1/5. renin-producing serous cystoadenocarcinoma of the ovary: a case report.BACKGROUND: Only a few renin-producing ovarian tumors have been reported, and most such ovarian tumors have been sex cord/stromal tumors. renin-producing ovarian epithelial tumors are quite rare. CASE: A 46-year-old woman presented with hypertension and hypokalemia. Examinations of the patient revealed elevated plasma renin activity, hyperaldosteronism and a pelvic mass. Subsequently, a right ovarian tumor mass was resected. Microscopic observation of the tumor revealed a well-differentiated serous cystadenocarcinoma. Immediately after surgery, blood pressure, serum potassium, plasma renin activity and plasma aldosterone levels returned to normal ranges. RT-PCR analysis and immunohistochemical staining of this tumor indicated that it was producing renin. CONCLUSION: This is the first report of a renin-producing ovarian serous cystadenocarcinoma.- - - - - - - - - - ranking = 1keywords = aldosteronism (Clic here for more details about this article) |
2/5. Primary aldosteronism due to a malignant ovarian tumor.A case of a young woman with the syndrome of primary aldosteronism and malignant ovarian tumor is reported. Hormone studies revealed extremely high urinary aldosterone, undetectable plasma renin activity, elevated plasma 17beta estradiol and testosterone, and low plasma FSH and LH. plasma cortisol and urinary 17-hydroxycorticoids were at the upper normal limits. autopsy disclosed an ovarian tumor, histologically an arrhenoblastoma, with polymorphic aspects. The adrenal glands grossly were normal. aldosterone was found by the double radioisotopic technique in the neoplastic tissue.- - - - - - - - - - ranking = 5keywords = aldosteronism (Clic here for more details about this article) |
3/5. Autonomous aldosterone-secreting ovarian tumor.The case of a young woman with primary aldosteronism originating extraadrenally--ovarian tumor--is reported. Clinically she presented with uncontrolled hypertension. Biochemical and hormonal profiles showed features of aldosteronism. The primary was found in the left ovary. Following excision of the tumor, aldosteronism regressed completely. Microscopically, the tumor was of the lipid cell type. Nine months after surgery she is asymptomatic and well. review of the literature uncovered three previous reports of aldosterone-secreting ovarian tumors.- - - - - - - - - - ranking = 3keywords = aldosteronism (Clic here for more details about this article) |
4/5. Resistant hypertension associated with a renin-producing ovarian sertoli cell tumor.A 17-year-old girl with refractory, but nonmalignant, hypertension and hypokalemia is presented. A state of primary hyperreninism and secondary hyperaldosteronism was found to exist, together with a renin-producing Sertoli cell ovarian tumor. Upon removal of the tumor, this patient attained both a normotensive and a normokalemic state. A brief review is given of renal and nonrenal renin-producing tumors.- - - - - - - - - - ranking = 1keywords = aldosteronism (Clic here for more details about this article) |
5/5. Primary aldosteronism due to a malignant ovarian tumour.The case of a woman with autonomous aldosteronism, hypertension, and malignant ovarian tumour is reported. Hormone studies revealed high plasma aldosterone levels, and low plasma renin concentration. Following surgical removal of a malignant sex cord stromal tumour, the hyperaldosteronism regressed, and the hypertension improved. Subsequently the tumour recurred, as did hyperaldosteronism.- - - - - - - - - - ranking = 7keywords = aldosteronism (Clic here for more details about this article) |