1/9. Acute fatty liver of pregnancy showing microbial infection in the liver.A 24-year-old, nulliparous woman in her 30th week of pregnancy was admitted due to threatened premature delivery. Ritodrin chloride relieved the premature contraction of the uterus but jaundice and drowsiness appeared 7 weeks later. Laboratory data revealed disseminated intravascular coagulation (DIC) with intrahepatic cholestasis, and ultrasound examination showed fatty liver. The patient was diagnosed with acute fatty liver of pregnancy (AFLP). Emergency delivery by Caesarean section was performed at 37 weeks of pregnancy and the liver function and DIC improved immediately. Liver biopsy 13 days after delivery showed nuclear swelling and cytoplasmic ballooning with mild fatty deposition. These findings were relatively compatible with acute AFLP. Higher magnification and electron microscopy revealed intracytoplasmic bacteria and fungus in the residual stage. The bacterial infection could be considered related to AFLP.- - - - - - - - - - ranking = 1keywords = bacterial infection (Clic here for more details about this article) |
2/9. Prenatal transmission of dengue: two new cases.dengue is commonly observed in most tropical countries, but its transmission from mother to fetus has not been frequently described. We report two such cases. The first signs of dengue in the infants appeared on the 3rd and 9th days of life. In both, a bacterial infection was suspected initially. In areas where it is endemic, the diagnosis of dengue should be considered in the neonate with signs of bacterial infection. When dengue is suspected in a pregnant woman, laboratory investigation and extended observation of the newborn are advised.- - - - - - - - - - ranking = 2keywords = bacterial infection (Clic here for more details about this article) |
3/9. Leiden mutation, bed rest and infection: simultaneous triggers for maternal deep-vein thrombosis and neonatal intracranial hemorrhage?The possible etiologic roles of infection and bed rest are discussed in connection with a case of maternal homozygous Leiden mutation leading to prematurity, maternal deep-vein thrombosis and neonatal intracranial hemorrhage in a heterozygous premature baby. Maternal bacterial infection and bed rest may trigger deep-vein femoral thrombosis in women with a homozygous Leiden mutation on tocolytic therapy for the treatment of premature labor. The neonate carrying at least one mutated allele of factor v Leiden might be at risk for the development of intracranial hemorrhage.- - - - - - - - - - ranking = 1keywords = bacterial infection (Clic here for more details about this article) |
4/9. achromobacter xylosoxidans. An unusual neonatal pathogen.Perinatal acquisition of a rare pediatric pathogen, achromobacter xylosoxidans, with evidence for in utero transmission, is described. Cultures from the mother and neonate demonstrated A. xylosoxidans. An ascending bacterial infection in the mother with clinical chorioamnionitis is presented as the probable mode of transmission. Postmortem examination of the infant confirmed achromobacter meningitis. In contrast to the current case with transmission from mother to neonate, previously published neonatal cases of achromobacter infections indicate that nosocomial transmission of the organism is most common (79%). In addition, the literature review revealed a high mortality associated with meningitis (77%), frequent hydrocephalus, and subsequent neurologic sequelae (36%). To the authors' knowledge, this is the first documented case of maternal-fetal transfer of A. xylosoxidans.- - - - - - - - - - ranking = 1keywords = bacterial infection (Clic here for more details about this article) |
5/9. Promyelocytic leukaemoid reaction: an atypical presentation of mycobacterial infection.A young woman presented with mild pyrexia and antepartal haemorrhage due to disseminated intravascular coagulation. She had pancytopenia in the peripheral blood and granulocytic maturation arrest at the promyelocyte stage in the bone marrow. Her urine and bone marrow grew mycobacterium kansasii on culture. Antituberculous treatment eliminated the infection and restored the normality of bone marrow and peripheral blood.- - - - - - - - - - ranking = 4keywords = bacterial infection (Clic here for more details about this article) |
6/9. Specific health problems of Southeast Asian refugees in middle tennessee.Three diseases representative of specific health conditions affecting the Southeast Asian refugees living in middle tennessee are leprosy (chronic bacterial infections), liver fluke infection (parasitic diseases), and hemoglobin e-beta-thalassemia (hematologic disorders). In this paper we discuss incidence, causative agent, mode of transmission, metabolic abnormalities, and management of these conditions.- - - - - - - - - - ranking = 1keywords = bacterial infection (Clic here for more details about this article) |
7/9. Necrotizing funisitis and herpes simplex infection of placental and decidual tissues: study of four cases.Necrotizing funisitis (NF) is a macroscopically and microscopically distinctive pattern of umbilical cord inflammation recently heralded as presumptive of congenital syphilis. Four nonsyphilitic cases are presented in which herpes simplex virus (HSV) 2 antigen was demonstrated in the placenta by immunohistochemistry. The clinicopathologic findings in one case, including HSV 2 antigen in amniotic epithelium, subamniotic chorion, and wharton jelly, indicate that NF was caused by chronic ascending primary HSV 2 infection, whereas those of the other three cases with HSV 2 Ag confined to decidual cell clusters suggest that NF was caused by chronic ascending bacterial infection and that latent endometrial HSV 2 infection was fortuitous. We conclude that (1) NF is caused by protracted inflammation of a structure whose normal anatomy precludes removal of inflammatory debris; (2) no single pathogen causes NF; and (3) NF is strongly associated with latent endometrial HSV 2 infection, which should be sought in all instances. Although latent HSV 2 endometrial infection may be more prevalent than currently recognized, we speculate that its strong association with NF may be more than causal; whereas the usual ascending bacterial infection leads to labor before NF has had sufficient time to develop, latent endometrial HSV 2 infection may alter local paracrine factors and delay parturition for the time sufficient to permit NF, a morphological hallmark of chronicity, to become apparent.- - - - - - - - - - ranking = 2keywords = bacterial infection (Clic here for more details about this article) |
8/9. Intravenous immunoglobulin replacement therapy for common variable immunodeficiency during pregnancy.patients with common variable immunodeficiency (CVID), characterized by impaired antibody production, have a high susceptibility to bacterial infections and need supplements of immunoglobulin g (IgG). We report two pregnancies in a woman with CVID. Differences in the outcome of the two pregnancies suggest the need for adjustment of replacement therapy during pregnancy.- - - - - - - - - - ranking = 1keywords = bacterial infection (Clic here for more details about this article) |
9/9. A new type of fulminant group A streptococcal infection in obstetric patients: report of two cases.A new type of fulminant group A streptococcal infection in obstetric patients is described. The illness occurs in late stage of pregnancy, and is preceded by an episode of upper respiratory tract infection. This is followed by sudden onset of septicemia, subsequent hematogenous infection of the myometrium by the bacteria, and development of acute purulent myometritis. shock and multiorgan failure ensue rapidly. prognosis of both the mother and fetus is very poor, as recognition of this serious condition is difficult until the late stage of the disease. This type of infection is entirely different from classical puerperal sepsis in that the illness starts before delivery, and that there was no evidence of ascending bacterial infections of the birth canal, such as acute endometritis or chorioamnionitis, in affected mothers. The underlying mechanism for this serious infection remains unknown.- - - - - - - - - - ranking = 1keywords = bacterial infection (Clic here for more details about this article) |