21/44. spinal cord compression from a thoracic paraganglioma: case report.A 34-year-old man with a 4-month history of midthoracic back pain sought treatment for a recent onset of lower extremity paresthesia and stiffness. A myelogram and computed tomographic myelogram disclosed an extradural block at the level of the 8th thoracic vertebral body with involvement of the pedicles, lamina, and spinous process. A posterior decompression of the spinal cord with subtotal resection of a highly vascular tumor was performed. The tumor was identified as a paraganglioma. In a second stage, the remainder of the tumor was embolized preoperatively, and gross total excision and sequential stabilization of the spine with a Luque rectangle and sublaminar wires were performed. The patient has been symptom free and without signs of a recurrence in the spine for over 13 months. A large abdominal paraganglioma was recently resected from its probable origin from the adventitia of the abdominal aorta.- - - - - - - - - - ranking = 1keywords = spinal (Clic here for more details about this article) |
22/44. Cervical paraganglioma with subsequent intracranial and intraspinal metastases. Case report.Paragangliomas, tumors derived from the extra-adrenal paraganglion system, have commonly been found in the retroperitoneum, abdomen, mediastinum, skull base, and neck. Rare intraspinal cases have included involvement of the cauda equina and filum terminale, and a recent case has been reported of thoracic cord paraganglioma with metastasis to the cauda equina. The authors present the case of a patient with a cervical paraganglioma who underwent subtotal resection followed by postoperative irradiation; she subsequently developed multiple intracranial and intraspinal metastases 7 months following the first decompression procedure.- - - - - - - - - - ranking = 6keywords = spinal (Clic here for more details about this article) |
23/44. Multiple spinal metastases from paraganglioma.Isolated vertebral body metastases from paraganglioma are exceedingly rare. They have been reported to occur in the presence of active primary tumor in the neck, local recurrence, or widespread metastases. A unique case of carotid body tumor (paraganglioma) is reported with the following features: (1) multiple vertebral body metastases (C6, T9, and L3) presenting with spinal cord compression, and no evidence of local recurrence or other metastatic disease; (2) absence of mitoses on the original specimen or the metastatic deposit; and (3) a prolonged interval (9 years) to the development of symptomatic metastases.- - - - - - - - - - ranking = 5keywords = spinal (Clic here for more details about this article) |
24/44. The evaluation of thoracic paraspinal neurogenic tumours. The role of magnetic resonance imaging.Paraspinal neurogenic tumours may have associated intraspinal tumour extension. It is important that such extension be accurately defined preoperatively in order that an appropriate surgical approach may be planned. It has been suggested in the literature that MRI (where available) should replace myelography and post myelographic CT in the preoperative evaluation of these patients. The literature is reviewed and the potential role of MRI is illustrated in three cases.- - - - - - - - - - ranking = 6keywords = spinal (Clic here for more details about this article) |
25/44. Aggressive papillary middle-ear tumor. A clinicopathologic entity distinct from middle-ear adenoma.A 29-year-old woman had a middle-ear mass that resulted in hearing loss and seventh-nerve palsy. The tumor invaded the petrous bone, the mastoid, at least one semicircular canal, and then extended into the posterior fossa. Microscopically, it consisted of complex, interdigitating papillae lined by uniform, cuboidal to low columnar cells. The cells resembled the epithelium of the normal middle ear and middle-ear adenoma, but the papillary architecture distinguished this neoplasm from the latter, nonpapillary tumors. Papillary middle-ear tumors are locally invasive. We propose the term "aggressive papillary middle-ear tumor" (APMET). Nine other examples of APMET have been reported under various diagnostic terms. All have been locally destructive with frequent intracranial invasion. Although none of the tumors has metastasized, one patient died of uncontrolled local disease. For this reason, APMET must be distinguished from nonpapillary middle-ear tumors.- - - - - - - - - - ranking = 0.78183649704712keywords = canal (Clic here for more details about this article) |
26/44. paraganglioma of the cauda equina: a case report.This case report describes a paraganglioma of the cauda equina in a 63 year old woman. Very few examples of paraganglioma have been recorded in this site. Histologically these neoplasms may have considerable similarity with ependymoma, the most common neoplasm of the lower spinal cord, and the diagnosis can be easily missed unless special techniques are employed. The clinical and pathological data obtained from this and the other reported examples suggests that paragangliomas of the cauda equina are benign, slowly growing neoplasms. In contrast to ependymomas and to paragangliomas elsewhere, they are well circumscribed, amenable to complete resection and have an excellent prognosis.- - - - - - - - - - ranking = 1keywords = spinal (Clic here for more details about this article) |
27/44. A case of spinal paraganglioma.The neuroradiologic finding of a paraganglioma in the vertebral canal is described here for the first time. These tumors occur more frequently than was previously presumed. Similarities with paragangliomas in the craniocervical region are apparent on angiograms. We consider angiography to be indicated when, in association with a spinal tumor, urinary biogenic amine levels are elevated. When necessary, embolization can be performed after angiography.- - - - - - - - - - ranking = 5.7818364970471keywords = spinal, canal (Clic here for more details about this article) |
28/44. Virilization due to a metastasizing granulosa cell tumor.This report describes a virilizing granulosa cell tumor in a postmenopausal woman. The tumor metastasized to the liver, urinary bladder, and spinal column. Although the bladder metastases were diagnosed initially as paraganglioma, review of the slides and the demonstration of abundant lipid within the tumor cells led to the correct diagnosis. The plasma testosterone and 17-hydroxyprogesterone levels were elevated, while the plasma 17-hydroxypregnenolone and dehydroepiandrosterone levels were normal, suggesting that the delta 4-pathway of testosterone biosynthesis was predominant in this tumor. Gonadotropin levels were suppressed and did not respond to gonadotropin-releasing hormone. Presumably, this suppression was due to an increase in the plasma testosterone level.- - - - - - - - - - ranking = 1keywords = spinal (Clic here for more details about this article) |
29/44. paraganglioma of the cauda equina. Report of a rare tumor.The rare occurrence of a paraganglioma of the cauda equina is described. The correct diagnosis was made only retrospectively after examination of a recurrence nine years after initial surgery. Paragangliomas have not been mentioned in large tabulations of spinal cord tumors, perhaps reflecting the fact that it is only within the last decade that such tumors have been recognized in this unusual location. A literature review has revealed six cases of paraganglioma of the cauda equina reported since 1970. An awareness of the possibility of a paraganglioma intimately associated with the spinal cord as well as the histopathologic appearance are the bases of a correct diagnosis. These tumors are histopathologically similar to paragangliomas in conventional locations, exhibit ultrastructural granules and may, as in the current case, also demonstrate argyrophilic granules.- - - - - - - - - - ranking = 2keywords = spinal (Clic here for more details about this article) |
30/44. Paragangliomas of the spinal canal.Paragangliomas are tumors arising in the paraganglia and rarely occur in the spinal canal. In the literature, 11 such cases have been reported. We present 7 additional cases, 3 of which were epidural in location in contrast to previously described intradural cases. The problems of histological diagnosis of these tumors are discussed. The value of determination of biogenic amines in the tumor tissue or the urine has been pointed out.- - - - - - - - - - ranking = 151.0054886249keywords = spinal canal, spinal, canal (Clic here for more details about this article) |
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