Cases reported "Pigmentation Disorders"

Filter by keywords:



Filtering documents. Please wait...

1/18. Pigmented purpuric dermatosis in a young male.

    The pigmented purpuric dermatoses (PPD) are a group of disorders that most often occur on the lower extremities of middle-aged adults as asymptomatic, yellow-orange patches with petechiae. The PPD represent a benign, often chronic, capillaritis of unknown cause. We present a case of PPD on the abdomen of a young male and emphasize careful observation in such a patient to reveal possible progression to purpuric mycosis fungoides.
- - - - - - - - - -
ranking = 1
keywords = mycosis fungoides, fungoides, mycosis
(Clic here for more details about this article)

2/18. Monoclonal rearrangement of the T cell receptor gamma-chain in lichenoid pigmented purpuric dermatitis of gougerot-blum responding to topical corticosteroid therapy.

    Lichenoid pigmented purpuric dermatitis of Gougerot-Blum belongs to a group of closely related disorders which are termed pigmented purpuric dermatoses. It clinically manifests itself with grouped lichenoid papules in association with purpuric lesions. We report a case of lichenoid pigmented purpuric dermatitis of Gougerot-Blum with a heavy band-like CD4-positive lymphocytic infiltrate and clonal rearrangements of the gamma-chain of the T cell receptors as detected by polymerase chain reaction/denaturing gradient gel electrophoresis. Monoclonal expansion of T cells in combination with certain histological features of mycosis fungoides (MF) might support a biological relationship between lichenoid pigmented purpuric dermatitis of Gougerot-Blum and MF. However, prompt clinical response to topical steroid therapy supports the benign clinical nature of our case.
- - - - - - - - - -
ranking = 1
keywords = mycosis fungoides, fungoides, mycosis
(Clic here for more details about this article)

3/18. mycosis fungoides.

    The case of a 46-year-old woman with poikiloderma vasculare atrophicans is discussed. It is a rare clinical form of patch-stage mycosis fungoides characterized by generalized poikiloderma, atrophy, mottled dyspigmentation, and telangiectases.
- - - - - - - - - -
ranking = 1.8019957682666
keywords = mycosis fungoides, fungoides, mycosis
(Clic here for more details about this article)

4/18. Minimal residual disease in hypopigmented mycosis fungoides.

    We describe the case of a 13-year-old boy with stage I hypopigmented mycosis fungoides in whom minimal residual disease was detected with T-cell receptor gamma-polymerase chain reaction after the disease was in complete clinical remission. We further cloned and sequenced the T-cell receptor gamma-polymerase chain reaction product of the lesion in remission and found that the original T-cell clone still existed in decreased amounts. The patient was followed up for 3 1/2 years without any new lesions developing. The clinical significance of this residual malignant T-cell clone in mycosis fungoides remains to be elucidated.
- - - - - - - - - -
ranking = 6
keywords = mycosis fungoides, fungoides, mycosis
(Clic here for more details about this article)

5/18. mycosis fungoides presenting as pigmented purpuric dermatitis.

    mycosis fungoides, a cutaneous T-cell lymphoma, typically presents as indolent, progressive, and persistent erythematous patches or plaques with mild scaling and over time can evolve into tumor stage with tumor nodules. Other presentations include eczematous, psoriasiform, poikilodermatous, and hypopigmented patches. We report mycosis fungoides in a 14-year-old boy presenting as pigmented purpuric dermatitis and review the relevant literature. This is a rare presentation of a condition that is uncommon in the pediatric population. In our patient, histologic features were typical of mycosis fungoides presenting as pigmented purpuric dermatitis. The clinical features, pathology, molecular biology, and the relationship between these two entities are discussed.
- - - - - - - - - -
ranking = 1.4034925944666
keywords = fungoides
(Clic here for more details about this article)

6/18. Cutaneous phaeohyphomycosis caused by a rare fungal pathogen, Hormonema dematioides: successful treatment with ketoconazole.

    Annular, fungating, ulcerated lesions developed on both hands of a 64-year-old immunocompetent man 2 months after he was cut with barbed wire. A dematiaceous mold, Hormonema dematioides, heretofore not definitively associated with human disease, was grown from two separate tissue specimens during a period of 9 days. Histopathologic examination demonstrated rare small, periodic acid-Schiff-positive, hyaline, yeastlike organisms in tissue. Twelve weeks of empiric therapy with ketoconazole, 400 mg/day, was curative.
- - - - - - - - - -
ranking = 0.28334649143554
keywords = mycosis
(Clic here for more details about this article)

7/18. Progression of pigmented purpura-like eruptions to mycosis fungoides: report of three cases.

    The cases of three relatively young male patients with pigmented purpura-like eruptions evolving to mycosis fungoides are described. Initially, the eruptions, both clinically and histologically, very closely resembled pigmented purpuric dermatitis. After a follow-up period averaging 8.4 years, diagnostic histologic changes of mycosis fungoides were observed. Although uncommon, mycosis fungoides should be considered in the differential diagnosis of pigmented purpuric eruptions.
- - - - - - - - - -
ranking = 7
keywords = mycosis fungoides, fungoides, mycosis
(Clic here for more details about this article)

8/18. Premycotic poikiloderma, mycosis fungoides and cutaneous squamous cell carcinoma. Two cases and a discussion of their relevance.

    Two patients with premycotic poikiloderma developed one squamous cell carcinoma each. A review of the literature reveals 28 reported cases of this association, but in 26 of these the patient had been exposed to carcinogens. Our patients had no history of exposure to carcinogenic agents. In both our cases, the squamous carcinomas behaved aggressively. The possible relationship with the poikiloderma is discussed.
- - - - - - - - - -
ranking = 4
keywords = mycosis fungoides, fungoides, mycosis
(Clic here for more details about this article)

9/18. Hypopigmented mycosis fungoides. Speculations about the mechanism of hypopigmentation.

    Hypopigmented, nonatrophic macules are an unusual manifestation of lesions of early mycosis fungoides. Presented herein is a patient with such lesions and an unusual mask-like hypopigmentation of the face. We review both the clinical and microscopic findings in this patient and in previously reported patients with hypopigmented lesions of mycosis fungoides. Finally, speculation is made as to the mechanisms of the hypopigmentation.
- - - - - - - - - -
ranking = 6
keywords = mycosis fungoides, fungoides, mycosis
(Clic here for more details about this article)

10/18. Diffuse, progressive hyperpigmentation: an unusual skin manifestation of mycosis fungoides.

    Pigmentary changes in mycosis fungoides usually occur in association with poikiloderma atrophicans vasculare or following therapy and regression of lesions. Several cases of hypopigmented mycosis fungoides have also been reported. We present the case report of a patient who developed pruritic, diffuse macular hyperpigmentation of the skin. biopsy specimens from hyperpigmented skin revealed histologic and ultrastructural features typical of mycosis fungoides. Giant melanin granules were found in the tumor cells, as well as in keratinocytes and langerhans cells. As far as we know, this is the first report of cutaneous hyperpigmentation as a single presenting sign of mycosis fungoides.
- - - - - - - - - -
ranking = 5.0853422597022
keywords = mycosis fungoides, fungoides, mycosis
(Clic here for more details about this article)
| Next ->


Leave a message about 'Pigmentation Disorders'


We do not evaluate or guarantee the accuracy of any content in this site. Click here for the full disclaimer.