no associated congenital cardiopulmonary anomaly, vascular myxoid degeneration, pulmonary parenchymal disease, or thromboembolism was found.
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ranking = 1
keywords = thromboembolism
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7/8. Acute massive (pericardial effusive) pulmonary thromboembolism--pulmonary embolectomy revisited.

    The most recent patient in a 13-year experience with 14 patients suffering massive pulmonary thromboembolism requiring pulmonary thromboembolectomy is the focus of this report. This 40-year-old woman not only survived life-threatening acute hypoxemia and right heart failure, but was also found to have developed a unique transudative 700 cc pericardial effusion. pulmonary artery pressure was 90/30 (mean 50 mmHg), accompanied by 17 mm right ventricular alternans. Systemic alternans and tamponade physiology were absent. This unusual natural model for acute right heart failure illustrates a novel mechanism for pericardial effusion physiology.
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ranking = 5
keywords = thromboembolism
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8/8. Case report. Acute cor pulmonale due to massive pulmonary embolism and successful response to thrombolytic therapy.

    The proper place of thrombolytic agents in the management of pulmonary embolism is not yet well defined. A number of survivors of acute massive pulmonary thromboembolism remain in a delicate balance of hemodynamic compensation and where recurrent emboli could frequently be fatal. Successful response to urokinase therapy in such a case is presented and the status of currently available thrombolytic drugs is discussed. We suggest that thrombolytic therapy in massive pulmonary embolism would provide greater hemodynamic reserve, alleviate shock, minimize the chances of recurrent emboli and prevent permanent impairment to the pulmonary vascular bed.
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ranking = 1
keywords = thromboembolism
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